Recent publications
Article
Stapley, R, Smith, C, Haining, E, Bacon, A, Lax, S, Pisareva, V, Pisarev, A, Watson, S, Khan, A & Morgan, N 2021, 'Heterozygous mutation SLFN14 K208N in mice mediates species-specific differences in platelet and erythroid lineage commitment: SLFN14 mediates lineage commitment in mice', Blood Advances, vol. 5, no. 2, pp. 377–390. https://doi.org/10.1182/bloodadvances.2020002404
Nicolson, P, Nock, SH, Hinds, J, Garcia Quintanilla, L, Smith, C, Campos, J, Brill, A, Pike, J, Khan, A, Poulter, N, Kavanagh, D, Watson, S, Watson, CN, Clifford, H, Huissoon, A, Pollitt, A, Eble, JA, Pratt, D, Watson, S & Hughes, C 2021, 'Low-dose Btk inhibitors selectively block platelet activation by CLEC-2', Haematologica, vol. 106, no. 1, pp. 208-219. https://doi.org/10.3324/haematol.2019.218545
Campos, J, Ponomaryov, T, De Prendergast, A, Whitworth, K, Smith, C, Khan, A, Kavanagh, D & Brill, A 2021, 'Neutrophil extracellular traps and inflammasomes cooperatively promote venous thrombosis in mice', Blood Advances, vol. 5, no. 9, pp. 2319–2324. https://doi.org/10.1182/bloodadvances.2020003377
UK GAPP Study Group 2021, 'Novel gene variants in patients with platelet-based bleeding using combined exome sequencing and RNAseq murine expression data', Journal of Thrombosis and Haemostasis, vol. 19, no. 1, pp. 262-268. https://doi.org/10.1111/jth.15119
Almazni, IAF, Stapley, R, Khan, A & Morgan, N 2020, 'A comprehensive bioinformatic analysis of 126 patients with an inherited platelet disorder to identify both sequence and copy number genetic variants', Human Mutation, vol. 41, no. 11, pp. 1848-1865. https://doi.org/10.1002/humu.24114
Pike, J, Simms, V, Smith, C, Morgan, N, Khan, A, Poulter, N, Styles, I & Thomas, S 2020, 'An adaptable analysis workflow for characterization of platelet spreading and morphology', Platelets. https://doi.org/10.1080/09537104.2020.1748588 Abstract
Khan, A, Maclachlan, A, Lowe, G, Nicolson, P, Al Ghaithi, RHR, Thomas, S, Watson, S, Pike, J & Morgan, N 2020, 'High-throughput platelet spreading analysis: a tool for the diagnosis of platelet-based bleeding disorders', Haematologica, vol. 105, pp. e124-e128. https://doi.org/10.3324/haematol.2019.225912
Khan, A, Slater, A, Maclachlan, A, Nicolson, P, Pike, J, Reyat, J, Yule, J, Stapley, R, Rayes, J, Thomas, S & Morgan, N 2020, 'Post-translational polymodification of β1-tubulin regulates motor protein localisation in platelet production and function', Haematologica, vol. 2020, no. 00, pp. 1-43. https://doi.org/10.3324/haematol.2020.270793
Khan, AO, Maio, AD, Guggenheim, EJ, Chetwynd, AJ, Pencross, D, Tang, S, Belinga-Desaunay, M-FA, Thomas, SG, Rappoport, JZ & Lynch, I 2020, 'Surface chemistry-dependent evolution of the nanomaterial corona on TiO2 nanomaterials following uptake and sub-cellular localization', Nanomaterials, vol. 10, no. 3, 401. https://doi.org/10.3390/nano10030401
Pike, J, Khan, A, Pallini, C, Thomas, S, Mund, M, Ries, J, Poulter, N & Styles, I 2020, 'Topological data analysis quantifies biological nano-structure from single molecule localization microscopy', Bioinformatics, vol. 36, no. 5, pp. 1614–1621. https://doi.org/10.1093/bioinformatics/btz788
Khan, A, White, CW, Pike, J, Yule, J, Slater, A, Hill, SJ, Poulter, N, Thomas, S & Morgan, N 2019, 'Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in', Scientific Reports, vol. 9, no. 1, 14219. https://doi.org/10.1038/s41598-019-50733-9
Hansjosten, I, Rapp, J, Reiner, L, Vatter, R, Fritsch-Decker, S, Peravali, R, Palosaari, T, Joossens, E, Gerloff, K, Macko, P, Whelan, M, Gilliland, D, Ojea-Jimenez, I, Monopoli, MP, Rocks, L, Garry, D, Dawson, K, Röttgermann, PJF, Murschhauser, A, Rädler, JO, Tang, SVY, Gooden, P, Belinga-Desaunay, M-FA, Khan, AO, Briffa, S, Guggenheim, E, Papadiamantis, A, Lynch, I, Valsami-Jones, E, Diabaté, S & Weiss, C 2018, 'Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines', Archives of toxicology, vol. 92, no. 2, pp. 633-649. https://doi.org/10.1007/s00204-017-2106-7
Morgan, N, Fletcher, S, Khan, A, Pisarev, A, Pisareva, V & Tcherepanov, A 2018, 'Role of the novel endoribonuclease SLFN14 and its disease causing mutations in ribosomal degradation', RNA, vol. 24, no. 7, pp. 939-949. https://doi.org/10.1261/rna.066415.118
Chapter
Poulter, N, Khan, A, Pallini, C & Thomas, S 2018, Single molecule localisation and structured illumination microscopy of platelet proteins. in Platelets and megakaryocytes: volume 4, advanced protocols and perspectives. vol. 4, Methods in Molecular Biology, vol. 1812, Humana Press. https://doi.org/10.1007/978-1-4939-8585-2
Review article
Khan, A & Pike, J 2020, 'Super-resolution imaging and quantification of megakaryocytes and platelets', Platelets. https://doi.org/10.1080/09537104.2020.1732321
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