Dr Abd A Tahrani MD, MMedSci, CCT (Endocrinology and Diabetes), PhD, SCOPE (National Fellow), FRCP (London)

Dr Abd A Tahrani

Institute of Metabolism and Systems Research
NIHR Clinician Scientist at the University of Birmingham
Honorary Consultant in Obesity, Diabetes and Endocrinology at University Hospitals Birmingham NHS Foundation Trust.
Lead for Weight Management Research and Diabetic Neuropathy Services at Birmingham Heartlands Hospital

Contact details

Address
Office 12, 4th floor
Institute of Translational Medicine
Heritage Building
Mindelsohn Way, Edgbaston
Birmingham
B15 2TH

Abd Tahrani is a National Institute for Health Research (NIHR) Clinician Scientist at the University of Birmingham (UOB), and a Honorary Consultant Endocrinologist and Bariatric Physician at the University Hospitals Birmingham NHS Foundation Trust. Dr Tahrani is also the lead for weight management research and diabetic neuropathy services at Birmingham Heartlands Hospital and the lead for translation research in the Centre of Endocrinology, Diabetes and Metabolism and the communication co-lead at the Institute of Metabolism and Systems Research. 

He leads a multi-disciplinary research group that include scientists, clinicians and allied health-care professionals. The aims of this research group are to:

  1. examine the impact of sleep-related disorders (including obstructive apnoea) on metabolic health, diabetes and obesity
  2. improve our understanding of the pathogenesis of diabetes-related microvascular complications (peripheral neuropathy, autonomic neuropathy, nephropathy, retinopathy) and to identify new treatment targets and effective screening strategies
  3. improve our understanding of the pathogenesis of foot ulceration in diabetes and develop new treatments
  4. explore the pharmacological and non-pharmacological options to treat and manage patients with obesity (including the long-term outcomes of bariatric surgery)
  5. develop new treatments for type 2 diabetes

Dr. Tahrani has published over 125 peer reviewed articles and book chapters and in excess of 150 abstracts. He is regularly invited to speak in many of the leading national and international conferences in USA, Europe and Asia.

Dr. Tahrani has won several national and international awards including SCOPE National Fellow from the World Obesity Federation in 2014, The Diabetes UK best primary care poster award 2014, NIHR Clinician Scientist award in 2013, the American Academy of Sleep Medicine Sleep Disordered Breathing investigator of the year award in 2013, The Sanofi Aventis Clinical Excellence Award in 2009, the Society for endocrinology presentations award 2009, and a NIHR personal research training fellowship in 2008 in addition to several regional and local awards. He was also nominated to the Nick Hales young investigator award by Diabetes UK and he was recently elected as a member of Neurodiab (The diabetic neuropathy group of the EASD).

He previously served on the clinical committee of The Society for Endocrinology and is currently the diabetes and metabolism section editor for BMC Endocrine disorders and an editorial advisor to BMC Obesity. He serves on the editorial boards of several journals and was the editorial consultant for the type 1 diabetes module of the American College of Physicians.

Dr Tahrani is a regular reviewer of grants submitted to several NIHR streams and the Hong Kong research council amongst others and a regular peer reviewer to several leading journals in the fields of medicine, endocrinology, diabetes and obesity 

Dr. Tahrani is a member of the organising committee of the European Congress of Obesity 2019, a faculty member of the Neurodiab 2018 conference, a member of the NIHR RfPB and the NIHR Dissemination Centre. He also serves as an expert advisor to NICE. He was an examiner at the Royal College of Physicians in London.

