Recent publications
Article
Harding, C, Cadby, I, Moynihan, P & Lovering, A 2021, 'A rotary mechanism for allostery in bacterial hybrid malic enzymes', Nature Communications, vol. 12, no. 1, 1228. https://doi.org/10.1038/s41467-021-21528-2
Harding, CJ, Huwiler, SG, Somers, H, Lambert, C, Ray, LJ, Till, R, Taylor, G, Moynihan, PJ, Sockett, RE & Lovering, AL 2020, 'A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus', Nature Communications, vol. 11, no. 1, 4817 . https://doi.org/10.1038/s41467-020-18139-8
Burke, C, Jankute, M, Moynihan, P, Gonzalez Del Rio, R, Li, X, Esquivias, J, Lelièvre, J, Cox, JAG, Sacchettini, J & Besra, GS 2020, 'Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline', FASEB BioAdvances, vol. 2, no. 10, pp. 600-612. https://doi.org/10.1096/fba.2020-00022
Preciado-Llanes, L, Aulicino, A, Canals, R, Moynihan, PJ, Zhu, X, Jambo, N, Nyirenda, TS, Kadwala, I, Sousa Gerós, A, Owen, SV, Jambo, KC, Kumwenda, B, Veerapen, N, Besra, GS, Gordon, MA, Hinton, JCD, Napolitani, G, Salio, M & Simmons, A 2020, 'Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease', Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.2007472117
Cadby, IT, Basford, SM, Nottingham, R, Meek, R, Lowry, R, Lambert, C, Tridgett, M, Till, R, Ahmad, R, Fung, R, Hobley, L, Hughes, WS, Moynihan, PJ, Sockett, RE & Lovering, A 2019, 'Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase.', The EMBO journal, vol. 38, no. 15, e100772. https://doi.org/10.15252/embj.2018100772
Meek, RW, Cadby, IT, Moynihan, PJ & Lovering, AL 2019, 'Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio', Nature Communications, vol. 10, no. 1, 4086 . https://doi.org/10.1038/s41467-019-12051-6
Moynihan, PJ, Cadby, IT, Veerapen, N, Jankute, M, Crosatti, M, Mukamolova, GV, Lovering, AL & Besra, GS 2019, 'The hydrolase LpqI primes mycobacterial peptidoglycan recycling', Nature Communications, vol. 10, no. 1, 2647. https://doi.org/10.1038/s41467-019-10586-2
Kharkwal, SS, Veerapen, N, Jervis, P, Bhowruth, V, Besra, AK, North, SJ, Haslam, SM, Dell, A, Hobrath, J, Quaid, P, Moynihan, P, Cox, LR, Kharkwal, H, Zauderer, M, Besra, GS & Porcelli, SA 2018, 'Photoactivable glycolipid antigens generate stable conjugates with CD1d for invariant Natural Killer T cell activation', Bioconjugate Chemistry. https://doi.org/10.1021/acs.bioconjchem.8b00484
Turapov, O, Forti, F, Kadhim, B, Ghisotti, D, Sassine, J, Straatman-Iwanowska, A, Bottrill, AR, Moynihan, PJ, Wallis, R, Barthe, P, Cohen-Gonsaud, M, Ajuh, P, Vollmer, W & Mukamolova, GV 2018, 'Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis', Cell Reports, vol. 25, no. 1, pp. 57-67.e5. https://doi.org/10.1016/j.celrep.2018.09.004
Moynihan, P & Besra, G 2017, 'Colworth prize lecture 2016: exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery', Microbiology, vol. 163, no. 10. https://doi.org/10.1099/mic.0.000522
Sychantha, D, Jones, CS, Little, DJ, Moynihan, PJ, Robinson, H, Galley, NF, Roper, DI, Dowson, CG, Howell, PL & Clarke, AJ 2017, 'In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA)', PLoS pathogens, vol. 13, no. 10, pp. e1006667. https://doi.org/10.1371/journal.ppat.1006667
Abrahams, KA, Cox, JAG, Fütterer, K, Rullas, J, Ortega-Muro, F, Loman, NJ, Moynihan, PJ, Pérez-Herrán, E, Jiménez, E, Esquivias, J, Barros, D, Ballell, L, Alemparte, C & Besra, GS 2017, 'Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface', Scientific Reports, vol. 7, no. 1, 9430. https://doi.org/10.1038/s41598-017-09642-y
Abrahams, KA, Chung, C-W, Ghidelli-Disse, S, Rullas, J, Rebollo-López, MJ, Gurcha, SS, Cox, JAG, Mendoza, A, Jiménez-Navarro, E, Martínez-Martínez, MS, Neu, M, Shillings, A, Homes, P, Argyrou, A, Casanueva, R, Loman, NJ, Moynihan, PJ, Lelièvre, J, Selenski, C, Axtman, M, Kremer, L, Bantscheff, M, Angulo-Barturen, I, Izquierdo, MC, Cammack, NC, Drewes, G, Ballell, L, Barros, D, Besra, GS & Bates, RH 2016, 'Identification of KasA as the cellular target of an anti-tubercular scaffold', Nature Communications, vol. 7, 12581. https://doi.org/10.1038/ncomms12581, https://doi.org/10.1038/ncomms12581
Letter
Moynihan, PJ 2018, 'The lasting impact of the 2013 beveridge poster award', Canadian Journal of Microbiology, vol. 64, no. 9, pp. 645-645. https://doi.org/10.1139/cjm-2017-0458
Other contribution
Itabangi, H, Sephton-Clark, PCS, Zhou, X, Insua, I, Probert, M, Correia, J, Moynihan, P, Gebremariam, T, Gu, Y, Lin, L, Ibrahim, AS, Brown, GD, King, JS, Trillo, FF, Ballou, ER & Voelz, K 2019, A bacterial endosymbiont enables fungal immune evasion during fatal mucormycete infection.. https://doi.org/10.1101/584607
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