MTBI Predict

Mild traumatic brain injury (mTBI), often referred to as concussion, can result in long-term disability due to persistent headaches, imbalance, memory disturbance, and poor mental health, and ~30% have not returned to work or sport at 12 months. 

mTBI-PREDICT is a long-term study that aims to identify the most accurate, reproducible and clinically practical biomarkers to better identify those at risk of long-term health issues after a head injury. This will be achieved through a harmonised program of detailed clinical phenotyping of acute mTBI patients coupled with state-of-the-art multimodal biomarker evaluation (brain imaging, fluid biomarkers, steroid hormones, visual, vestibular, and cerebral physiology). Our vision is to deliver a step change in the care of patients with mTBI and bring much needed advances in patient rehabilitation by revealing ground-breaking evidence to justify which biomarkers should be used to inform the diagnosis and early management of mTBI.