Recent publications
Article
Southam, AD, Haglington, LD, Najdekr, L, Jankevics, A, Weber, RJM & Dunn, WB 2020, 'Assessment of human plasma and urine sample preparation for reproducible and high-throughput UHPLC-MS clinical metabolic phenotyping', The Analyst, vol. 145, no. 20, pp. 6511-6523. https://doi.org/10.1039/D0AN01319F
Fultang, L, Booth, S, Yogev, O, Costa, BMD, Tubb, V, Panetti, S, Stavrou, V, Scarpa, U, Jankevics, A, Lloyd, G, Southam, AD, Lee, SP, Dunn, W, Chesler, L, Mussai, FJ & Santo, CD 2020, 'Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity', Blood. https://doi.org/10.1182/blood.2019004500
Drury, N, Bi, R, Woolley, R, Stickley, J, Morris, KP, Montgomerie, J, Doorn, CV, Dunn, W, Madhani, M, Ives, N, Kirchhof, P & Jones, T 2020, 'The Bilateral Remote Ischaemic Conditioning in Children (BRICC) trial: protocol for a two-centre, double-blind, randomised controlled trial in young children undergoing cardiac surgery', BMJ open, vol. 10, no. 10, :e042176. https://doi.org/10.1136/bmjopen-2020-042176
Thompson, JW, Adams, KJ, Adamski, J, Asad, Y, Borts, D, Bowden, JA, Byram, G, Dang, V, Dunn, W, Fernandez, F, Fiehn, O, Gaul, DA, Hühmer, AFR, Kalli, A, Koal, T, Koeniger, S, Mandal, R, Meier, F, Fuad J., N, O'Neil, D, Pal, A, Patti, GJ, Pham-Tuan, H, Prehn, C, Raynaud, FI, Shen, T, Southam, A, St. John-Williams, L, Sulek, K, Vasilopoulou, CG, Viant, M, Winder, C, Wishart, D, Zhang, L, Zheng, J & Moseley, MA 2019, 'International ring trial of a high resolution targeted metabolomics and lipidomics platform for serum and plasma analysis', Analytical Chemistry, vol. 91, no. 22, 9b02908, pp. 14407-14416. https://doi.org/10.1021/acs.analchem.9b02908
Palmer, E, Cooper, H & Dunn, W 2019, 'Investigation of the 12-month stability and detectable metabolomes of dried blood and urine spots applying untargeted UHPLC-MS metabolomic assays', Analytical Chemistry, vol. 91, no. 22, pp. 14306−14313. https://doi.org/10.1021/acs.analchem.9b02577
D’Elia, R, Goodchild, S, Winder, CL, Southam, A, Weber, R, Stahl, F, Docx, C, Patel, V, Green, AC, Viant, M, Lukaszewski, R & Dunn, W 2019, 'Multiple metabolic pathways are predictive of ricin intoxication in a rat model', Metabolomics, vol. 15, no. 7, 102. https://doi.org/10.1007/s11306-019-1547-9
Sostare, J, Di Guida, R, Kirwan, J, Chalal, K, Palmer, E, Dunn, WB & Viant, MR 2018, 'Comparison of modified Matyash method to conventional solvent systems for polar metabolite and lipid extractions', Analytica Chimica Acta. https://doi.org/10.1016/j.aca.2018.03.019
Nash, W & Dunn, W 2018, 'From mass to metabolite in human untargeted metabolomics: recent advances in annotation of metabolites applying liquid chromatography-mass spectrometry data', Trends in Analytical Chemistry. https://doi.org/10.1016/j.trac.2018.11.022
Broadhurst, D, Goodacre, R, Reinke, SN, Kuligowski, J, Wilson, ID, Lewis, MR & Dunn, WB 2018, 'Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies', Metabolomics, vol. 14, no. 6, 72. https://doi.org/10.1007/s11306-018-1367-3
Dunn, W, Hulme, C, Stevens, A, Heazell, AEP, Begley, P, Hollywood, K, Westwood, M & Myers, J 2018, 'Identification of the functional pathways altered by placental cell exposure to high glucose: lessons from the transcript and metabolite interactome', Scientific Reports, vol. 8, 5270. https://doi.org/10.1038/s41598-018-22535-y
Lyall, M, Cartier, J, Thomson, JP, Cameron, K, Meseguer-Ripolles, J, O'Duibhir, E, Szkolnicka, D, Villarin, BL, Wang, Y, Rodriguez Blanco, G, Dunn, W, Meehan, RR, Hay, DC & Drake, AJ 2018, 'Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells', Philosophical Transactions of the Royal Society of London Series B, vol. 373, no. 1750, 20170362. https://doi.org/10.1098/rstb.2017.0362
Chortis, V, Taylor, A, Doig, C, Walsh, M, Meimaridou, E, Jenkinson, C, Rodriguez Blanco, G, Ronchi, C, Jaffri, A, Metherell, LA, Hebenstreit, D, Dunn, W, Arlt, W & Foster, P 2018, 'Nicotinamide nucleotide transhydrogenase as a novel treatment target in adrenocortical carcinoma', Endocrinology, vol. 159, no. 8, pp. 2836–2849. https://doi.org/10.1210/en.2018-00014
O'Reilly, M, Kempegowda, P, Walsh, M, Taylor, A, Manolopoulos, K, Allwood, W, Semple, R, Hebenstreit, D, Dunn, W, Tomlinson, J & Arlt, W 2017, 'AKR1C3-mediated adipose androgen generation drives lipotoxicity in polycystic ovary syndrome', Endocrine Abstracts. https://doi.org/10.1530/endoabs.49.oc3.3
O'reilly, M, Kempegowda, P, Walsh, M, Taylor, A, Manolopoulos, K, Allwood, JW, Semple, RK, Hebenstreit, D, Dunn, W, Tomlinson, J & Arlt, W 2017, 'AKR1C3-mediated adipose androgen generation drives lipotoxicity in women with polycystic ovary syndrome', Journal of Clinical Endocrinology and Metabolism, vol. 102, no. 9, pp. 3327–3339. https://doi.org/10.1210/jc.2017-00947
Comment/debate
Sostare, E, Di Guida, R, Kirwan, J, Chalal, K, Palmer, E, Dunn, WB & Viant, MR 2019, 'Erratum for “Comparison of modified Matyash method to conventional solvent systems for polar metabolite and lipid extractions” (Anal. Chim. Acta 1037 (2018), (301–315), (S0003267018303982), (10.1016/j.aca.2018.03.019))', Analytica Chimica Acta, vol. 1091. https://doi.org/10.1016/j.aca.2019.09.069
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