Institute of Cancer and Genomic Sciences Seminar Series

The Institute of Cancer and Genomic Sciences holds an internal seminar series each week where prestigious speakers, at both local and international level, are invited to present their research. This leads to collaborative working and a sharing of knowledge. Highlighted below are our 2022 and 2021 speakers:

2022 Speakers

 

Friday 4 November - Dr Christine Schmidt, Senior Lecturer, Division of Cancer Sciences, University of Manchester (Host: Satpal Jhujh) “Understanding and targeting genome stability mechanisms”

Friday 14 October - Dr Molly Ingersoll, Research Director, Mucosal Inflammation and Immunity Group, Institut Cochin & Institut Pasteur (Host: Professor Rik Bryan) “Dissecting immunity in the bladder”

Friday 30 September - Dr Madhu Srinivasan, Department of Biochemistry, University of Oxford (Host: Dr Sovan Sarkar)  “The Mechanism of Mitotic Chromosome Formation and Segregation”

Friday 23 September - Dr Evangelia Petsalaki,  Group Leader, European Bioinformatics Institute (EMBL-EBI) (Host: Dr Roland Arnold) Data-driven approaches towards studying context-specific cell signaling”

Friday 16 September -  Professor Kylie Gorringe, Group Leader, University of Melbourne/Peter MacCallum Cancer Centre (Host: Professor Sudha Sundar) “Mucinous ovarian carcinoma: a rare and difficult disease”

Friday 9 September - Dr Christopher Bakkenist, Professor of Radiation Oncology, University of Pittsburgh (Host: Dr Marco Saponaro) “The DNA Undamaged Response (DUR): making it possible to synthesize”

Friday 24 June -  Professor Willemien van Driel, Gynaecological Oncologist, Netherlands Cancer Institute (Host: Professor Sudha Sundar) “Current role for HIPEC in advanced ovarian carcinoma”

Thursday 9 June - Dr Mark Stoneley, Research Fellow (MRC), MRC Toxicology Unit, University of Cambridge (Host: Dr Mathew Coleman) “Stressed out RNA-binding proteins: from interaction to function” 

Friday 20 May - Dr Philip Dunne, Senior Lecturer in Molecular Pathology, in the Patrick G Johnston Centre for Cancer Research at Queen’s University Belfast (Host: Dr Roland Arnold)  “Tumour-based discovery using transcriptional data in colorectal cancer”

Friday 6 May - Dr Filipe Crriea Martins, Clinical Lecturer, Dept. of Obstetrics and Gynaecology, Cancer Research UK Cambridge Institute, University of Cambridge (Host: Professor Sudha Sundar) “Understanding chromosomal chaos to treat and prevent high-grade serous ovarian cancer”

Friday 29 April - Dr Gareth Bond, Reader, Institute of Cancer and Genomic Sciences, University of Birmingham (Host: Dr Mathew Coleman) “Pleiotropic Interactions of Rare Germline Genetic Variants found in Sarcoma and other Cancer Patients in the Genomics England Cohort”

Friday 1 April - Amanda Chaplin, Assistant Professor in Structural, Department of Molecular and Cell Biology, Leicester Institute of Structural and Chemical Biology, University of Leicester (Hosts: Dr Paloma Garcia and Dr Eva Petermann) “Cryo-EM studies of DNA-repair complexes: DNA-PK and its partners” 

Friday 25 March -  Professor Ruth RobertsChair and Director of Drug Discovery, University of Birmingham/Cofounder of ApconiX (Host: Professor Jo Parish) " Drug Discovery at UOB:  Challenges and Opportunities".

Friday 18 March - Professor Teresa Carlomagno, Professor and Academic Lead of HWB-NMR, School of Biosciences (Host: Professor Pam Kearns) “Why NMR? An integrative structural biology approach to understand functional mechanisms in biological complexes.”

Friday 11 March - Ylva Ivarsson, Professor of Biochemistry, Uppsala University, Sweden (Host:  Dr Roland Arnold)  “Proteome-scale mapping of binding sites in the intrinsically disordered regions of human and viral proteomes” 

Friday 4 March - Dr Eva Frickel, Senior Wellcome Trust Fellow/Reader, School of Biosciences, University of Birmingham (Host: Dr Sovan Sarkar) “The proto-oncogene PIM1 guards bystander cells against self-damage during infection”

Friday 18 February - Evan Noch, Assistant Professor, Division of Neuro-oncology, Department of Neurology, Weill Cornell Medicine, USA (Host: Professor Daniel Tennant) “Leveraging mitochondrial redox metabolism for treatment in glioblastoma”

Friday 11 February - Dr Robert Mahen, Cell Biologist, MRC Cancer Unit, University of Cambridge (Host: Dr Gianmarco Contino) “Exploring centrosome assembly mechanisms in healthy and cancerous cells”.

