Kristian is a principal statistician at the Cancer Research UK Clinical Trials Unit. He joined in 2014, with a focus on early phase trials in haematology and lung cancer. In 2016 he joined the D3B team at the Institute of Translational Medicine, with an exclusive focus on early phase and translational clinical research.
His overriding research interest is efficient methods for clinical trials with small sample sizes. This entails Bayesian statistical modelling, repeated measures, incorporating predictive information in biomarkers, dose-finding methodology, seamless phase I/II methodology, and methods for rare diseases. He obtained a PhD on efficient methods for clinical trials in 2019.
He is a co-investigator in clinical trials in lung cancer, leukaemia, Wolfram syndrome, Crohn’s disease, ALS, trauma, dry-eye disease, and burns. He has previously worked on trials in lymphoma, myeloma, and merkel cell carcinoma.