Philip Smith

Doctoral Researcher
Physical Sciences of Imaging in the Biomedical Sciences CDT

Thesis project - "Microscopy based analyses of local membrane curvature and nanoparticle motion in Z"

Supervisors:
Dr Josh Rappoport, School of Biosciences
Professor Jon Preece, School of Chemistry
Dr Rosemary Dyson, School of Mathematics 

This project is combining live-cell fluorescence imaging with computational approaches for automated object identification and tracking to determine the routes of cellular entry and intracellular trafficking of polystyrene nanoparticles.  In particular this project is focusing on automated computational approaches for extracting localisation data for manufactured nanoparticles in live cells.