Welcome to the BASIL-2 Trial Webpage Recent publication by Kevin Barraclough and Professor Andrew Bradbury (BASIL-2 CI) on "Chronic limb threatening ischaemia"; Read the article here. The 'BASIL Trials Investigator Meeting' at the VSGBI Annual Scientific Meeting (23rd November 2017); View the presentation here. Recently published subgroup analysis by Popplewell et al. of patients randomised into the original BASIL trial with infrapopliteal disease reafirming the need for RCTs such as BASIL-2 and BEST-CLI; Read the article here. Retrospective analysis by Darling et al. demonstrating "improved 6-month woundhealing, higher freedom from restenosis, improved patency rates, significantly fewer reinterventions, and higher survival [within 3 years]" for primary bypass over primary angioplasty /stent; Read the article here Article by Barry Katzen on "Endovascular therapy for critical limb ischaemia: When is enough, enough?"; Read the article here. In 'Basil 2' Trial OverviewBasil 2InvestigatorsParticipantsContact Introduction Basil 2 is a multi-centre randomised controlled trial to find out if a ‘vein bypass first’ or a ‘best endovascular first’ revascularisation strategy is best, in terms of either clinical or cost-effectiveness, for severe limb ischaemia due to infra-popliteal disease. Severe limb ischemia is the most severe form of lower limb peripheral artery disease and is a seriously disabling, life and limb threatening, condition. The aim of BASIL-2 is to evaluate the effectiveness and cost-effectiveness of these interventions for people with severe limb ischaemia. The BASIL-2 Trial is funded by a NIHR Health Technology Assessment grant (project number 12/35/45) Trial Progress Basil-2 officialy began its recruitment phase in July 2014 with its first randomisation from the lead centre (Heart of England NHS Foundation Trust). As of 24 Jan 2018, a total of 40 clinical centres are open to recruit to the Basil-2 trial; 29 in England, 5 in Scotland, 2 in Wales, 3 in Denmark, and 1 in Sweden. Thirty-nine of the 40 clinical centres have cumulatively recruited 256 participants. Tweets by @basil_trial BASIL-2 Trial Centres BASIL-2 Trial Centres Trial Centre Date Green Light Issued Heartlands 11/06/2014 Newcastle General 11/07/2014 Southampton 02/09/2014 Russell's Hall 29/09/2014 Hull & York Hospitals 30/09/2014 North Durham 17/10/2014 Sheffield 17/10/2014 South Manchester 21/10/2014 Aberdeen 07/11/2014 Leeds Teaching Hospital 10/11/2014 Worcester 02/12/2014 Imperial 10/12/2014 Royal Free, London 12/12/2014 Guy's and St. Thomas' 13/01/2015 Royal Cornwall 03/02/2015 UHB 06/02/2015 Sandwell & West Birmingham Hospital 09/02/2015 St George's 16/02/2015 North Cumbria 16/02/2015 Leicester 04/03/2015 Western Infirmary, Glasgow 04/03/2015 Frimley Park 09/03/2015 Royal Infirmary, Edinburgh 20/03/2015 UHCW 27/03/2015 Oxford 24/04/2015 Northwest London (Northwick Park) 28/05/2015 Manchester Royal 28/05/2015 Ninewells, Dundee (NHS Tayside) 17/06/2015 Addenbrookes 23/06/2015 Royal Bournemouth 24/07/2015 James Cook 27/07/2015 Kent & Canterbury 27/07/2015 Norfolk & Norwich 10/08/2015 Cardiff (UHW) 13/08/2015 Royal Sussex 19/08/2015 Royal Oldham 14/09/2015 Colchester General 22/09/2015 Doncaster Royal Infirmary 28/09/2015 Barts and the London 02/10/2015 York 14/10/2015 Torbay 25/11/2015 Royal Blackburn 03/12/2015 United Lincolnshire Hospitals 06/01/2016 Gloucester Hospitals 29/01/2016 Portsmouth (Queen Alexandra) 01/03/2016 Taunton 16/03/2016 Kolding (Denmark) 18/04/2016 Royal Preston 11/05/2016 Southmead (Bristol) 16/05/2016 Bradford Royal Infirmary 14/09/2016 Sodersjukhuset (sweden) 01/12/2016 Aarlborg (Denmark) 03/04/2017 Stirling (NHS Forth Valley) 04/04/2017 Odense (Denmark) 12/06/2017 You can also see our clinical centres on the map. Current BASIL-2 Recruitment (Updated 23 Feb 2018) For a more in depth overview of recruitment to BASIL-2, visit our recruitment page. Like us on Facebook!