Relevant Publications

Reviews on Environmental Metabolomics

J.G. Bundy, M.P. Davey, M.R. Viant, Environmental metabolomics: A critical review and future perspectives. Metabolomics 5, 3-21 (2009).

M.R. Viant, Recent developments in environmental metabolomics. Molecular Biosystems 4, 980-986 (2008).

M.R. Viant, Metabolomics of aquatic organisms: the new omics on the block. Mar. Ecol. Prog. Series 332, 301-306 (2007).

C.-Y. Lin, M.R. Viant and R.S. Tjeerdema, Metabolomics: Methodologies and Applications in the Environmental Sciences. J. Pestic. Sci. 31, 245-251 (2006).

Method papers - Sample preparation

H. Wu, A.D. Southam, A. Hines and M.R. Viant, High throughput tissue extraction protocol for NMR- and MS-based metabolomics. Anal. Biochem. 372, 204-212 (2008).

S. Tiziani, A.-H. Emwas, A. Lodi, C. Ludwig, C.M. Bunce, M.R. Viant and U.L. Günther, Optimised Metabolite Extraction from Blood Serum for 1H Nuclear Magnetic Resonance Spectroscopy. Anal. Biochem. 377, 16-23 (2008).

C.-Y. Lin, H. Wu, R.S. Tjeerdema and M.R. Viant, Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics. Metabolomics 3, 55-67 (2007).

Methods papers - NMR spectroscopy and mass spectrometry

R. J.M. Weber, A.D. Southam, U. Sommer, and M.R. Viant, Characterization of Isotopic Abundance Measurements in High Resolution FT-ICR and Orbitrap Mass Spectra for Improved Confidence of Metabolite Identification. Anal. Chem. 83 3737-3743 (2011).

M.R. Viant, D.W. Bearden, J.G. Bundy, I.W. Burton, T.W. Collette, D.R. Ekman, V. Ezernieks, T.K. Karakach, C.Y. Lin, S. Rochfort, J.S. de Ropp, Q. Teng, R.S. Tjeerdema, J.A. Walter, H. Wu, International NMR-based Environmental Metabolomics Intercomparison Exercise. Environ. Sci. Technol. 43, 219-225 (2009).

A.D. Southam, T.G. Payne, H.J. Cooper, T.N. Arvanitis, M.R. Viant, Spectral Stitching Method Increases the Dynamic Range and Mass Accuracy of Wide-scan Direct Infusion nano-Electrospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry-based Metabolomics. Anal. Chem. 79, 4595-4602 (2007).

M.R. Viant, Improved Methods for the Acquisition and Interpretation of NMR Metabolomic Data, Biochem. Biophys. Res. Comm. 310, 943-948 (2003).

Methods papers - Bioinformatics

R.J.M Weber, and M. R. Viant, MI-Pack: Increased confidence of metabolite identification in mass spectra by integrating accurate masses and metabolic pathways. Chemometr. Intell. Lab. Syst. 104, 75-82 (2010).

S. Tiziani, A. Lodi, C. Ludwig, H.M. Parsons and M.R. Viant, Effects of the application of different window functions and projection methods on processing of 1H J-resolved nuclear magnetic resonance spectra for metabolomics. Anal. Chim. Acta 610, 80-88 (2008).

H.M. Parsons, C. Ludwig, U.L. Günther and M.R. Viant, Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation. BMC Bioinformatics 8, 234 (2007).