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Khan, AO, Rodriguez-Romera, A, Reyat, JS, Olijnik, AA, Colombo, M, Wang, G, Wen, WX, Sousos, N, Murphy, LC, Grygielska, B, Perrella, G, Mahony, CB, Ling, RE, Elliott, NE, Karali, CS, Stone, AP, Kemble, S, Cutler, EA, Fielding, AK, Croft, AP, Bassett, D, Poologasundarampillai, G, Roy, A, Gooding, S, Rayes, J, Machlus, KR & Psaila, B 2023, 'Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies', Cancer Discovery, vol. 13, no. 2, pp. 364-385. https://doi.org/10.1158/2159-8290.CD-22-0199
Schrottmaier, WC, Pirabe, A, Pereyra, D, Heber, S, Hackl, H, Schmuckenschlager, A, Brunnthaler, L, Santol, J, Kammerer, K, Oosterlee, J, Pawelka, E, Treiber, SM, Khan, AO, Pugh, M, Traugott, MT, Schörgenhofer, C, Seitz, T, Karolyi, M, Jilma, B, Rayes, J, Zoufaly, A & Assinger, A 2022, 'Platelets and antiplatelet medication in COVID-19-related thrombotic complications', Frontiers in cardiovascular medicine, vol. 8, 802566. https://doi.org/10.3389/fcvm.2021.802566
Khan, A, Reyat, J, Hill, H, Bourne, J, Colicchia, M, Newby, ML, Allen, JD, Crispin, M, Youd, E, Murray, P, Taylor, G, Stamataki, Z, Richter, A, Cunningham, A, Pugh, M & Rayes, J 2022, 'Preferential uptake of SARS-CoV-2 by pericytes potentiates vascular damage and permeability in an organoid model of the microvasculature', Cardiovascular Research, pp. 1-12. https://doi.org/10.1093/cvr/cvac097
Colicchia, M, Schrottmaier, WC, Perrella, G, Reyat, JS, Begum, J, Slater, A, Price, J, Clark, JC, Zhi, Z, Simpson, M, Bourne, J, Poulter, NS, Khan, AO, Nicolson, PLR, Pugh, MR, Harrison, P, Iqbal, AJ, Rainger, GE, Watson, SP, Thomas, MR, Mutch, NJ, Assinger, A & Rayes, J 2022, 'S100A8/A9 drives the formation of procoagulant platelets through GPIbα', Blood. https://doi.org/10.1182/blood.2021014966
Krysko, O, Bourne, J, Kondakova, E, Galova, E, Whitworth, K, Newby, ML, Bachert, C, Hill, H, Crispin, M, Stamataki, Z, Cunningham, A, Pugh, M, Khan, A, Rayes, J, Vedunova, M, Krysko, D & Brill, A 2022, 'Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation', Frontiers in immunology, vol. 13, 968981. https://doi.org/10.3389/fimmu.2022.968981
Lacey, J, Webster, SJ, Heath, P, Hill, CJ, Nicholson-Goult, L, Wagner, B, Khan, A, Morgan, N, Makris, M & Daly, ME 2022, 'Sorting Nexin 24 is required for α-granule biogenesis and cargo delivery in megakaryocytes', Haematologica, vol. 2022, no. 8, 279636, pp. 1902-1913. https://doi.org/10.3324/haematol.2021.279636
Hansjosten, I, Takamiya, M, Rapp, J, Reiner, L, Fritsch-Decker, S, Mattern, D, Andraschko, S, Anders, C, Pace, G, Dickmeis, T, Peravali, R, Rastegar, S, Strähle, U, Hsiao, IL, Gilliland, D, Ojea-Jimenez, I, Ambrose, SVY, Belinga-Desaunay-Nault, MFA, Khan, AO, Lynch, I, Valsami-Jones, E, Diabaté, S & Weiss, C 2022, 'Surface functionalisation-dependent adverse effects of metal nanoparticles and nanoplastics in zebrafish embryos', Environmental Science: Nano, vol. 9, no. 1, pp. 375-392. https://doi.org/10.1039/d1en00299f
Schrottmaier, WC, Pirabe, A, Pereyra, D, Heber, S, Hackl, H, Schmuckenschlager, A, Brunnthaler, L, Santol, J, Kammerer, K, Oosterlee, J, Pawelka, E, Treiber, SM, Khan, AO, Pugh, M, Traugott, MT, Schörgenhofer, C, Seitz, T, Karolyi, M, Jilma, B, Rayes, J, Zoufaly, A & Assinger, A 2021, 'Adverse outcome in COVID-19 is associated with an aggravating hypo-responsive platelet phenotype', Frontiers in cardiovascular medicine, vol. 8, 795624. https://doi.org/10.3389/fcvm.2021.795624
Pike, J, Simms, V, Smith, C, Morgan, N, Khan, A, Poulter, N, Styles, I & Thomas, S 2021, 'An adaptable analysis workflow for characterization of platelet spreading and morphology', Platelets, vol. 32, no. 1, pp. 54-58. https://doi.org/10.1080/09537104.2020.1748588
Stapley, R, Smith, C, Haining, E, Bacon, A, Lax, S, Pisareva, V, Pisarev, A, Watson, S, Khan, A & Morgan, N 2021, 'Heterozygous mutation SLFN14 K208N in mice mediates species-specific differences in platelet and erythroid lineage commitment: SLFN14 mediates lineage commitment in mice', Blood Advances, vol. 5, no. 2, pp. 377–390. https://doi.org/10.1182/bloodadvances.2020002404
Nicolson, P, Nock, SH, Hinds, J, Garcia Quintanilla, L, Smith, C, Campos, J, Brill, A, Pike, J, Khan, A, Poulter, N, Kavanagh, D, Watson, S, Watson, CN, Clifford, H, Huissoon, A, Pollitt, A, Eble, JA, Pratt, D, Watson, S & Hughes, C 2021, 'Low-dose Btk inhibitors selectively block platelet activation by CLEC-2', Haematologica, vol. 106, no. 1, pp. 208-219. https://doi.org/10.3324/haematol.2019.218545
Campos, J, Ponomaryov, T, De Prendergast, A, Whitworth, K, Smith, C, Khan, A, Kavanagh, D & Brill, A 2021, 'Neutrophil extracellular traps and inflammasomes cooperatively promote venous thrombosis in mice', Blood Advances, vol. 5, no. 9, pp. 2319–2324. https://doi.org/10.1182/bloodadvances.2020003377
UK GAPP Study Group 2021, 'Novel gene variants in patients with platelet-based bleeding using combined exome sequencing and RNAseq murine expression data', Journal of Thrombosis and Haemostasis, vol. 19, no. 1, pp. 262-268. https://doi.org/10.1111/jth.15119
The UK GAPP Study Group, Stapley, R, Poulter, N, Khan, A, Smith, C, Bignell, P, Fratter, C, Lester, W, Lowe, G & Morgan, N 2021, 'Rare missense variants in Tropomyosin-4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects and excessive bleeding', Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15584
Almazni, IAF, Stapley, R, Khan, A & Morgan, N 2020, 'A comprehensive bioinformatic analysis of 126 patients with an inherited platelet disorder to identify both sequence and copy number genetic variants', Human Mutation, vol. 41, no. 11, pp. 1848-1865. https://doi.org/10.1002/humu.24114
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