Qualifications

  • SCOPE National Fellow in obesity, the World Obesity Federation, 2014
  • PhD in sleep, diabetes and microvascular complications, University of Birmingham, 2013
  • CCT in Diabetes and Endocrinology, 2012
  • MMedSci, Master of Medical Sciences, Keele University, 2008
  • MD in Medicine, University of Aleppo, Syria 1998

Biography

Abd Tahrani is a National Institute for Health Research (NIHR) Clinician Scientist at the University of Birmingham, an Honorary Consultant Endocrinologist at the University Hospitals of Birmingham NHS Foundation Trust, and the lead for weight management research and diabetic neuropathy services at Birmingham Heartlands Hospital. He is also the lead for translational research in the Centre of Endocrinology, Diabetes and Metabolism (CEDAM, Birmingham Health partners.

He obtained his PhD in 2013 from UoB and SCOPE National Fellowship in 2014 from the World Obesity Federation. His PhD examined the metabolic impacts of obstructive sleep apnoea in patients with Type 2 diabetes.  Abd’s research group has the following themes: the metabolic consequences of sleep-related disorders, obesity (comorbidities, health care delivery, management), diabetes-related microvascular complications (especially peripheral and autonomic neuropathy, epidemiology, pathogenesis and treatment), and the pharmacology of type 2 diabetes and obesity.

Abd has published over 125 peer reviewed articles, many in the leading journals in the field, six book chapters and more than 150 abstracts. He delivered more than 60 invited talks in the leading national and international conferences in Obesity, Diabetes, Endocrinology, and Sleep medicine. He has won several awards including the American Academy of Sleep Medicine Sleep Disordered Breathing investigator of the year award amongst others.

Abd is an elected member of Neurodiab, a trustee of the ASO (UK), a panel member of the NIHR RfPB, the NIHR Dissemination Centre, the Midlands ASO Network co-lead, a member of the program organising committee of ECO 2019, and an Expert advisor to the Medical Technology Advisory Committee of NICE.  

Postgraduate supervision

Currently has 7 PhD and 7 master students. The group is interested in students who are interested in the areas of obesity, sleep and diabetes meelitus.

Research

Research aims:

  • To examine the impact of sleep-related disorders (including obstructive apnoea) on metabolic health, diabetes and obesity
  • To improve our understanding of the pathogenesis of diabetes-related microvascular complications (peripheral neuropathy, autonomic neuropathy, nephropathy, retinopathy) and to identify new treatment targets and effective screening strategies.
  • To improve our understanding of the pathogenesis of foot ulceration in diabetes and develop new treatments
  • To explore the pharmacological and non-pharmacological options to treat and manage patients with obesity (including the long term outcomes of bariatric surgery)
  • To develop new treatments for type 2 diabetes

Research groups and centres

http://www.birmingham.ac.uk/research/activity/metabolism-systems/research/sleep-metabolism-obesity-and-diabetic-complication/index.aspx

Other activities

  • A member of the International Collaboration of Sleep Apnea Cardiovascular Trialists (INCOSACT)
  • A member of the Neurodiab
  • A member of the research committee of the British Sleep Society
  • Lead for Weight Management Research and Diabetic Neuropathy Services at Birmingham Heartlands Hospital
  • The Diabetes and Metabolism Section Editor for BMC Endocrine Disorders
  • An Editorial Advisor for BMC Obesity
  • An editorial board member of Review of Dibaetic Studies, clinical medicine case reports medical journal, the World Journal of Diabetes, Biomed Research International and the Journal of Translational Internal Medicine
  • Grant reviewer for national and international research funding organisations including the Hong Kong Medical Research Council, and National Institute for Health research (UK) including Health Technology Assessments (HTA), Research for Patient Benefit (RfPB), Efficacy and Mechanism Evaluation (EME) and Health Service Delivery evaluations
  • Regular peer reviewer to several leading journal including the Lancet, Lancet diabetes & endocrinology, Annals of internal Medicine, Journal of American College of Cardiology, BMJ, Canadian Medical Association Journal, Annals of Medicine, Thorax, Diabetes Care, Diabetologia, Diabetic Medicine, Clinical Endocrinology, British Journal of General Practice, BMC endocrine disorders, Thyroid, Endocrine Practice, Journal of the American Society of Nephrology, Drug and therapeutic bulletin, Ophthalmology, American Journal of Kidney Disease disorders, Diabetes Research and Clinical Practice, Cardiovascular Diabetologia, BMJ Open Diabetes Research, Journal of clinical sleep medicine,  Emirates Medical Journal, BMJ Open, Diabetes and Vascular Disease Research, PLOS One, PLOS Medicine, and Review of Diabetic Studies amongst others.
  • An expert advisor to the National Institute for Health Care Excellence (NICE) in England
  • A member of the NIHR RfPB West Midlands Panel
  • A member of NIHR Dissemination Centre
  • Previously a MRCP examiner
  • Previously an editorial consultant for the Type 1 diabetes module provided by the American College of Physicians
  • Previously served as a member of the Clinical committee of the Society of Endocrinology and the West Midlands postgraduate medicine board in the West Midlands Deanery.

