Dr Dhanak Gupta

School of Dentistry
Research Fellow

Contact details

Telephone
+44 (0) 121 466 5527
Email
d.gupta@bham.ac.uk

Dhanak Gupta is a Research Fellow in School of Dentistry. She is working on Ultrasurge project funded by EPSRC between Universities of Birmingham, Glasgow, Southampton, Edinburgh and Leeds. Her other research interests are bone cell biology, hard tissue regeneration and biomaterials designing.

Qualifications

PhD in Human Development, University of Nottingham, UK 2017

MSc in Medical Genetics, Newcastle University, UK, 2010

B.Tech in Industrial Biotechnology, Shri Mata Vaishno Devi University, India, 2009

Biography

Dhanak obtained her engineering degree in 2009 then went on to do an MSc degree in Medical genetics from Newcastle University in the UK. Then she joined as Junior Research Fellow to work on population genetics at University of Jammu in India. After obtaining a scholarship, she completed her PhD focusing on biomaterials and stem cells for bone regeneration in osteoporotic patients. She has worked in industry for some time and then did her post doc in the University of Sheffield at Prof. Gwendolen Reilly’s lab on a British Council Newton Fund project focusing on using fucoidan (derived from brown seaweed) as a bone regenerative and anti-cancer drug.

In March 2019, she joined as a Research Fellow in School of Dentistry and works on the Ultrasurge project funded by EPSRC between Universities of Birmingham, Glasgow, Southampton, Edinburgh and Leeds. This is a five-year project and involves development of a novel bone cutting device enabled by ultrasound. https://www.gla.ac.uk/research/az/ultrasurge/

Research

Multidisciplinary research in medical devices

  • Ultrasound and its effect on cells
  • Biomaterials for hard tissue regeneration
  • Osteoporosis management
  • Bone cell biology
  • Osteosarcoma treatment
  • Skills: Advanced microscopy techniques, material characterisations, molecular biology and tissue culture

Other activities

Associate member of Royal Society of Chemistry

Member IADR

Member European Society of Biomechanics

Publications

Gupta, D., Silva, M., Radziun, K., Martinez, D. C., Hill, C. J., Marshall, J., ... & Reilly, G. C. (2020). Fucoidan Inhibition of Osteosarcoma Cells Is Species and Molecular Weight Dependent. Marine Drugs, 18(2), 104.

Gupta, D., Kocot, M., Tryba, A. M., Serafim, A., Stancu, I. C., Jaegermann, Z., ... & Douglas, T. E. (2020). Novel naturally derived whey protein isolate and aragonite biocomposite hydrogels have potential for bone regeneration. Materials & Design, 188, 108408.

Gupta, D., Hossain, K. M. Z., Ahmed, I., Sottile, V., & Grant, D. M. (2018). Flame-Spheroidized Phosphate-Based Glass Particles with Improved Characteristics for Applications in Mesenchymal Stem Cell Culture Therapy and Tissue Engineering. Acs Applied Materials & Interfaces, 10(31), 25972-25982.

Felfel, R. M., Gupta, D., Zabidi, A. Z., Prosser, A., Scotchford, C. A., Sottile, V., & Grant, D. M. (2018). Performance of multiphase scaffolds for bone repair based on two-photon polymerized poly (d, l-lactide-co-ɛ-caprolactone), recombinamers hydrogel and nano-HA. Materials & Design, 160, 455-467.

Gupta, D., Grant, D. M., Zakir Hossain, K. M., Ahmed, I., & Sottile, V. (2018). Role of geometrical cues in bone marrow-derived mesenchymal stem cell survival, growth and osteogenic differentiation. Journal Of Biomaterials Applications, 32(7), 906-919.