The ability to acquire a countless number of action sequences and retrieve them from memory accurately in the right context is crucial in daily life, from speech, tool use, typing and handwriting to athletic and musical performance. In each of these domains the nervous system needs to form a robust, but flexible memory of the spatio-temporal sequence involved. Several conditions affecting the pre-planning and organization of movement such as dyspraxia, stuttering and task-dependent dystonia can affect the learning, retrieval and control of skilled action sequences - with profound consequences for the individual in daily life.
The goal of the “Skilled Action & Memory” lab is threefold:
- To identify the neural basis of sequence and timing control;
- To characterize the functional plasticity related to long-term consolidation and training of skills;
- To develop entry-points for interventions that help repair or boost learning and performance in patients and the healthy population.
To address these aims, we use sequence learning paradigms in combination with neuroimaging pattern analysis (fMRI and MEG/EEG) and non-invasive neural stimulation techniques. This work is complemented by collaborations with colleagues who use computational, clinical and animal neurophysiology approaches to tackle related questions together across disciplines.
Dr Katja Kornysheva