Publications

Kahal H, Kyrou I, Uthman O, Brown A, Johnson S, Wall P, Metcalfe A, Tahrani A.A andRandeva H.S (2018) The association between obstructive sleep apnea and metabolic abnormalities in women with polycystic ovary syndrome: a systematic review and meta-analysis. Sleep. Jul 1;41(7).

Mistry P, Currie V, Super P, le Roux C.W, Tahrani A.A and Singhal R (2018) Changes in glycaemic control, blood pressure and lipids 5 years following laparoscopic adjustable gastric banding combined with medical care in patients with type 2 diabetes: a longitudinal analysis. Clin Obes. Jun;8(3):151-158.

Sahloul M, Karim A, Chohan K.S, Tahrani A.A, Mahawar K, Richardson M, Ludwig C, Daskalakis M, Singhal R and Roux-en-Y (2018) Gastric Bypass: Does the Direction of Staples Matter? Obes Surg. Apr 27.

Toulis KA, Bilezikian J.P, Thomas GN, Hanif W, Kotsa K, Thayakaran R, Keerthy D, Tahrani A.A and Nirantharakumar K (2018) Initiation of dapagliflozin and treatment-emergent fractures. Diabetes Obes Metab. Apr;20(4):1070-1074.

Karamat M.A, Dar S, Bellary S and Tahrani A.A (2018) Clinical and Cost Implications of Insulin Degludec in Patients with Type 1 Diabetes and Problematic Hypoglycemia: A Quality Improvement Project. Diabetes Ther. Apr;9(2):839-849.

Tahrani A.A, Bellary S and Barnett A.H (2018) Once-weekly GLP-1R agonists: moving the goal posts. Lancet Diabetes Endocrinol. Apr;6(4):260-261.

Tang T, Abbott S, le Roux C.W, Wilson V, Singhal R, Bellary S and Tahrani A.A (2018) Preoperative weight loss with glucagon-like peptide-1 receptor agonist treatment predicts greater weight loss achieved by the combination of medical weight management and bariatric surgery in patients with type 2 diabetes: A longitudinal analysis. Diabetes Obes Metab. Mar;20(3):745-748.

Fisher VL and Tahrani A.A (2017) Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives. Diabetes Metab Syndr Obes. Oct 6;10:419-434.

Altaf QA, Dodson P, Ali A, Raymond NT, Wharton H, Fellows H, Hampshire-Bancroft R, Shah M, Shepherd E, Miah J, Barnett AH and Tahrani A.A (2017) Obstructive Sleep Apnea and Retinopathy in Patients with Type 2 Diabetes. A Longitudinal Study. Am J Respir Crit Care Med. Oct 1;196(7):892-900.

Kahal H, Kyrou I, Tahrani A.A and Randeva HS (2017) Obstructive sleep apnoea and polycystic ovary syndrome: A comprehensive review of clinical interactions and underlying pathophysiology. Clin Endocrinol (Oxf). Oct;87(4):313-319.

For a full list of Dr A.A Tahrani's publications

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Expertise

Obesity, sleep apnoea, diabetes