Professor John S. Fossey

Professor John Fossey

School of Chemistry
Professor of Synthetic Chemistry
International Representative for Chemistry

Contact details

Telephone
+44 (0) 121 414 8907
Email
j.s.fossey@bham.ac.uk
View my research portal
Address
School of Chemistry
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Website: www.johnfossey.com

Qualifications

  • Oct 2000 - Dec 2003 PhD with Dr Christopher J. Richards at Queen Mary University of London
  • Oct 1996 - June 2000 MChem at Cardiff University of Wales
John's full professional profile can be found at www.johnfossey.com/group/jsf

Biography

Professor John S. Fossey (orcid.org/0000-0002-2626-5117) has been a Royal Society Industry Fellow, he has four granted patents and just over 100 peer-reviewed publications. Expertise in synthesis applied to sensing, catalysis and drug discovery. Among several research projects in catalysis and sensing for health and sustainability he has recently begun to tackle drug delivery for type 1 diabetes management. Furthermore, he is working closely with the Guangzhou Institutes of Biomedical Health (GIBH) and collaborators at the University of Birmingham to translate synthetic chemistry and methodology development into new therapies for tuberculosis. 

Professor Fossey has secured funding from multiple organisations including the Leverhulme Trust, the Royal Society, the JDRF, the EPSRC, EU H2020, the Sasakawa Foundation, the JSPS and the National Natural Science Foundation China. He is a visiting Professor at Henan Normal University, a Guest Professor East China University of Science and Technology and a Guest Lecturer at Sun Yat-sen University. Professor John Fossey was part of the team that won the 2013 Daiwa Adrian prize for UK-Japan collaborative research and he is the inaugural Czarnik Emerging Investigator Prize winner. 

Research

Research Interests

  • Multi-component, atom economic organic synthesis
  • Chiral induction in molecular processes
  • Cation π-stacking
  • Carbohydrate and glycoconjugate recognition
  • Carbohydrate analytical chemistry

Detailed information can be found on John's ResearcherID profile.

Publications

Recent publications

Article

Williams, GT, Kedge, JL & Fossey, JS 2021, 'Molecular boronic acid-based saccharide sensors', ACS Sensors, vol. 6, no. 4, pp. 1508–1528. https://doi.org/10.1021/acssensors.1c00462

Quy, A, Li, X, Male, L, Stankovic, T, Agathanggelou, A & Fossey, J 2020, 'Aniline-containing derivatives of parthenolide: Synthesis and anti-chronic lymphocytic leukaemia activity', Tetrahedron, vol. 76, no. 48, 131631. https://doi.org/10.1016/j.tet.2020.131631

Payne, DT, Webre, WA, Gobeze, HB, Seetharaman, S, Matsushita, Y, Karr, PA, Chahal, MK, Labuta, J, Jevasuwan, W, Fukata, N, Fossey, JS, Ariga, K, D'Souza, F & Hill, JP 2020, 'Nanomolecular singlet oxygen photosensitizers based on hemiquinonoid-resorcinarenes, the fuchsonarenes', Chemical Science, vol. 11, no. 10, pp. 2614-2620. https://doi.org/10.1039/d0sc00651c

Xu, S, Sedgwick, A, Elfeky, S, Chen, W, Jones, A, Williams, G, Jenkins, T, Bull, S, Fossey, J & James, T 2019, 'A boronic acid-based fluorescent hydrogel for monosaccharide detection', Frontiers of Chemical Science and Engineering, vol. 2020, pp. 112-116. https://doi.org/10.1007/s11705-019-1812-5

Hadzhiev, Y, Qureshi, HK, Wheatley, L, Cooper, L, Jasiulewicz, A, Van Nguyen, H, Wragg, JW, Poovathumkadavil, D, Conic, S, Bajan, S, Sik, A, Hutvàgner, G, Tora, L, Gambus, A, Fossey, JS & Müller, F 2019, 'A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation', Nature Communications, vol. 10, no. 1, 691, pp. 691. https://doi.org/10.1038/s41467-019-08487-5

Zhao, Y, Wakeling, M, Meloni, F, Sum, TJ, Nguyen, VH, Buckley, BR, Davies, P & Fossey, J 2019, 'Balancing bulkiness in gold(I) phosphino-triazole catalysis', European Journal of Organic Chemistry, vol. 2019, no. 31-32, pp. 5540-5548. https://doi.org/10.1002/ejoc.201900850

Brittain, WDG, Dalling, AG, Sun, Z, Duff, CSL, Male, L, Buckley, BR & Fossey, JS 2019, 'Coetaneous catalytic kinetic resolution of alkynes and azides through asymmetric triazole formation', Scientific Reports, vol. 9, no. 1, 15086. https://doi.org/10.1038/s41598-019-50940-4

Li, X, Payne, DT, Ampolu, B, Bland, N, Brown, JT, Dutton, MJ, Fitton, CA, Gulliver, A, Hale, L, Hamza, D, Jones, G, Lane, R, Leach, AG, Male, L, Merisor, EG, Morton, MJ, Quy, A, Roberts, R, Scarll, R, Schulz-utermoehl, T, Stankovic, T, Stevenson, B, Fossey, JS & Agathanggelou, A 2019, 'Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia', Medchemcomm, vol. 10, no. 8, pp. 1379-1390. https://doi.org/10.1039/C9MD00297A

Payne, DT, Webre, WA, Matsushita, Y, Zhu, N, Futera, Z, Labuta, J, Jevasuwan, W, Fukata, N, Fossey, JS, D’Souza, F, Ariga, K, Schmitt, W & Hill, JP 2019, 'Multimodal switching of a redox-active macrocycle', Nature Communications, vol. 10, 1007 . https://doi.org/10.1038/s41467-019-08978-5

Yoshizawa, A, Feula, A, Leach, AG, Male, L & Fossey, JS 2018, 'Palladium and Platinum 2,4-cis-amino Azetidine and Related Complexes', Frontiers in Chemistry, vol. 6, 211. https://doi.org/10.3389/fchem.2018.00211

Zhao, Y, Van Nguyen, H, Male, L, Craven, P, Buckley, BR & Fossey, JS 2018, 'Phosphino-Triazole Ligands for Palladium-Catalyzed Cross-Coupling', Organometallics, vol. 37, no. 22, pp. 4224-4241. https://doi.org/10.1021/acs.organomet.8b00539

Yoshizawa, A, Feula, A, Male, L, Leach, AG & Fossey, JS 2018, 'Rigid and concave, 2,4-cis-substituted azetidine derivatives: A platform for asymmetric catalysis', Scientific Reports, vol. 8, no. 1, 6541. https://doi.org/10.1038/s41598-018-24784-3

Jin, JH, Li, XY, Luo, X, Fossey, JS & Deng, WP 2017, 'Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4 + 2] Cycloadditions Catalyzed by Amidine Derivatives', Journal of Organic Chemistry, vol. 82, no. 10, pp. 5424-5432. https://doi.org/10.1021/acs.joc.7b00367

Other contribution

Fossey, J 2020, Azetidines kill Mycobacterium tuberculosis without detectable resistance by blocking mycolate assembly.. https://doi.org/10.1101/2020.09.03.281170

Review article

Milton, JP & Fossey, JS 2021, 'Azetidines and their applications in asymmetric catalysis', Tetrahedron, vol. 77, 131767. https://doi.org/10.1016/j.tet.2020.131767

View all publications in research portal

Culture and collections

Schools, institutes and departments

Services and facilities