Dr Christopher Middleton

Dr Christopher Middleton

Institute of Cancer and Genomic Sciences
Research Fellow

Contact details

Address
Centre for Computational Biology
Institute of Cancer and Genomic Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT

My research interests are in using next generation sequencing to investigate chromatin structure, transcription factor binding and gene expression during cell differentiation. This enables us to gain an insight into the changes that occur within the genome when cells go through differentiation.

Qualifications

  • PhD ‘Evolution and genome dynamics of cereal grasses’ University of Zurich, 2013
  • MSc ‘Plant genetics and crop improvement’ University of East Anglia, 2009
  • BSc (Hons) 'Molecular Genetics' University of Sussex, 2005

Publications

Siddiqui, N., Middleton, C., Ribeiro, C., Atan, S. and Di Cola, A. (2017). Gel-based proteomic study for differential expression of Hevea brasiliensis root proteins in response to infection by soil fungus Rigidoporus microporus. Acta Hortic. 1152, 229-234

Mohammad Pourkheirandish, Goetz Hensel, Benjamin Kilian, Natesan Senthil, Guoxiong Chen, Mohammad Sameri, Perumal Azhaguvel, Shun Sakuma, Sidram Dhanagond, Rajiv Sharma, Martin Mascher, Axel Himmelbach, Sven Gottwald, Sudha K. Nair, Akemi Tagiri, Fumiko Yukuhiro, Yoshiaki Nagamura, Hiroyuki Kanamori, Takashi Matsumoto, George Willcox, Christopher P. Middleton, Thomas Wicker, Alexander Walther, Robbie Waugh, Geoffrey B. Fincher, Nils Stein, Jochen Kumlehn, Kazuhiro Sato, Takao Komatsuda, Evolution of the Grain Dispersal System in Barley, Cell, Volume 162, Issue 3, 2015, Pages 527-539


Middleton CP, Senerchia N, Stein N, Akhunov ED, Keller B, et al. (2014) Sequencing of Chloroplast Genomes from Wheat, Barley, Rye and Their Relatives Provides a Detailed Insight into the Evolution of the Triticeae Tribe. PLOS ONE 9(3)

Jizeng Jia, Shancen Zhao, Xiuying Kong, Yingrui Li, Guangyao Zhao, Weiming He, Rudi Appels, Matthias Pfeifer, Yong Tao, Xueyong Zhang, Ruilian Jing, Chi Zhang, Youzhi Ma, Lifeng Gao, Chuan Gao, Manuel Spannagl, Klaus F. X. Mayer, Dong Li, Shengkai Pan, Fengya Zheng, Qun Hu, Xianchun Xia, Jianwen Li, Qinsi Liang, Jie Chen, Thomas Wicker, Caiyun Gou, Hanhui Kuang, Genyun He, Yadan Luo , Beat Keller, Qiuju Xia, Peng Lu, Junyi Wang, Hongfeng Zou, Rongzhi Zhang, Junyang Xu, Jinlong Gao, Christopher Middleton, Zhiwu Quan, Guangming Liu, Jian Wang, International Wheat Genome Sequencing Consortium, Huanming Yang,, Xu Liu, Zhonghu He, Long Mao, Jun Wang, Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation (2013), Nature, 496, 91-95

Middleton, C. P., Stein, N., Keller, B., Kilian, B. and Wicker, T. (2013), Comparative analysis of genome composition in Triticeae reveals strong variation in transposable element dynamics and nucleotide diversity. Plant J, 73: 347–356

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