Structure and function of cellular components within eukaryotic and prokaryotic.
Cellular function and activity:
Description and control of catabolic and biosynthetic pathways: cellular thermodynamics (including derivation of cellular energy through oxidative and anaerobic generation of ATP) and polymerisation reactions;
Basic genetic mechanisms: DNA, RNA and protein synthesis in prokaryotic and eukyarotic cells;
Cellular signalling and control: endocrine, paracrine and synaptic signalling. Function of intracellular and cell-surface receptors (channel-linked, G-protein-linked and catalytic receptors);
Material transport: active and passive mechanisms;
Reproduction: meiosis and mitosis and the implications of terminal differentiation.
Applications in biotechnology industry and medical research: brewing, cell culture (insect and animal), fermentation (bacteria and yeast), biocatalysis, bioremediation and food processing;
Methods for mammalian, insect and cell culture: Batch, fed-batch (perfusion for animal/insect cells) and continuous culture;
Scale-up of bioprocesses: fundamental scaling issues (mixing and power consumption). Experimental and mathematical predictive scale-down models of large scale;
Analytical cytology: methods for the measurement, monitoring and control of bioprocesses including: flow cytometry, image analysis, microscopy, NIR-spectroscopy and the more traditional microbiological analysis.
Structure and function of primary tissue types: muscle, nervous, epithelial and connective tissues;
Anatomy and physiology of biological systems and structures important in "molecular delivery" eg digestive system, respiratory systems (including nasal physiology) and skin.