Bioscience for Graduates from Other Scientific Disciplines

Department of Chemical Engineering, School of Chemical Engineering

College of Engineering and Physical Sciences


Code 18520

Level of study Second Year

Credit value 10

Semester 1

Module description

Cellular structure:
Structure and function of cellular components within eukaryotic and prokaryotic.

Cellular function and activity:
Description and control of catabolic and biosynthetic pathways: cellular thermodynamics (including derivation of cellular energy through oxidative and anaerobic generation of ATP) and polymerisation reactions;
Basic genetic mechanisms: DNA, RNA and protein synthesis in prokaryotic and eukyarotic cells;
Cellular signalling and control: endocrine, paracrine and synaptic signalling. Function of intracellular and cell-surface receptors (channel-linked, G-protein-linked and catalytic receptors);
Material transport: active and passive mechanisms;
Reproduction: meiosis and mitosis and the implications of terminal differentiation.

Cell culture:
Applications in biotechnology industry and medical research: brewing, cell culture (insect and animal), fermentation (bacteria and yeast), biocatalysis, bioremediation and food processing;
Methods for mammalian, insect and cell culture: Batch, fed-batch (perfusion for animal/insect cells) and continuous culture;
Scale-up of bioprocesses: fundamental scaling issues (mixing and power consumption). Experimental and mathematical predictive scale-down models of large scale;
Analytical cytology: methods for the measurement, monitoring and control of bioprocesses including: flow cytometry, image analysis, microscopy, NIR-spectroscopy and the more traditional microbiological analysis.

Cellular organisation:
Structure and function of primary tissue types: muscle, nervous, epithelial and connective tissues;
Anatomy and physiology of biological systems and structures important in "molecular delivery" eg digestive system, respiratory systems (including nasal physiology) and skin.

Teaching and learning methods

Lectures, tutorials and lab classes