Friday 28 January - Mr Richard Wilkin, Academic Clinical Lecturer/General Surgical Registrar & Dr Elaine Leung, NIHR Academic Clinical Lecturer (Gynaecological Oncology) (Host: Professor Sudha Sundar) “Pancreatic cancer pathways and treatment- results from the first national study”.

Friday 21 January - Professor Shouqing Luo, Professor of Neurobiology, Peninsula Medical School (Faculty of Health), University of Plymouth (Host: Dr Sovan Sarkar) “Autophagy and cytotoxicity: a lesson from SQSTM1/p62 liquid droplet formation”.

Friday 14 January - Professor Ruth Roberts, Chair and Director of Drug Discovery, University of Birmingham/Cofounder of ApconiX (Host: Professor Jo Parish) " Drug Discovery at UOB:  Challenges and Opportunities".

2021 Speakers

Friday 10 December -  Dr Ben Fisher, Senior Lecturer in Clinical Rheumatology, Institute of Inflammation and Ageing and Dr Rowena Sharpe, Director of Precision Medicine Trials, CRCTU, Institute of Cancer and Genomic Sciences (Host: Professor Pam Kearns) “Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19: results from the CATALYST phase 2 proof-of-concept trial”.

Friday 3 December - Professor Abeer Shaaban, Honorary Professor Cancer and Genomic Sciences/ Consultant Pathologist at Queen Elizabeth Hospital Birmingham (Host: Professor Sudha Sundar) "Breast and ovarian cancer in women of ethnic background- What we know so far".

Friday 26 November - Dr Andreas Karwath, Senior Lecturer, Institute of Cancer and Genomic Sciences, University of Birmingham (Host: Dr Roland Arnold) "EHR Representation Learning".

Friday 19 November - Professor Terry Rabbitts, Team Leader, The Institute of Cancer Research, London (Host: Professor Conny Bonifer) "Engineering intracellular antibodies for targeted protein degradation of RAS isoforms or the LMO2 transcription complex".

Friday 12 November - Dr Joana Simoes, General Surgery trainee from Portugal/Research Fellow, NIHR Research Unit on Global Surgery, University of Birmingham (Host: Dr Sovan Sarkar) "Building an international academic career through collaborative research".

Friday 5 November - Professor Alberto Bardelli, University of Turin, Dept. of Oncology and Director of Laboratory Molecular Oncology,  Candiolo Cancer Institute, FPO-IRCCS (Host: Dr Chiara Bardella) " High dose Vitamin C and inactivation of DNA repair boost cancer immunotherapy".

Friday 22 October - Dr Viktor Korolchuk, Reader in Molecular Cell Biology, Biosciences Institute, Faculty of Medical Sciences, Newcastle University (Host: Dr Sovan Sarkar) "Nutrient response pathways: molecular mechanisms and physiological functions".

Friday 15 October - Mr Aneel Bhangu, Senior Lecturer in Surgery, University of Birmingham/Consultant Colorectal Surgeon, University Hospital Birmingham (Host: Dr Sovan Sarkar) "The FALCON RCT: A Lancet publication from the NIHR Unit on Global Surgery".

Friday 8 October - Professor Chris Buckley, Director of Clinical Research, Kennedy Institute of Rheumatology, University of Oxford (Host: Dr Fedor Berditchevski) "The implications of the human cell atlas for targeting Fibroblasts in Immune Mediated Inflammatory Diseases".

Friday 1 October - Professor Richard J. Gibbons , Weatherall Institute of Molecular Medicine, University of Oxford (Host: Dr Paloma Garcia) " Understanding a disease of chromatin."

Friday 24 September - Dr Alastair Greystoke, Clinical Senior Lecturer/Hon Consultant, Sir Bobby Robson Clinical Trials Unit Freeman Hospital, Newcastle Upon Tyne (Host: Mr Daniel Slade) "How can we personalise lung cancer treatment?  Issues in trial design and delivery."

Friday 10 September - Professor Philip M. Kim, The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Canada (Host: Dr Roland Arnold) - "Integrated development of peptide and protein therapeutics."

Friday 25 June - Professor Dr M. Cristina Cardoso, Chair of Cell Biology and Epigenetics at the Department of Biology of the Technical University of Darmstadt, Germany (Host: Dr Grant Stewart) - “Elementary units of DNA replication and repair: a mirror of chromatin higher order structure?”

