Ms Lisa Vettore

Lisa Vettore

Institute of Metabolism and Systems Research
PhD student

Contact details

Email
lxv841@student.bham.ac.uk
Twitter
@LisaVettore
Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Lisa is a PhD student in Professor Tennant’s group. Her PhD project explores the role of proline metabolism in hypoxic cancers and the tumour-stroma metabolic interaction under low oxygen tensions.

Qualifications

MSc in Biomedical Sciences

Biography

Lisa graduated with a Msc in Biomedical Sciences (with honours) from the University of Padova (Italy) in 2017.

During her research training at the Veneto Institute of Oncology (IOV) in Italy she developed a strong interest in cancer metabolism. This interest led her to Belgium at the VIB-KU Leuven Center for Cancer Biology, where she worked on lipid metabolism in liver tumours. Then, she joined the Tennant lab to start her PhD at the University of Birmingham in 2018.

Research

Current PhD project

Investigating the role of proline metabolism in cancer and in the tumour microenvironment, under the supervision of Professor Daniel Tennant and Dr Christian Ludwig.

Research training

Exploring the role of lipid metabolism in liver cancer, under the supervision of Professor Sarah-Maria Fendt at the VIB-KU Leuven Center for Cancer Biology (Belgium) in 2018.

Masters degree project

Understanding the role of reactive oxygen species (ROS) in Diffuse large B-cell lymphoma with clinical applications, under the supervision of Professor Vincenzo Ciminale, Dr Francesco Ciccarese and Professor Ildikò Szabò at the Veneto Institute of Oncology (Italy) in 2017.

Research Group

https://www.tennantlab.uk/

Other activities

Student ambassador, University of Birmingham

Current memberships:

  • British Association for Cancer Research (BACR)
  • European Association for Cancer Research (EACR)
  • The New York Academy of Sciences (NYAS)

Publications

Recent publications

Article

Goncalves, J, Moog, S, Morin, A, Gentric, G, Muller, S, Morrell, A, Kluckova, K, Stewart, T, Andoniadou, C, Lussey-Lepoutre, C, Benit, P, Thakker, A, Vettore, L, Roberts, J, Rodriguez, R, Mechta-Grigoriou, F, Gimenez-Roqueplo, AP, Letouze, E, Tennant, D & Favier, J 2021, 'Loss of SDHB promotes dysregulated iron homeostasis, oxidative stress, and sensitivity to ascorbate', Cancer Research. https://doi.org/10.1158/0008-5472.CAN-20-2936

Vettore, LA, Westbrook, RL & Tennant, DA 2021, 'Proline metabolism and redox; maintaining a balance in health and disease', Amino Acids. https://doi.org/10.1007/s00726-021-03051-2

Vettore, L, Westbrook, RL & Tennant, DA 2020, 'New aspects of amino acid metabolism in cancer', British Journal of Cancer. https://doi.org/10.1038/s41416-019-0620-5

Kluckova, K, Thakker, A, Vettore, L, Escribano Gonzales, C, Hindshaw, R, Tearle, J, Goncalves, J, Kaul, B, Lavery, G, Favier, J & Tennant, D 2020, 'Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function', FASEB Journal, vol. 34, no. 1, pp. 303-315. https://doi.org/10.1096/fj.201901456R