Additional Global Health Research

Project Leads: Professor Gregory Lip and Professor Neil Thomas

The research team in Birmingham has successfully led changes in AF management locally, in the UK, and in European countries with different healthcare systems by promoting stroke risk assessment and enabling clinicians to initiate oral anticoagulation in an integrated manner. 

The Directors have formed partnerships with three LMICs – Brazil, China and Sri Lanka. Using their knowledge and previous experience they plan to support the partners in these countries to develop tailored research to improve AF management with the aim of reducing AF-associated stroke which is common yet under-diagnosed or under-treated in these settings. 

Project Leads: Professor Rachel Jordan and Professor Peymane Adab

This NIHR Global Group, based in primary care and the community, aimed to improve the diagnosis, management and prognosis of COPD patients in low and middle income countries. Currently 90% of COPD deaths occur in low and middle-income countries (LMIC).

The Birmingham research team, working with primary care respiratory research teams in Brazil, China, Republic of North Macedonia and Georgia, and through collaboration with the IPCRG, aims to co-develop the capability, networks and platform to deliver targeted and effective research and healthcare outcomes for people with COPD.

Project Lead: Professor Arri Coomarasamy

This Bill and Melinda Gates- funded grant includes 80 secondary care health facilities in Kenya, Tanzania, Nigeria, South Africa, Sri Lanka and Pakistan are in the trial. This study has the following aims:

1. Evaluate the implementation of the E-MOTIVE intervention compared with usual care on clinical, implementation and resource use outcomes.

2. Assess the cost-effectiveness of the E-MOTIVE intervention compared with usual care from a public healthcare system perspective.

3. Develop, optimise and manualise an implementation strategy, with parallel process evaluation alongside the trial, ready for scaling-up of the E-MOTIVE intervention if found to be effective.

Our purpose is to integrate the evidence into WHO guidance for programmatic implementation of the E-MOTIVE intervention, if found to be effective, for global impact.

Project Lead: Professor Dina Kiwan

Shifting the possibilities and frame of action for humanitarian protection and human rights through research on how time conditions war, displacement, and violence.

The Disability under Siege Network Plus is a multidisciplinary project running from 2020 to 2025 and which seeks to transform the education provision for children with disabilities in conflict affected states, specifically Palestine (Gaza and West Bank), Lebanon, and Jordan.

Project Lead: Professor Heather D. Flowe

Our research delves into the extended impacts of conflict, urging policymakers and governments to recognise and act on the prolonged timelines of atrocity and recovery. Discover how our work makes a difference.

Project Lead: Professor Richard Lilford

The aim of the NIHR funded Global Health Research Unit on Improving Health in Slums is to work collaboratively to improve health service delivery in slums, benefiting the population of low and middle income countries by reducing morbidity and mortality at the population level, and doing this at the smallest possible cost to both individuals receiving health services and wider society. Working with partners in Kenya, Bangladesh, Pakistan and Nigeria, the team will map current health services and facilities and understand how these are used in seven slums across Asia and Africa. They will identify the costs associated with how the health services run in each slum. Looking to the long-term, the team will develop models of the health services with an aim to ultimately improve health service delivery.

A stepped-wedge trial of integrating depression care into routine HIV and chronic illness services in Malawi

(Part of the NIHR Global Health Research Unit on Improving Health in Slums)

Project Leads: Professor Sam Watson and Professor Richard Lilford

Integrating a Stepped Care Model of Screening and Treatment for Depression into Malawi's National HIV Care Delivery Platform. Global health trials and survey-based projects: the NIHR Global Health Research Unit on Improving Health in Slums (NIHR), a stepped-wedge trial of integrating depression care into routine HIV and chronic illness services in Malawi (NIH), the NIHR RIGHT programme on leprosy and Buruli ulcer, and a stepped-wedge trial of remote telephone consulting in Tanzania and Nigeria (NIHR/GCRF).

Full project title: Systems thinking approach to developing an integrated and patient-centred intervention model for multimorbidity care in primary care settings in India

Project Lead: Professor Semira Manaseki-Holland

The overarching goal of the study was to investigate how a systems thinking approach and causal loop modelling can support decision making in developing an integrated, patient-centred and multi-level intervention for managing multi-morbidity in primary care settings in India.

Optimal involvement of clinical and health system leadership, engagement of all potential stakeholders including patients in the intervention development are unique to this project. The key lessons from this project may help to transform the current health-care delivery system into a patient-centered and coordinated system for managing multimorbidity in primary care. 

Full project title: Development, Field-Testing and Piloting of a refractory postpartum haemorrhage management package: the PPH ReAct (PPH Refractory Action) study

Project Lead: Professor Ioannis D. Gallos

The grant, funded by Bill and Melinda Gates, is part of the Early detection and treatment of post-partum haemorrhage using the MOTIVE bundle: a World Health Organization cluster randomized trial with health economic analysis (the E-MOTIVE study) and collaborates with partners in Kenya, Tanzania, Nigeria, South Africa, Sri Lanka and Pakistan.