Sleep

Brief overview of the modality

CHBH-92

Our research aims to elucidate the role of sleep for cognition and behaviour. The sleep laboratory houses two sleeping suites and a central control room. For continuous sleep recordings, we use a 64-channel BrainAmp EEG system with customised EasyCap sleep caps. Each sleep suite is equipped with desktop PCs for stimulus delivery and experimental testing. External speakers are used for targeted memory reactivation (TMR) studies and closed-loop stimulation is accomplished via the OpenVibe software package.

How researchers can access equipment within modality?

To gain access to the sleep laboratories there are procedures for training, ethics and project proposals. For the procedures please see the CHBH Operating Procedures and Local Rules.

What research data is produced and what can we understand from this?

CHBH-83

The EEG system records ongoing brain activity from humans subjects while they perform cognitive tasks and while they sleep. The tasks we use include memory, motor skills, attention and language comprehension. This allows for characterizing the brain dynamics – such as neuronal oscillations – associated with a given cognitive function. During sleep, EEG is used to monitor different sleep stages online and to investigate the role of slow oscillations and sleep spindles on behaviour. Researchers at the CHBH have strong expertise in investigating the role of neuronal oscillations.

How is the modality important in contributing to the CHBH values and principles?

The sleep laboratory is used for conducting fundamental research on cognition as well as to investigate brain dynamics associated with neurological and psychiatric disorders. The data from the EEG system are complementary to data from other techniques housed in the CHBH. Therefore, we are integrating the sleep/EEG research using other techniques such as brain stimulation, functional MRI and measures of structural connectivity. The research conducted in the sleep laboratory is done in the spirit of open science and we strive to make our approaches and data freely available.

For further information, please contact the Modality Lead - Dr Bernhard Staresina