Molecular Oncology, Pathology and Genetics
We are investigating the mechanisms by which cancer mutations deregulate the normal processes of cellular function and growth. We use genome-wide profiling to screen different classes of cancer, such as colorectal cancer, for potential mutations and biomarkers. We study how cancer evolves, and are developing better molecular and cellular cancer models for designing and testing new therapies.
For example, Dr Andrew Beggs’ research is looking at devising organoid models to offer personalised medicine treatments for colorectal cancer patients, and Dr Richard Bryan is developing a 23-gene panel for a non-invasive diagnosis for bladder cancer.
Dr Andrew Beggs
Reader in Surgery & Cancer Genetics