Recent publications
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Kennedy, BC, Dean, I & Withers, DR 2023, 'Migration of stem-like CD8 T cells between tissue microenvironments underpins successful anti-tumour immune responses', Discovery Immunology, vol. 2, no. 1, kyad004. https://doi.org/10.1093/discim/kyad004
Molostvov, G, Gachechiladze, M, Shaaban, AM, Hayward, S, Dean, I, Dias, IHK, Badr, N, Danial, I, Mohammed, F, Novitskaya, V, Paniushkina, L, Speirs, V, Hanby, A, Nazarenko, I, Withers, DR, van Laere, S, Long, HM & Berditchevski, F 2023, 'Tspan6 stimulates the chemoattractive potential of breast cancer cells for B cells in an EV- and LXR-dependent manner', Cell Reports, vol. 42, no. 3, 112207. https://doi.org/10.1016/j.celrep.2023.112207
Li, Z, Tuong, ZK, Dean, I, Willis, C, Gaspal, F, Fiancette, R, Idris, S, Kennedy, B, Ferdinand, JR, Peñalver, A, Cabantous, M, Murtuza Baker, S, Fry, JW, Carlesso, G, Hammond, SA, Dovedi, SJ, Hepworth, MR, Clatworthy, MR & Withers, DR 2022, 'In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue', Journal of Experimental Medicine, vol. 219, no. 6, e20210749. https://doi.org/10.1084/jem.20210749, https://doi.org/10.1084/jem.20210749
Drummond, RA, Desai, JV, Ricotta, EE, Swamydas, M, Deming, C, Conlan, S, Quinones, M, Matei-Rascu, V, Sherif, L, Lecky, D, Lee, C-CR, Green, NM, Collins, N, Zelazny, AM, Prevots, DR, Bending, D, Withers, D, Belkaid, Y, Segre, JA & Lionakis, MS 2022, 'Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria', Cell Host & Microbe, vol. 30, no. 7, pp. 1020-1033.e6. https://doi.org/10.1016/j.chom.2022.04.013
Roberts, LB, Schnoeller, C, Berkachy, R, Darby, M, Pillaye, J, Oudhoff, MJ, Parmar, N, Mackowiak, C, Sedda, D, Quesniaux, V, Ryffel, B, Vaux, R, Gounaris, K, Berrard, S, Withers, DR, Horsnell, WGC & Selkirk, ME 2021, 'Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths', Science Immunology, vol. 6, no. 57, eabd0359. https://doi.org/10.1126/sciimmunol.abd0359
Bevington, S, Fiancette, R, Gajdasik, D, Keane, P, Soley, J, Willis, C, Coleman, D, Withers, D & Cockerill, P 2021, 'Stable epigenetic programming of effector and central memory CD4 T cells occurs within 7 days of antigen exposure in vivo', Frontiers in immunology, vol. 12, 642807. https://doi.org/10.3389/fimmu.2021.642807
Quraishi, MN, Acharjee, A, Beggs, AD, Horniblow, R, Tselepis, C, Gkoutos, G, Ghosh, S, Rossiter, A, Loman, N, van Schaik, W, Withers, D, Walters, JRF, Hirschfield, GM & Iqbal, TH 2020, 'A pilot integrative analysis of colonic gene expression, gut microbiota, and immune infiltration in primary sclerosing cholangitis-inflammatory bowel disease: association of disease with bile acid pathways', Journal of Crohn's & Colitis, vol. 14, no. 7, pp. 935-947. https://doi.org/10.1093/ecco-jcc/jjaa021
Bevington, SL, Keane, P, Soley, JK, Tauch, S, Gajdasik, DW, Fiancette, R, Matei-Rascu, V, Willis, CM, Withers, DR & Cockerill, PN 2020, 'IL-2/IL-7-inducible factors pioneer the path to T cell differentiation in advance of lineage-defining factors', The EMBO journal, vol. 39, no. 22, e105220. https://doi.org/10.15252/embj.2020105220
Perez-Toledo, M, Beristain Covarrubias, N, Channell, W, Hitchcock, J, Jones, C, Coughlan, R, Bobat, S, Jones, N, Nakamura, K, Ross, E, Rossiter, A, Rooke, J, Garcia-Gimenez, A, Jossi, S, Persaud, R, Marcial-Juarez, E, Flores-Langarica, A, Henderson, I, Withers, D, Watson, S & Cunningham, A 2020, 'Mice deficient in T-bet form inducible NO synthase–positive granulomas that fail to constrain salmonella', Journal of Immunology, vol. 205, no. 3, pp. 708-719. https://doi.org/10.4049/jimmunol.2000089
Gajdasik, DW, Gaspal, F, Halford, EE, Fiancette, R, Dutton, EE, Willis, C, Rückert, T, Romagnani, C, Gerard, A, Bevington, SL, MacDonald, AS, Botto, M, Vyse, T & Withers, DR 2020, 'Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues', Nature Communications, vol. 11, no. 1, 3421. https://doi.org/10.1038/s41467-020-17293-3
Melo-Gonzalez, F, Kammoun, H, Evren, E, Dutton, EE, Papadopoulou, M, Bradford, BM, Tanes, C, Fardus-Reid, F, Swann, JR, Bittinger, K, Mabbott, NA, Vallance, BA, Willinger, T, Withers, DR & Hepworth, MR 2019, 'Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria', The Journal of Experimental Medicine, vol. 216, no. 4, pp. 728-742. https://doi.org/10.1084/jem.20180871
Dutton, EE, Gajdasik, DW, Willis, C, Fiancette, R, Bishop, EL, Camelo, A, Sleeman, MA, Coccia, M, Didierlaurent, AM, Tomura, M, Pilataxi, F, Morehouse, CA, Carlesso, G & Withers, DR 2019, 'Peripheral lymph nodes contain migratory and resident innate lymphoid cell populations', Science Immunology, vol. 4, no. 35, eaau8082. https://doi.org/10.1126/sciimmunol.aau8082
Chu, C, Moriyama, S, Li, Z, Zhou, L, Flamar, A-L, Klose, CSN, Moeller, JB, Putzel, GG, Withers, DR, Sonnenberg, GF & Artis, D 2018, 'Anti-microbial Functions of group 3 innate lymphoid cells in gut-associated lymphoid tissues are regulated by G-protein-coupled receptor 183', Cell Reports, vol. 23, no. 13, pp. 3750-3758. https://doi.org/10.1016/j.celrep.2018.05.099
Flores-Langarica, A, Müller Luda, K, Persson, EK, Cook, CN, Bobat, S, Marshall, JL, Dahlgren, MW, Hägerbrand, K, Toellner, KM, Goodall, MD, Withers, D, Henderson, IR, Johansson Lindbom, B, Cunningham, A & Agace, WW 2018, 'CD103+CD11b+ mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin', Mucosal immunology, vol. 11, no. 3, pp. 681-692. https://doi.org/10.1038/mi.2017.105
Jones, R, Cosway, E, Willis, C, White, A, Jenkinson, W, Fehling, HJ, Anderson, G & Withers, D 2018, 'Dynamic changes in intrathymic ILC populations during murine neonatal development', European Journal of Immunology, vol. 48, no. 9, pp. 1481-1491. https://doi.org/10.1002/eji.201847511
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