Dr Jane Daniels

Dr Jane Daniels

Institute of Applied Health Research
Deputy Director, Birmingham Clinical Trials Unit
Senior Research Fellow

Contact details

Birmingham Clinical Trials Unit
Institute of Applied Health Research
University of Birmingham
B15 2TT

Jane Daniels is the Deputy Director of the Birmingham Clinical Trials Unit, portfolio lead for Women’s Health clinical trials and senior research fellow in women’s health trials. Jane’s main research interest is the production of high quality evidence for health care interventions across the whole spectrum of women’s health.


  • PhD Medicine. University of Amsterdam
  • MSc Health Technology Assessment. University of Birmingham
  • MMedSci (Research) Clinical Chemistry. University of Birmingham
  • BSc (Hons) Medical Biochemistry. University of Birmingham


Graduating from the University of Birmingham in Medical Biochemistry, Jane’s early career was in molecular biology: first in allergology, then in relation to infectious diseases. She left the laboratory in 1998 and became a trial coordinator in the newly created Birmingham Clinical Trials Unit (BCTU). The first trial she coordinated was LUNA, which signalled the start of this ongoing collaboration with Professor Khalid Khan, now at Barts and the London Medical School. At that time, she was also intrinsically involved in the development of the “advice and support” function of the BCTU and collaborated with investigators from many disciplines in developing therapeutic trials in a wide range of conditions, including physiotherapy, psychiatry and neurology. Jane was the trial coordinator for the MRC funded randomised controlled trial of surgery for Parkinson’s disease. 

Jane’s main research interest is the production of high quality evidence for health care interventions across the whole spectrum of women’s health. She undertakes translational and definitive randomised controlled trials and test evaluation studies, and complements this primary research with systematic reviews and meta-analyses. Her portfolio of current research is unique in its breadth, and is outstanding in quality and impact, which has established the Birmingham Clinical Trials Unit as the leading trials unit for women’ health research in the UK. The portfolio of research in women’s health currently includes four studies preparing to recruit, nine open randomised controlled trials and three studies in follow-up or analysis. She manages a team of 15 trial management staff. She has also developed an interest in global women’s health and collaborated with the World Health Organisation on a review of the distribution of causes of maternal mortality.


  • MPH Deputy Module Coordinator for Clinical Trials
  • MBChB personal mentor 
  • BCTU’s tri-annual Research Methods Course (CPD approved)

Postgraduate supervision

Jane is interested in doctoral or MD research students in the following areas:


  • Assessing the impact of interventions for women’s health conditions
  • Development health measurement instruments and core outcome sets in women’s health

If you are interesting in studying any of these subject areas please contact Jane on the contact details above, or for any general doctoral research enquiries, please email: dr@contacts.bham.ac.uk or call +44 (0)121 414 5005.

For a full list of available Doctoral Research opportunities, please visit our Doctoral Research programme listings.   


Research themes

Evaluation of diagnostic and screening tests, randomised controlled trials of medical and surgical treatments, systematic reviews and meta-analysis, obstetrics, gynaecology and neonatalogy.

Research Activity

Other activities

  • Deputy Chair of RCOG Menstrual Disorders Clinical Studies Group
  • Affiliate of Royal College of Obstetricians and Gynaecologists
  • Member of the European Society of Gynaecological Endoscopy


Principal research publications:

  • Cooper NA, Clark TJ, Middleton L, Diwakar L, Smith P, Denny E, Roberts T, Stobert L, Jowett S, Daniels J on behalf of the OPT trial collaborative group. Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study. BMJ. 2015;350:h1398. doi: 10.1136/bmj.h1398.
  • Gupta JK, Kai J, Middleton L, Pattison H, Gray R, Daniels JP Levonorgestrel intrauterine system compared to usual medical treatment for heavy menstrual bleeding. N Eng J Med 2013;368(2):128-37
  • Daniels JP, Middleton LJ, Champaneria R, Khan KS, Cooper K, Mol BWJ, Bhattacharya S on behalf of the International Heavy Menstrual Bleeding IPD Meta-analysis Collaborative Group. Second generation endometrial ablation techniques for heavy menstrual bleeding: a network meta-analysis BMJ 2012;344:e2564
  • Ewer AK, Middleton LJ, Furmston AT, Bhoyar A, Daniels JP, Thangaratinam S, Deeks JJ, Khan KS; PulseOx Study Group. Pulse oximetry screening for congenital heart defects in newborn infants (PulseOx): a test accuracy study. Lancet. 2011 Aug 27;378(9793):785-94
  • Daniels J; Gray J, Pattison H, Roberts T, Edwards E; Milner P et al Rapid testing for GBS during labour: a test accuracy study with evaluation of acceptability and cost-effectiveness. Health Technol Assess 2009;13(42)
  • Daniels J, Gray R, Hills RK, Buckley L, Gupta JK, Latthe P, et al on behalf of the LUNA Trial Collaboration A Randomized Controlled Trial to Assess the Effectiveness of Laparoscopic Uterosacral Nerve Ablation (LUNA) for alleviating Chronic Pelvic Pain JAMA 2009;302(9):955-961