Kristian is a principal statistician at the Cancer Research UK Clinical Trials Unit. He joined in 2014, with a focus on early phase trials in haematology and lung cancer. In 2016 he joined the D3B team at the Institute of Translational Medicine, with an exclusive focus on early phase and translational clinical research.
His overriding research interest is efficient methods for clinical trials with small sample sizes. This entails Bayesian statistical modelling, repeated measures, incorporating predictive information in biomarkers, dose-finding methodology, seamless phase I/II methodology, and methods for rare diseases. He is currently researching a PhD on efficient methods for clinical trials.
He is a co-investigator in clinical trials in Wolfram syndrome, chronic lymphocytic leukaemia (CLL), Crohn’s disease, ALS, trauma, dry-eye disease, and burns. He has previously worked on trials in AML, MDS, CML, lymphoma, myeloma, and merkel cell carcinoma.