Selected publications

Recent publications supported by work carried out at the Mitochondrial Profiling Centre:

Barlow, J. and Solomon, T. (2018). Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells. Metabolism.

Barlow, J., Carter, S., and Solomon, T. (2018). Skeletal muscle to pancreatic beta-cell crosstalk: Probing the effect of IL-6 on insulin secretion by INS-1 832/3 insulinoma cells under diabetic-like conditions. Int J of Mol Sci.

Barlow, J., Solomon, T., and Affourtit, C. (2018). Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity – novel mechanistic insight from real-time analysis of oxidative phosphorylation. PLOS one. DOI: 10.1371/journal.pone.0199505

Fletcher, RS. Ratajczak, J. Doig, CL. Oakey, LA. Callingham, R. Xavier, GDS. Garten, A. Elhassan, YS. Redpath, P. Migaud, ME. Philp, A. Brenner, C. Canto, C. Lavery, GG. (2017). Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Mol. Metab. DOI: 10.1016/j.molmet.2017.05.011

Jeromson, S. Mackenzie, I. Doherty, M. Whitfield, P. Bell, G. Dick, J. Shaw, A. Rao, F. Ashcroft, S. Philp, A. Galloway, S. Gallagher, I. Hamilton, DL (2017). Lipid remodelling and an altered membrane proteome may drive the effects of EPA and DHA treatment on skeletal muscle glucose uptake and protein accretion. Am J Physiol Endocrinol Metab. DOI: 10.1152/ajpendo.00438.2015

Doig, CL. Fletcher, RS. Morgan, SA. McCabe, EL. Tomlinson, JW. Stewart, PM. Philp, A. Lavery, GG. (2017). 11β-HSD1 determines the set-point of brown adipose tissue response to glucocorticoids. Endocrinology. DOI: 10.1210/en.2016-1722

Philp, AM. Collier, RL. Grover, LM. Davis, ET. Jones, SW. (2017). Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis. Sci Rep. DOI: 10.1038/s41598-017-04119-4

Philp, AM. Raja, S. Philp, A. Newton Ede, MP. Jones, SW. (2017). The Effect of Vancomycin and Gentamicin Antibiotics on Human Osteoblast Proliferation, Metabolic Function, and Bone Mineralization. Spine. DOI: 10.1097/BRS.0000000000001712

Newton Ede, MP. Philp, AM. Philp, A. Richardson, SM. Mohammad, S. Jones, SW. (2016). Povidone-Iodine Has a Profound Effect on In Vitro Osteoblast Proliferation and Metabolic Function and Inhibits Their Ability to Mineralize and Form Bone. Spine. DOI:10.1097/BRS.0000000000001332