IIH Intervention Trial is a randomised clinical trial that will compare two interventions for patients with Idiopathic Intracranial Hypertension (IIH) and progressive visual loss: Cerebrospinal fluid (CSF) shunting and dural venous sinus stenting (DVSS).
Both interventions reduce intracranial pressure and preserve vision, but there has been no direct comparison between them and we still do not know which one is more effective. This is an important clinical question and the trial will change practice at national and international level. We have engaged patient groups and opinion leaders from across the country in order to design high-quality research methodology, while providing our study participants with an exceptional research experience. The trial will enrol 138 patients from 15 UK hospitals who will be randomly allocated to one of the two interventions. We will assess which one is better at preserving vision, more cost-effective, their possible complications, and their impact on headaches and on quality of life. The trial will last for 5 years and we commit to delivering patient-centred scientific research with integrity and strong ethics. Our vision is to advance knowledge, develop treatments and improve the care of patients with IIH.