Professor Adrian Heagerty BSc, MBBS, MD, FRCP

Professor Adrian Heagerty

Institute of Inflammation and Ageing
Honorary Professor of Dermatology

Contact details

Telephone
+44 (0)121 424 4563
Email
a.h.m.heagerty@bham.ac.uk
Address
Institute of Inflammation and Ageing
Birmingham University Research Labs
Queen Elizabeth Hospital
Mindelsohn Way
Birmingham
B15 2WB

Professor Heagerty is a Consultant Dermatologist and Honorary Professor of Dermatology at the University of Birmingham. He has a particular interest in the rare group of genetic skin diseases known collectively as Epidermolysis Bullosa. He leads several active research groups exploring genotype-phenotype correlation, inflammation, microbiome, scarring and therapeutics. He is academic lead for dermatology at the University of Birmingham/West Midlands Deanery and heads the half-national Epidermolysis Bullosa service at University Hospitals Birmingham NHS Foundation Trust.

Qualifications

  • FRCP (1999)
  • MD, University of London (1990)
  • MBBS, University of London (Guy’s Hospital) (1978)
  • BSc, First Class Honours, Pharmacology, University of London (Guy’s Hospital) (1975)

Postgraduate supervision

  • Academic Lead for dermatology at University of Birmingham.
  • Currently supervising MD and MRes students.
  • Professor Heagerty would welcome interested students to contact him to discuss potential projects.
  • External PhD examiner.

Research

  • Immune-microbial interplay in EB wounds
  • Genotype-phenotype correlation in EB
  • Anti-scarring therapies
  • Single-cell transcriptomics
  • Gait studies in EB

Other activities

  • Lead for Adult Epidermolysis Bullosa Unit, University Hospitals Birmingham NHS Foundation Trust
  • Member (and past Chair, until 2019), DEBRA International Medical and Scientific Advisory Panel
  • Previous Treasurer, REMEDI (Medical Research and Rehabilitation Trust)
  • Advisor, Skcin, The Karen Clifford Skin Cancer Charity

Publications

Selected publications

Bardhan, A., Bruckner-Tuderman, L., Chapple, I.L.C., Fine, J.-D., Harper, N., Has, C., Magin, T.M., Marinokovich, M.P., Marshall, J.F., McGrath, J.A., Mellerio, J.E., Polson, R. & Heagerty, A.H. (2020). Epidermolysis bullosa. Nat Rev Dis Primers. 6(78).

Has, C. , Bauer, J.W., Bodemer, C., Bolling, M.C., Bruckner-Tuderman, L.,  Diem, A., Fine, J.-D., Heagerty, A., Hovnanian, A., Marinkovich, M.P., Martinez, A.E., McGrath, J.A., Moss, C., Murrell, D.F., Palisson, F., Schwieger-Briel, A., Sprecher, E., Tamai, K., Uitto, J., Woodley, D.T., Zambruno, G., & Mellerio, J.E. (2020). Consensus re-classification of inherited epidermolysis bullosa and other disorders with skin fragility. Br. J. Dermatol. 183(4), 614-627.

Ungureanu, S., Adni, T., Brown, T., Inston, N. & Heagerty, A. (2014). Successful renal transplant in a patient with non-Herlitz junctional epidermolysis bullosa. Clin. Exp. Dermatol. 39, 330–332.

Shipman, A. R., Liu, L., Lai-Cheong, J. E., McGrath, J. A. & Heagerty, A. (2014). Somatic forward (nonrevertant) mosaicism in recessive dystrophic epidermolysis bullosa. JAMA Dermatol. 150, 1025–1027.

Lane, E., Rugg, E., Navsaria, H., Leigh, I.M., Heagerty, A.H., Ishida-Yamamoto, A., & Eady, R.A. (1992). A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering. Nature 356, 244–246.

Heagerty, A. H. et al. (1987). Rapid prenatal diagnosis of epidermolysis bullosa letalis using GB3 monoclonal antibody. Br. J. Dermatol. 117, 271–275.

Heagerty, A. H., Kennedy, A. R., Leigh, I. M., Purkis, P. & Eady, R. A. (1986). Identification of an epidermal basement membrane defect in recessive forms of dystrophic epidermolysis bullosa by LH 7:2 monoclonal antibody: use in diagnosis. Br. J. Dermatol. 115, 125–131.

Heagerty, A. H. et al. (1986). GB3 monoclonal antibody for diagnosis of junctional epidermolysis bullosa. Lancet 1, 860.

Heagerty, A. H., Kennedy, A. R., Gunner, D. B. & Eady, R. A. (1986). Rapid prenatal diagnosis and exclusion of epidermolysis bullosa using novel antibody probes. J. Invest. Dermatol. 86, 603–605.