Simon Dove received his BSc from The University of Warwick in the UK and received his PhD from the University of Dundee in the UK.
He undertook Postdoctoral training in the Department of Microbiology and Molecular Genetics at Harvard Medical School in the US. He is currently an Associate Professor in the Division of Infectious Diseases at Boston Children’s Hospital and Harvard Medical School. Dr. Dove’s work focuses on the regulation of virulence gene expression in pathogenic bacteria including Pseudomonas aeruginosa and Francisella tularensis.
Pervasive targeting of nascent transcripts by Hfq in Pseudomonas aeruginosa
I will present evidence that the RNA chaperone Hfq binds hundreds of transcripts co-transcriptionally in Pseudomonas aeruginosa, sometimes in concert with another post-transcriptional regulator called Crc. Binding to nascent transcripts provides Hfq with the earliest available opportunity to exert its regulatory effects.