Dr Laurentiu Craciunas Doctor-Medic, MSc, MRCOG

Dr Laurentiu Craciunas

Institute of Metabolism and Systems Research
PhD student

Contact details

+ 44 (0)121 472 1377 Extension: 5822
Academic Unit, 3rd Floor
Birmingham Women’s Hospital Foundation Trust
Mindelsohn Way
B15 2TG
ESHRE 2021: Conventional and modern markers of endometrial receptivity
The transcriptomic profile of endometrial receptivity in recurrent miscarriage

Laurentiu is a gynaecologist and researcher with interest in fertility, early pregnancy and miscarriage. He is a member of the Royal College of Obstetricians and Gynaecologists and he has undertaken a Masters in Genomic Medicine prior to embarking on the current PhD programme, under the supervision of Professor Arri Coomarasamy, where Laurentiu is planning to develop a test for endometrial receptivity in collaboration with Tommy's National Centre for Miscarriage Research.

As part of his PhD, Laurentiu is the chief investigator for a multicentre cohort study based on endometrial biopsies obtained from women who suffered unexplained recurrent miscarriages. Various OMICS techniques are being applied to the endometrial samples to identify particular molecular signatures (transcriptomics and metabolomics) linked with higher order miscarriages and with suffering another miscarriage or live birth in the subsequent pregnancies.

Laurentiu has extensive experience in secondary research having undergone Cochrane training which led to the publication of multiple systematic reviews and meta-analyses in the field of human reproduction.

Find out more on Laurentiu's blog.


  • MRCOG 2019
  • MSc in Genomic Medicine, Newcastle University, 2018
  • PG Certificate in Clinical Research, Newcastle University, 2016
  • Doctor – Medic, “Iuliu Hatieganu” University of Medicine and Pharmacy, 2011

Other activities

In parallel with his clinical and academic activity, Laurentiu is the junior deputy for the European Society of Human Reproduction and Embryology’s (ESHRE) Special Interest Group on Early Pregnancy and Implantation. He is also a member of the editorial board for Focus on Reproduction, ESHRE’s online magazine with news on human reproduction. Laurentiu is active in ESHRE’s Communications Committee and he is one of the founders of ESHRE’s journal club with monthly editions on Twitter under the hashtag #ESHREjc.


Craciunas L, Gallos I, Chu J, Bourne T, Quenby Q, Brosens JJ, Coomarasamy A. Conventional and modern markers of endometrial receptivity: a systematic review and meta-analysis. Hum Reprod Update 2019; 25: 202-223.

Akhtar MA, Sajjad Y, Brown J, Agrawal R, Craciunas L. Thyroxine replacement for subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism. Cochrane Database Syst Rev 2019; 6: CD011009

Craciunas L, Tsampras N, Raine-Fenning N, Coomarasamy A. Intrauterine administration of human chorionic gonadotropin (hCG) for subfertile women undergoing assisted reproduction. Cochrane Database Syst Rev 2018; 10: CD011537 

Craciunas L, Tsampras N. Bed rest following embryo transfer might negatively affect the outcome of IVF/ICSI: a systematic review and meta-analysis. Hum Fertil (Camb) 2016; 17: 1-7.

Craciunas L, Roberts SA, Yates AP, Smith A, Fitzgerald C, Pemberton PW. Modification of the Beckman-Coulter second-generation enzyme-linked immunosorbent assay protocol improves the reliability of serum antimullerian hormone measurement. Fertil Steril 2015; 103: 554-9.

Craciunas L, Stirbu L, Tsampras N. The use of a peritoneal gas drain following gynecological laparoscopy: a systematic review. Eur J Obstet Gynecol Reprod Biol 2014; 179: 224-8.

Craciunas L, Tsampras N. A literature review of the current evidence for routine antibiotic prophylaxis after cervical tissue excisions. J Obstet Gynaecol 2014; 34: 700-5.

Craciunas L, Tsampras N, Fitzgerald C. Cervical mucus removal prior to embryo transfer in women undergoing IVF/ICSI: a systematic review and meta-analysis of randomised controlled trials. Fertil Steril 2014; 101: 1302-7.

Craciunas L, Sajid MS, Ahmed AS. Chewing gum in preventing postoperative ileus in women undergoing caesarean section: A systematic review and meta-analysis of randomised controlled trials. BJOG 2014; 121: 793-9.

Craciunas L, Sajid MS, Howell R. Carbon dioxide versus normal saline as distension medium for diagnostic hysteroscopy: a systematic review and meta-analysis of randomised controlled trials. Fertil Steril 2013; 100: 1709-14.

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