Dr Carolyn Greig MSc PhD

Dr Carolyn Greig

Reader in Musculoskeletal Ageing and Health

Contact details

Address
School of Sport, Exercise and Rehabilitation Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Carolyn Greig is a translational scientist with research interests in the influence of use, disuse, age and disease on human skeletal muscle mass and function. She is particularly research active in the design and conduct of nutritional and physical activity interventions to maintain muscle mass and function in older healthy men and women and in frail patient groups. She also has an interest in human sedentariness and the development of interventions to reduce sitting time in older adults.  

Qualifications

  • BSc (Hons) University of Newcastle 1981
  • MSc University of London King’s College 1982
  • PhD Council for National Academic Awards 1988 (funded by the Sports Council of Great Britain)
  • Fellow of the Physiological Society 2017

Biography

Carolyn Greig graduated from Newcastle University (BSc Hons Physiology in 1981) and obtained an MSc in Human and Applied Physiology at King's College London (1982) and a Sports Council funded PhD from the Polytechnic of North London (1988). Following 2 years as a Lecturer in Exercise Physiology at St Mary's College of Higher Education, Strawberry Hill, she joined Prof Archie Young at the Royal Free Hospital School of Medicine as a Lecturer in Human and Applied Physiology in the Department of Geriatric Medicine. She created a Human Performance Laboratory and embarked on a programme of work based on development of methods of measurement and strategies to improve physical performance and functional ability in older people. During this time she trained the field workers who made the functional ability measurements included in the English National Fitness Survey, supervised MSc and PhD students and was the first non-clinical recipient of the Dhole Bursary from the British Geriatrics Society. 

From 1992-2000 she took a career break and moved to Edinburgh where she worked as a part-time visiting lecturer at Queen Margaret University before resuming her research career at Edinburgh University (2000-2012) as a Research Fellow before taking up her present position within SportexR and the prestigious MRC-ARUK Centre for Musculoskeletal Ageing Research at the University of Birmingham. Since 2000 Dr Greig has been a grant holder on >£2M of research funding and has authored over 85 peer-reviewed manuscripts, book chapters and review articles. In 2017 she was awarded Fellow of the Physiological Society.

Teaching

Carolyn contributes to a number of BSc and MSc modules within SportexR and the college of Medical and Dental Sciences. She co-directs and is a module lead for the MSc in Musculoskeletal Ageing which is run under the auspices of the MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research.

Postgraduate supervision

Carolyn has supervised/ co-supervised 5 doctoral students to completion and currently supervises a further 10 students as well as MSc/ MRes students. 

Research

Carolyn’s research is focussed on sarcopenia and frailty and in particular, optimising maintenance and improvement of muscle mass and function in older healthy men and women and in frail patient groups (including upper GI cancer, stroke). She has a keen interest in the following areas: skeletal muscle responsiveness to physical activity/ nutritional/ pharmacological interventions; molecular, biochemical and functional (imaging) biomarker discovery and evaluation; measurement of muscle protein synthesis; direct monitoring of physical activity; physiological and psychological responses to sedentariness and the development of interventions to reduce sitting time

CURRENT MAIN RESEARCH PROJECTS (majority supported via externally funded awards to support doctoral and postdoctoral researchers)

  1. Responsiveness of older muscle to resistance exercise training and manipulation of distribution of protein intake
  1. Understanding sedentary behaviour patterns/ acute effects of sitting time on physiological and psychological function in older adults
  1. Exercise and nutritional (Vitamin D3/ fish oil)  supplementation
  1. Influence of exercise and dietary restriction in obese older adults with knee OA
  1. Influence of lifelong exercise training preserve muscle metabolic health?
  1. Feasibility of pre-operative intervention to reduce sitting time in older adults awaiting knee/hip surgery
  1. Influence of nutritional supplementation after major trauma
  1. Impact of lifestyle modifications on function and health related quality of life in older individuals with sarcopenic obesity
  1. Direct objective physical activity monitoring as an outcome for studies of healthy ageing/ cancer cachexia 

Other activities

Within the University of Birmingham, Carolyn is theme lead for Exercise and Health within the School of Sport, Exercise and Rehabilitation Sciences and co-leads the interventions theme for the MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research. She is also a member of the University of Birmingham Clinical Trials Oversight Committee.

