Dr Ronan Ryan

Dr Ronan Ryan

Institute of Applied Health Research
Research Fellow

Contact details

Primary Care Clinical Sciences
Institute of Applied Health Research
College of Medical and Dental Sciences
University of Birmingham
B15 2TT

Ronan is particularly interested in the use of electronic patient records for research and has over 15 years’ experience in the use of large primary care databases (CPRD/GPRD, QResearch and THIN).

His longer term aims are: 

  • to develop and make publicly available appropriate methods that will increase the accessibility and utility of large primary care databases for research; and 
  • to identify the limits of primary care databases as a data source for clinical studies, in particular for clinical prediction models.


  • PhD in General Practice: Can routinely collected primary care data be used to predict future risk of morbidity and mortality in newly-diagnosed type 2 diabetes mellitus? University of Birmingham, 2012. http://etheses.bham.ac.uk/5397
  • MSc Health Psychology, City University, London, 2000
  • MA Psychology, University College Dublin 1991
  • BA Psychology, University College Dublin, 1990


Prior to being involved in research, Ronan spent about 10 years working in the NHS and for social services as an assistant psychologist and a residential social worker in mental health, learning disabilities, and elderly services.

Since then, he has worked on the General Practice Research Database at the Office for National Statistics, on the QResearch general practice database at the University of Nottingham, and has used The Health Improvement Network (THIN) general practice database for a variety of studies while at the University of Birmingham.


  • Development of clinical prediction models using primary care data.
  • Design and analysis of case-control and cohort studies using primary care data.
  • Analysis of a stepped-wedge randomised control trial to prevent CVD in primary care.
  • Development of a method to impute missing data on ethnicity in cancer registries.


Crossan C, Lord J, Nherera L, Ryan R, Marshall T. Cost effectiveness of case-finding strategies for primary prevention of cardiovascular disease: a modelling study. British Journal of General Practice. 2016 [In press]

Turner GM, Calvert M, Feltham MG, Ryan R, Fitzmaurice D, Cheng KK, Marshall T. Under-prescribing of Prevention Drugs for the Primary Prevention of Stroke and Transient Ischemic Attack in UK General Practice: Retrospective Analysis PLOS Medicine 2016 Nov 16

Clegg A, Bates C, Young J, Ryan R, Nichols L, Teale EA, Mohammed MA, Parry J, Marshall T. Development and validation of an electronic frailty index using routine primary care electronic health record data Age and Ageing 2016 May;45(3):353-60. doi: 10.1093/ageing/afw039. Epub 2016 Mar

Martin J, Girling A, Nirantharakumar K, Ryan R, Marshall T, Hemming K. Intra-cluster and inter-period correlation coefficients for cross-sectional cluster randomised controlled trials for type-2 diabetes in UK primary care. Trials. 2016 Aug 15;17:402. doi: 10.1186/s13063-016-1532-9.

Diwakar L, Cummins C, Ryan R, Marshall T, Roberts T. Adrenaline autoinjectors for UK Children: A retrospective cohort study using The Health Improvement Network database: AAI prescriptions amongst UK children. British Journal of General Practice. 2016 [In press]

Turner GM, Calvert M, Feltham MG, Ryan R, Marshall T. Ongoing impairments following transient ischaemic attack: retrospective cohort study. European Journal of Neurology. 2016 Nov;23(11):1642-1650. doi: 10.1111/ene.13088. Epub 2016 Jul 19.

Nichols L, Ryan R, Connor C, Birchwood M, Marshall T. Derivation of a prediction model for a diagnosis of depression in young adults: a matched case-control study using electronic primary care records. Early Intervention in Psychiatry. 2016 Mar 30. doi: 10.1111/eip.12332.

Finnikin S, Ryan R, Marshall T. A cohort study investigating the relationship between cholesterol, cardiovascular risk score and the prescribing of statins in UK primary care: study protocol. BMJ Open. 2016 Nov 17;6(11):e013120.

Dube B, Ryan R, Marshall T. Predictors of human immunodeficiency virus (HIV) infection in primary care a systematic review protocol. Systematic Reviews. 2016 Sep 20;5(1):158. doi: 10.1186/s13643-016-0333-2

Marshall T, Adderley N, Ryan R. The role of contraindications in prescribing anticoagulants to atrial fibrillation patients for the prevention of stroke British Journal of General Practice. [accepted for publication]

Taylor CJ, Ryan, R, Nichols, L, Gale, N, Hobbs FDR, Marshall, T. Outcome following a first diagnostic label of heart failure in a primary care population: a survival analysis. Family Practice. [accepted for publication]