Brief overview of the modality
The magnetic resonance imaging (MRI) laboratory houses a Siemens MAGNETOM Prisma 3T MRI system installed in December 2018. This new generation 3T MRI full body platform implements high-performance 80 mT/m gradient sets and up to 128 RF receive channels enabling high signal-to-noise and high spatial resolution head-to-toe imaging. The fast gradient system provides high-speed structural and functional imaging, the latest parallel transmit technology, simultaneous multi-slice acceleration, and high coil element density enabling increased temporal resolution and faster imaging.
The scanner is equipped with 64-Channel Head/Neck coil, 32-Channel Head coil, as well as 20-Channel coil suitable to accommodate larger patients. In addition, a full set of coils for whole-body imaging is available, including spine matrix coil and flexible matrix arrays suitable for scanning different body parts. The 64-channel coil has increased field of view enabling greater accessibility for peripheral equipment such as eye-tracking. The 64-channel allows for simultaneous EEG recordings and transcranial direct current stimulation.
The peripherals of the MRI system include:
- ProPixx visual projector (1440 Hz refresh rate)
- SOUNDPixx auditory stimulation
- SR Research Eyelink Eye tracker
- MR-compatible button boxes (NATA Response Boxes; 2x5 and 2x2)
- limb movement tracking (3 Camera Qualisys Motion Tracker System)
- Stimulus delivery computers (Psychtoolbox, PsychoPy, ePRIME and Presentation)
- Mock scanner with own projector and stimulus delivery computer
For data analysis CHBH MRI users can access Parallel Brain Imaging Cluster (PBIC), a high performance computing cluster, specifically supporting neuroimaging data analysis tools. PBIC consists of a set of RAID storage units, SGE cluster nodes and Brain Imaging Lab (BIL) workstations located in the CHBH building.
More information is available on the CHBH Intranet accessible by University of Birmingham Staff.
The mock scanner allows to train and/or acclimatize participants, particularly children and patients, to the MRI environment and advanced experimental setups.
How researchers can access equipment within modality?
To gain access on the MRI there are procedures for training, ethics and project proposals. For the procedures please see the CHBH Operating Procedures and Local Rules.
What research data is produced and what can we understand from this?
The CHBH houses several MRI research groups with particular expertise in functional MRI, diffusion MRI, arterial spin labelling and MR spectroscopy, as well as concurrent EEG-fMRI. MRI enables complex analysis of brain function and structure, including modelling of network connectivity in healthy participants and clinical populations.
How is the modality important in contributing to the CHBH values and principles?
MRI lab is at the heart of CHBH multimodal brain imaging and multidisciplinary research focused on understanding what makes our brains healthy, how to maintain brain health across lifespan, and how to prevent and reverse damage. CHBH MRI system is used for a large number of basic science and clinical studies, including several key projects investigating youth mental health, ageing, stroke recovery and mechanisms of sleep and appetite. Our scanner is used by multiple users across University of Birmingham, including researchers in all Schools inside the LES College (especially Psychology and SportExR) as well as the many collaborating Schools, Colleges and institutions outside LES (Medical School, Psychiatry, QE Hospital, Institute for Translational Medicine, Barberry National Centre for Mental Health, Birmingham Children's Hospital etc). The users of CHBH MRI lab are encouraged to conduct research in accordance with principles of open science and data sharing.
For further information, please contact the Modality Lead - Dr Madga Chechlacz