In addition, Carolyn is an active member of the UK Physiological Society and a co-opted member of the Society’s Meetings Committee. She is also a member of the Society for Sarcopenia, Cachexia and Wasting Disorders. She reviews for a number of journals and is a member of the Editorial Board of the Journal of Aging and Physical Activity. 

Publications

88 peer reviewed original articles, reviews and book chapters (H-index 22)

Welch C, Hassan-Smith ZK, Greig CA, Lord JM, Jackson TA. Acute Sarcopenia Secondary to Hospitalisation – An Emerging Condition Affecting Older Adults. Aging and Disease. 2017 8(6).http://dx.doi.org/10.14336/AD.2017.0315

Theodorakopoulos C, Jones J, Bannerman E, Greig CA. Effectiveness of nutritional and exercise interventions to improve body composition and muscle strength or function in sarcopenic obese older adults: A systematic review. Nutr Res. 2017 Jul;43:3-15. doi: 10.1016/j.nutres.2017.05.002. Epub 2017 May 11. Review

Antoniak AE, Greig CA. The effect of combined resistance exercise training and vitamin D3 supplementation on musculoskeletal health and function in older adults: a systematic review and meta-analysis. BMJ Open. 2017 Jul 20;7(7):e014619. doi: 10.1136/bmjopen-2016-014619

Willett M, Duda J, Gautrey C, Fenton S, Greig C, Rushton A. Effectiveness of behavioural change techniques in physiotherapy interventions to promote physical activity adherence in patients with hip and knee osteoarthritis: a systematic review protocol. BMJ Open. 2017 Jun 30;7(6):e015833. doi: 10.1136/bmjopen-2017-015833

Alrushud AS, Rushton AB, Kanavaki AM, Greig CA. Effect of physical activity and dietary restriction interventions on weight loss and the musculoskeletal function of overweight and obese older adults with knee osteoarthritis: a systematic review and mixed method data synthesis. BMJ Open. 2017 Jun 8;7(6):e014537. doi: 10.1136/bmjopen-2016-014537

Dall PM, Coulter EH, Fitzsimons CF, Skelton DA, Chastin S; Seniors USP Team. TAxonomy of Self-reported Sedentary behaviour Tools (TASST) framework for development, comparison and evaluation of self-report tools: content analysis and systematic review. BMJ Open. 2017 Apr 8;7(4):e013844. doi: 10.1136/bmjopen-2016-013844

Ebhardt HA, Degen S, Tadini V, Schilb A, Johns N, Greig CA, Fearon KC, Aebersold R, Jacobi C.
Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: A pilot study. J Cachexia Sarcopenia Muscle. 2017 Mar 15. doi: 10.1002/jcsm.12188. [Epub ahead of print]

Cardon-Thomas DK, Riviere T, Tieges Z, Greig CA. Dietary Protein in Older Adults: Adequate Daily Intake but Potential for Improved Distribution. Nutrients. 2017 Feb 23;9(3). pii: E184. doi: 10.3390/nu9030184

Da Boit M, Sibson R, Sivasubramaniam S, Meakin JR, Greig CA, Aspden RM, Thies F, Jeromson S, Hamilton DL, Speakman JR, Hambly C, Mangoni AA, Preston T, Gray SR. Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial. Am J Clin Nutr. 2017 Jan;105(1):151-158. doi: 10.3945/ajcn.116.140780

Jackson TA, Wilson D, Greig CA. Frailty and Ageing. In: The Ageing Immune System and Health. Eds: Bueno V, Lord JM, Jackson TA. Springer 2017. ISBN: 978-3-319-43363-9.

