Shown here are some of the recent publications which highlight significant advances made by researchers in the Institute of Applied Health Research.
- Bhandari S, Mehta S, Khwaja A, Cleland JGF, Ives N, Brettell E, Chadburn M, Cockwell P; STOP ACEi Trial Investigators. Renin-Angiotensin System Inhibition in Advanced Chronic Kidney Disease. N Engl J Med. 2022 Dec 1;387(22):2021-2032. doi: 10.1056/NEJMoa2210639. Epub 2022 Nov 3. PMID: 36326117.
- NIHR Global Research Health Unit on Global Surgery. Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries. Lancet. 2022 Oct 31:S0140-6736(22)01884-0. doi: 10.1016/S0140-6736(22)01884-0. Epub ahead of print. PMID: 36328045.
- NIHR Global Health Unit on Global Surgery; COVIDSurg Collaborative. Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries. Lancet. 2022 Nov 5;400(10363):1607-1617. doi: 10.1016/S0140-6736(22)01846-3. Epub 2022 Oct 31. PMID: 36328042; PMCID: PMC9621702.
- Hodgetts Morton V, Toozs-Hobson P, Moakes CA, Middleton L, Daniels J, Simpson NAB, Shennan A, Israfil-Bayli F, Ewer AK, Gray J, Slack M, Norman JE, Lees C, Tryposkiadis K, Hughes M, Brocklehurst P, Morris RK. Monofilament suture versus braided suture thread to improve pregnancy outcomes after vaginal cervical cerclage (C-STICH): a pragmatic randomised, controlled, phase 3, superiority trial. Lancet. 2022 Oct 22;400(10361):1426-1436. doi: 10.1016/S0140-6736(22)01808-6. PMID: 36273481.
- Li T, Li J, Yuan L, Wu J, Jiang C, Daniels J, Mehta RL, Wang M, Yeung J, Jackson T, Melody T, Jin S, Yao Y, Wu J, Chen J, Smith FG, Lian Q; RAGA Study Investigators. Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial. JAMA. 2022 Jan 4;327(1):50-58. doi: 10.1001/jama.2021.22647. Erratum in: JAMA. 2022 Mar 22;327(12):1188. PMID: 34928310; PMCID: PMC8689436.
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Theilmann M, Lemp J M, Winkler V, Manne-Goehler J, Marcus M E, Probst C et al. Patterns of tobacco use in low and middle income countries by tobacco product and sociodemographic characteristics: nationally representative survey data from 82 countries. BMJ. 2022; 378 :e067582 doi:10.1136/bmj-2021-067582
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Subramanian A, Nirantharakumar K, Hughes S, Myles P, Williams T, Gokhale KM, et al. Symptoms and Risk Factors for Long COVID in Non-Hospitalized Adults. Nature Medicine. 2022: 1–9. doi: 10.1038/s41591-022-01909-w.
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Deeks J, Singanayagam A, Houston H, Sitch A, Hakki S, Dunning J et al. SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis. BMJ. 2022 Feb 23;376. 066871.
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Sumilo D, Nirantharakumar K, Willis BH, Rudge G, Martin J, Gokhale K et al. Long-term impact of giving prophylactic antibiotics before skin incision versus after cord clamping on children born by caesarean section: longitudinal study based on UK electronic health records. BMJ. 2022 May 17;377. e069704.
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Cruz Rivera S, Aiyegbusi OL,Ives J, Draper H, Mercieca-Bebber R, Ells C, Hunn A, Scott JA, Fernandez CV, Dickens AP, Anderson N, Bhatnagar V, Bottomley A, Campbell L, Collett C, Collis P, Craig K, Davies H, Golub R, Gosden L, Gnanasakthy A, Haf Davies, von Hildebrand M, Lord JM, Mahendraratnam N, Miyaji T ,Morel T, Monteiro J, Olsen Zwisler AD, Peipert JD, Roydhouse J, Stover AM, Wilson R, Yap C, Calvert MJ. Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical Research: The PRO Ethics Guidelines. JAMA. 2022;327(19):1910-1919. doi:10.1001/jama.2022.6421
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Hughes SE, Haroon S, Subramanian A, McMullan C, Aiyegbusi OL, Turner GM, Jackson L, Davies EH, Frost C, McNamara G, Price G, Matthews K, Camaradou J, Ormerod J, Walker A, Calvert MJ. Development and validation of the symptom burden questionnaire for long covid (SBQ-LC): Rasch analysis. BMJ. 2022 Apr 27;377:e070230. doi: 10.1136/bmj-2022-070230.
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Tucker KL, Mort S, Yu L-M, Campbell H, Rivero-Arias O, Allen J, Band R, Chisholm A, Crawford C, Dougal G, Engonidou L, Franssen M, Green M, Greenfield S, Hinton L, Hodgkinson J, Lavallee L, Leeson P, Engonidou L, Paul Leeson, McCourt C, McKillop L , Sandall J, Santos M, Tarasensenko L, Velardo C, Yardely L, Chappell LCC, McManus RJ. for the BUMP Investigators. Effect of Self-monitoring of Blood Pressure on Diagnosis of Hypertension During Higher-Risk Pregnancy: The BUMP 1 Randomized Clinical Trial. JAMA. 2022;327(17):1656–1665. doi:10.1001/jama.2022.4712
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Chappell LC, Tucker KL, Galal U, Yu L-M, Campbell H, Rivero-Arias O, Allen J, Chisholm A, Crawford C, Dougal G, Engonidou L, Franssen M, Green M, Greenfield S, Hinton L, Hodgkinson J, Lavallee L, Leeson P, Engonidou L, ; Paul Leeson, McCourt C, McKillop L , Sandall J, Santos M, Tarasensenko L, Velardo C, Wilson H, Yardley L, McManus RJ for the BUMP 2 Investigators. Effect of Self-monitoring of Blood Pressure on Blood Pressure Control in Pregnant Individuals With Chronic or Gestational Hypertension: The BUMP 2 Randomized Clinical Trial. JAMA. 2022;327(17):1666–1678 doi:10.1001/jama.2022.4726
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Lambert AM, Parretti HM, Pearce E, Price MJ, Riley M, Ryan R, Tyldesley-Marshall N, Avşar TS, Matthewman G, Lee A, Ahmed K, Odland ML, Correll CU, Solmi M, Marshall T. Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis. PLoS Med. 2022;19(4). doi:10.1371/journal.pmed.1003960