Principal publications from the Bladder Cancer Centre.
A Goel, DG Ward, NS Gordon, B Abbotts, MP Zeegers, KK Cheng, ND James, RT Bryan*, R Arnold*. Back-splicing transcript isoforms (circular RNAs) affect biologically relevant pathways and offer an additional layer of information to stratify NMIBC patients. Front Oncol 2020; 10: 812. *Joint senior authors.
DG Ward, NS Gordon, RH Boucher, SJ Pirrie, L Baxter, S Ott, L Silcock, CM Whalley, JD Stockton, A D Beggs, M Griffiths, B Abbotts, H Ijakipour, FN Latheef, R Robinson, AJ White, ND James, MP Zeegers, KK Cheng, RT Bryan. Targeted deep sequencing of urothelial bladder cancers and associated urinary DNA: a 23-gene panel with utility for non-invasive diagnosis and risk stratification. BJU Int 2019; 124: 532-544.
A Bessa, S Maclennan, D Enting, RT Bryan, D Josephs, S Hughes, S Amery, MS Khan, S Malde, R Nair, F Cahill, H Wylie, R Thurairaja, K Chatterton, N Kinsella, C Häggström, M Van Hemelrijck. Consensus in bladder cancer research priorities between patients and healthcare professionals using a four-stage modified Delphi method. Eur Urol 2019; 76: 258-259.
KIE Snell, DG Ward, NS Gordon, JC Goldsmith, AJ Sutton, P Patel, ND James, MP Zeegers, KK Cheng, RT Bryan. Exploring the role of urinary HAI-1, EpCAM & EGFR in bladder cancer prognosis and risk stratification. Oncotarget 2018; 9: 25244-253.
M Afshar, H Goodfellow, F Evison, J Parkin, RT Bryan, H Parsons, ND James, P Patel. Centralisation of radical cystectomies for bladder cancer in England a decade on from the ‘Improving Outcomes Guidance’: the case for super-centralisation. BJU Int 2018; 121: 217-224.
JJ D’Costa, JC Goldsmith, JS Wilson, RT Bryan, DG Ward. A systematic review of the diagnostic and prognostic value of urinary protein biomarkers in urothelial bladder cancer. Bladder Cancer 2016; 2: 301-17.
FS Togneri, DG Ward, JM Foster, AJ Devall, P Wojtowicz, S Alyas, F Ramos Vasques, A Oumie, ND James, KK Cheng, MP Zeegers, N Deshmukh, B O’Sullivan, P Taniere, KG Spink, DJ McMullan, M Griffiths, RT Bryan. Genomic complexity of urothelial bladder cancer revealed in urinary cfDNA. Eur J Hum Genet 2016; 24: 1167-74.
S Barnes, DET Shepherd, D Espino, RT Bryan, R Viney, P Patel. Design of an improved surgical instrument for the removal of bladder tumours. Proc Inst Mech Eng H 2016; 230: 579-87.
SC Barnes, BM Lawless, DET Shepherd, DM Espino, GR Bicknell, RT Bryan. Viscoelastic Properties of Human Bladder Tumours. J Mech Behav Biomed Mater 2016; 61: 250–257.
S Naito, F Algaba, M Babjuk, RT Bryan, YH Sun, L Valiquette, J de la Rosette on behalf of the CROES NBI Global Study Group. The Clinical Research Office of the Endourology Society (CROES) multicentre randomised trial of narrow band imaging-assisted transurethral resection (TURBT) versus conventional white light-assisted TURBT in primary non-muscle-invasive bladder cancer patients: trial protocol and 1-year results. Eur Urol 2016; 70: 506-15.
FHM van Osch, SHJ Jochems, FJan van Schooten, RT Bryan, MP Zeegers. Quantified relations between exposure to tobacco smoking and bladder cancer risk: a meta-analysis of 89 observational studies. Int J Epidemiol 2016; 45: 857-70.
RT Bryan, HL Regan, SJ Pirrie, AJ Devall, KK Cheng, MP Zeegers, ND James, MA Knowles, DG Ward. Protein shedding in urothelial bladder cancer: prognostic implications of soluble urinary EGFR and EpCAM. Br J Cancer 2015; 112: 1052-58.
SC Barnes, DET Shepherd, DM Espino, RT Bryan. Frequency Dependent Viscoelastic Properties of Porcine Bladder. J Mech Behav Biomed Mater 2015; 42: 168–176.
NJ Shimwell*, RT Bryan*, W Wei*, ND James, KK Cheng, MP Zeegers, PJ Johnson, A Martin, DG Ward. Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma. Br J Cancer 2013; 108: 1854-61. *Joint first authors.
EH van Roekel, KK Cheng, ND James, DMA Wallace, LJ Billingham, PG Murray, RT Bryan, MP Zeegers. Smoking is associated with lower age, higher grade, higher stage, and larger size of malignant bladder tumours at diagnosis. Int J Cancer 2013; 133: 446-54.
RT Bryan, SI Collins, MC Daykin, MP Zeegers, KK Cheng, DMA Wallace, GM Sole. Mechanisms of recurrence of Ta/T1 bladder cancer. Ann R Coll Surg Engl 2010; 92: 519-24.
MP Zeegers, RT Bryan, C Langford, L Billingham, P Murray, NS Deshmukh, S Hussain, N James, DMA Wallace, KK Cheng. The West Midlands Bladder Cancer Prognosis Programme: Rationale and Design. BJU Int 2010; 105: 784-88.
RT Bryan and C Tselepis. Cadherin switching and bladder cancer. J Urol 2010; 184: 423-31.
RT Bryan, LJ Billingham, DMA Wallace. Narrow band imaging flexible cystoscopy in the detection of recurrent urothelial cancer of the bladder. BJU Int 2008; 101: 702-5.
RT Bryan, J Nicholls, RF Harrison, JA Jankowski, DMA Wallace. The role of beta-catenin signalling in the malignant potential of cystitis glandularis. J Urol 2003; 170: 1892-6.
DMA Wallace, RT Bryan, JA Dunn, G Begum, S Bathers. Delay and survival in bladder cancer. BJU Int 2002; 89: 868-78.
RT Bryan and DMA Wallace. “Superficial” bladder cancer – time to uncouple pT1 tumours from pTa tumours. BJU Int 2002; 90: 846-52.