Thomas DK, Quinn MA, Saunders DH, Greig CA. Protein Supplementation Does Not Significantly Augment the Effects of Resistance Exercise Training in Older Adults: A Systematic Review. J Am Med Dir Assoc. 2016 Oct 1;17(10):959.e1-9. doi: 10.1016/j.jamda.2016.07.002. Review. PMID: 27670605

Brzeszczyńska J, Johns N, Schilb A, Degen S, Degen M, Langen R, Schols A, Glass DJ, Roubenoff R, Greig CA, Jacobi C, Fearon KC, Ross JA. Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly. Aging (Albany NY). 2016 Jul 23. [Epub ahead of print] PMID: 27454226

Saunders DH, Sanderson M, Hayes S, Kilrane M, Greig CA, Brazzelli M, Mead GE. Physical fitness training for stroke patients. Cochrane Database Syst Rev. 2016 Mar 24;3:CD003316. doi: 10.1002/14651858.CD003316.pub6. Review. PMID: 27010219

Greig CA, Jones DA. Muscle physiology and Contraction. Surgery (Oxford) 34 (2016) pp. 107-114 DOI: 10.1016/j.mpsur.2016.01.004

Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De Vito G, Donders G, Drey M, Greig C, Holmbäck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T. Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double-Blind, Placebo-Controlled Trial. J Am Med Dir Assoc. 2015 Jul 10. pii: S1525-8610(15)00388-6. doi: 10.1016/j.jamda.2015.05.021. [Epub ahead of print] PMID: 26170041

Stephens NA, Skipworth RJ, Gallagher IJ, Greig CA, Guttridge DC, Ross JA, Fearon KC.
Evaluating potential biomarkers of cachexia and survival in skeletal muscle of upper gastrointestinal cancer patients. J Cachexia Sarcopenia Muscle. 2015 Mar;6(1):53-61. doi: 10.1002/jcsm.12005. Epub 2015 Mar 31. PMID: 26136412

Milligan G, Greig C, Tipton M.  A literature review on the ageing workforce. May 2015, Energy Institute London ISBN 978 0 85293 736 5

Husi H, Skipworth RJ, Cronshaw A, Stephens NA, Wackerhage H, Greig C, Fearon KC, Ross JA.
Programmed cell death 6 interacting protein (PDCD6IP) and Rabenosyn-5 (ZFYVE20) are potential urinary biomarkers for upper gastrointestinal cancer. Proteomics Clin Appl. 2015 Jun;9(5-6):586-96. doi: 10.1002/prca.201400111. Epub 2015 May 8. PMID: 25644331

Duncan F, Lewis SJ, Greig CA, Dennis MS, Sharpe M, MacLullich AM, Mead GE.
Exploratory longitudinal cohort study of associations of fatigue after stroke. Stroke. 2015 Apr;46(4):1052-8. doi: 10.1161/STROKEAHA.114.008079. Epub 2015 Feb 12.
PMID: 25677595

Duncan F, Greig C, Lewis S, Dennis M, MacLullich A, Sharpe M, Mead G. Clinically significant fatigue after stroke: A longitudinal cohort study. J Psychosom Res. 2014 Nov;77(5):368-73. doi: 10.1016/j.jpsychores.2014.06.013. Epub 2014 Jul 5. PMID: 25439339

MacDonald AJ, Johns N, Stephens NA, Greig CA, Ross JA, Small AC, Husi H, Fearon KC, Preston T. Habitual myofibrillar protein synthesis is normal in patients with upper GI cancer cachexia. Clin Cancer Res. 2014 Nov 4. pii: clincanres.2004.2014. [Epub ahead of print] PMID: 25370466 [PubMed - as supplied by publisher]

