Mrs Dee Wherton

Institute of Applied Health Research
Senior Trial Manager

Contact details

Address
Birmingham Clinical Trials Unit
Public Health Building
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Dee Wherton is a Senior Trial Manager within the Women’s Health Team at the Birmingham Clinical Trials Unit (BCTU), Institute of Applied Health Research at the University of Birmingham.

Dee is responsible for the setup and coordination of the iHOLDS Trial: a double-blind randomised controlled trial of high or low dose oxytocin for induction of labour in nulliparous women.

Biography

After working in research within rheumatology, haematology and oncology research in the NHS, Dee joined the Cancer Research UK Clinical Trials Unit (CRCTU) as a Trial Coordinator in the Children’s Cancer Trials Team where she opened the CRCTU’s first international paediatric trial sponsored by the University, BEACON-Neuroblastoma.

Dee moved to the Early Drug Development Team at CRCTU in 2014 as a Senior Trial Coordinator, setting up and providing senior oversight for the day-to-day running of the National Lung Matrix Trial, the world’s largest precision medicine for non-small cell lung cancer.

Dee moved to the BCTU in 2020 to work on the HOLDS and iHOLDS trials: multicentre, randomised, double-blind controlled trials to evaluate the effect on caesarean section rate of high versus standard dose oxytocin for nulliparous women at term for either delay or induction of labour.  (iHOLDS@trials.bham.ac.uk)

Teaching

Research

Contribution to the following BCTU clinical trials:

Contribution to the following CRCTU clinical trials:

Publications

Middleton G, Fletcher P, Popat S, Savage J, Summers Y, Greystoke A, Gilligan D, Cave J, O’Rourke N, Brewster A, Toy E, Spicer J, Jain P, Dangoor A, Mackean M, Forster M, Farley A, Wherton D, Mehmi M, Sharpe R, Mills T, Cerone M, Yap T, Watkins T, Lim E, Swanton C, Billingham L. The National Lung Matrix Trial of personalised therapy in lung cancer Nature 2020;583:807-812 https://www.nature.com/articles/s41586-020-2481-8 

Middleton G, Crack LR, Popat S, Swanton C, Hollingsworth SJ, Buller R, Walker I, Carr TH, Wherton D, Billingham LJ. The National Lung Matrix Trial: translating the biology of stratification in advanced on-small cell lung cancer Annals of Oncology 2015;26(12):2464-9 https://pubmed.ncbi.nlm.nih.gov/26410619/ 

Bailey S, Howman A, Wheatley K, Wherton D, Boota N, Pizer B, Fisher D, Kearns P, Picton S, Saran F, Gibson M, Glaser A, Connolly D, Hargrave D.  Diffuse Intrinsic Pontine Glioma treated with prolonged temozolomide and radiotherapy – results of the United Kingdom Trial (CNS 2007 04) European Journal of Cancer 2013;49(1):3856-3862 https://pubmed.ncbi.nlm.nih.gov/24011536/

Bailey S, Howman A, Pizer B, Harris D, Jones D, Kearns P, Picton S, Saran F, Wheatley K, Gibson M, Glaser A, Connolly D, Hargrave D.  Diffuse Intrinsic Pontine Glioma treated with prolonged temozolomide and radiotherapy – results of the United Kingdom Trial (CNS 2007 04) Neuro-Oncology (2012);14(1):27