Friday 11 June - Professor Syed Hussain, Professor and Honorary Consultant in Medical Oncology, University of Sheffield and Sheffield Teaching Hospitals NHS Trust (Host: Dr Rik Bryan) -  Changing landscape in the management of advanced bladder cancer.” 

Friday 4 June - Dr Alexandros Tzatsos, Associate Professor in the Department of Anatomy and Cell Biology and a member of the Cancer Center at the George Washington University School of Medicine in Washington, DC. (Host: Dr Gianmarco Contino) - “Molecular stratification and targeted therapies for pancreatic cancer.”

Friday 28 May - Dr Luke Yates, Research Associate, Department of Infectious Diseases, Imperial College London (Host: Dr Mathew Coleman) - “PIKK-ing apart the DNA damage response: how cryoEM provides a molecular view that rationalises disease mutations and drug design.” 

Friday 21 May - Dr Louise Stone, Senior Editor, Nature Reviews Urology (Host: Dr Rik Bryan) - “What editors want – the Nature of Reviews.”

Friday 14 May - Dr Deena Gendoo, Senior Lecturer in Computational Biology, Centre for Computational Biology (Host: Dr Claire Palles) - “Computational pharmacogenomics to identify cancer and subtype-specific therapies.”

Friday 7 May - Dr John Counsell,Senior Research Fellow at the UCL Great Ormond Street Institute of Child Health (Host: Professor Ferenc Mueller) - “Engineering the next generation of genomic medicines.”

Friday 30 April - Prof. Dr. med. Michael Quante,Head of Gastrointestinal Oncology,University of Freiburg, Germany (Host: Dr Claire Palles) - “Lessons from a mouse model of Barrett Esophagus – Translational opportunities in upper GI cancer.”

Friday 23 April - Dr Nicky Whiffin, Sir Henry Dale Fellow and Group Leader, Wellcome Centre for Human Genetics, University of Oxford (Host: Dr Claire Palles) - “Understanding the role of non-coding region variants in rare disease.”

Friday 26 March - Dr Ian Groves, Associate Principal Investigator, Department of Medicine, University of Cambridge (Host: Dr Jo Parish) - “Novel therapeutic strategies to abate human cytomegalovirus-mediated disease in the transplant setting.”

Friday 19 March - Professor Colin Watts, Professor of Neurosurgery, Chair Birmingham Brain Cancer Program (Host: Dr Sovan Sarkar) - “Translating the Science of Gliomas: Current Concepts & Future Challenges.” 

Friday 12 March - Professor Esther Moss, Associate Professor in Gynaecological Oncology, University of Leicester (Host: Professor Sudha Sundar) - “Endometrial cancer: The need for personalised treatment.” 

Friday 5 March - Professor Jan Jacob Schuringa, Department of Experimental Hematology, University Medical Center Groningen, University of Groningen, The Netherlands (Host: Professor Conny Bonifer) - “Dissecting clonal heterogeneity in AML.”

Friday 26 February - Professor Gerard Graham, Gardiner Chair of Immunology / Head of the Chemokine Research Group / Interim Director of the Institute of Infection, Immunity and Inflammation, University of Glasgow (Host: Dr Elaine Leung) - Atypical chemokine receptors in biology and pathology.”

Friday 12 February - Dr Kunal Rai, Associate Professor, MD Anderson Cancer Center/Scientific Director, MD Anderson Epigenomics Initiative (Host: Dr Sovan Sarkar) - “Exploiting Cancer Epigenome for Precision Medicine.”

Friday 5 February - Professor Steve Smerdon, Professor of Structural Biology, Institute of Cancer and Genomic Sciences, University of Birmingham (Host: Dr Paloma Garcia/Dr Clare Davies) - “Structural biology at the ICGS: What we are up to and how you can get involved!”

Friday 29 January - Professor Alan Parker, Professor of Translational Virotherapies, Cardiff University (Host: Dr Elaine Leung) - “From basic virology to precision virotherapies: How to train your oncolytic virus.”

Friday 22 January - Professor Marc Peschanski, Director of Research Emeritus at INSERM, Scientific Director of the I-STEM Institute, Scientific Director of the Center for Stem Cell Studies (Host: Professor Timothy Barrett) - “Harnessing pluripotent stem cells for therapies applicable to rare diseases of genetic origin.”

Friday 15 January - Dr Diu Nguyen, Cancer Biology Scientist, Memorial Sloan Kettering Institute, USA (Host: Dr Rui Monteiro) - "Understanding Post-transcriptional Regulation by RNA-Binding Proteins in Normal and Malignant Stem Cells for Novel Therapeutic Opportunities.”