Prior to her current role which commenced 1st October 2019, Dr Sharpe was the Head of Precision Medicine at Cancer Research UK, where she had responsibility for leading on the Charity’s agenda in this area and delivering on/evolving the CRUK Stratified Medicine Programme (SMP). The CRUK SMP is a nation-wide genomic screening study which both determines trial eligibility but also aims to improve sample standards, performance of genomic sequencing and the utilisation of these results across the UK as a whole.
Prior to this, Dr Sharpe worked at the Royal Marsden NHS Foundation Trust as their NIHR BRC Assistant Director where she set up a new method for awarding and monitoring funding internally, set up the new Royal Marsden Clinical Trials Unit, oversaw the Generic Biobank and led on Royal Marsden involvement in initiatives such as Genomics England.
Dr Sharpe has also carried out large change programmes, for example with the Children’s Cancer and Leukaemia Group (CCLG), overseen the management of early phase trial grants and carried out several strategic reviews at CRUK, including the future of biomarker-driven clinical trials.