Saunders DH, Greig CA, Mead GE. Physical activity and exercise after stroke: review of multiple meaningful benefits. Stroke. 2014 Dec;45(12):3742-7. doi: 10.1161/STROKEAHA.114.004311. Epub 2014 Nov 4. Review. No abstract available. PMID: 25370588

Tieges Z, Mead G, Allerhand M, Duncan F, van Wijck F, Fitzsimons C, Greig C, Chastin S.
Sedentary behaviour in the first year after stroke: a longitudinal cohort study with objective measures. Arch Phys Med Rehabil. 2014 Sep 11. pii: S0003-9993(14)01028-4. doi: 10.1016/j.apmr.2014.08.015. [Epub ahead of print] PMID: 25220942

Greig CA, Johns N, Gray C, MacDonald A, Stephens NA, Skipworth RJ, Fallon M, Wall L, Fox GM, Fearon KC. Phase I/II trial of formoterol fumarate combined with megestrol acetate in cachectic patients with advanced malignancy. Support Care Cancer. 2014 May;22(5):1269-75. doi: 10.1007/s00520-013-2081-3. Epub 2014 Jan 4.PMID: 24389826

Kilgour AH, Gallagher IJ, MacLullich AM, Andrew R, Gray CD, Hyde P, Wackerhage H, Husi H, Ross JA, Starr JM, Chapman KE, Fearon KC, Walker BR, Greig CA. Increased skeletal muscle 11βHSD1 mRNA is associated with lower muscle strength in ageing. PLoS One. 2013 Dec 31;8(12):e84057. doi: 10.1371/journal.pone.0084057. eCollection 2013. PMID: 24391882

Nicholson SL, Donaghy M, Johnston M, Sniehotta FF, van Wijck F, Johnston D, Greig C, McMurdo ME, Mead G. A qualitative theory guided analysis of stroke survivors' perceived barriers and facilitators to physical activity. Disabil Rehabil. 2013 Dec 31. [Epub ahead of print] PMID: 24377329

Husi H, Barr JB, Skipworth RJ, Stephens NA, Greig CA, Wackerhage H, Barron R, Fearon KC, Ross JA. The Human Urinary Proteome Fingerprint Database UPdb. Int J Proteomics. 2013;2013:760208. doi: 10.1155/2013/760208. Epub 2013 Oct 9. PMID: 24222850

Greig CA. Nutritional approaches to the management of sarcopenia. Nutrition Bulletin 2013 DOI: 10.1111/nbu.12046 (invited review)

Stewart VH, Saunders DH, Greig CA. Responsiveness of muscle size and strength to physical training in very elderly people: A systematic review. Scand J Med Sci Sports. 2013 Oct 24. doi: 10.1111/sms.12123. [Epub ahead of print] PMID: 24151875

Saunders DH, Sanderson M, Brazzelli M, Greig CA, Mead GE. Physical fitness training for stroke patients. Cochrane Database Syst Rev. 2013 Oct 21;10:CD003316. doi: 10.1002/14651858.CD003316.pub5. PMID: 24142492

Cooney GM, Dwan K, Greig CA, Lawlor DA, Rimer J, Waugh FR, McMurdo M, Mead GE.
Exercise for depression. Cochrane Database Syst Rev. 2013 Sep 12;9:CD004366. doi: 10.1002/14651858.CD004366.pub6. PMID:24026850

MacDonald AJ, Small AC, Greig CA, Husi H, Ross JA, Stephens NA, Fearon KC, Preston T.
A novel oral tracer procedure for measurement of habitual myofibrillar protein synthesis. Rapid Commun Mass Spectrom. 2013 Aug 15;27(15):1769-77. doi: 10.1002/rcm.6622.

Kutlubaev MA, Shenkin SD, Farrall AJ, Duncan FH, Lewis SJ, Greig CA, Dennis MS, Wardlaw JM, Maclullich AM, Mead GE. CT and Clinical Predictors of Fatigue at One Month after Stroke. Cerebrovasc Dis Extra. 2013 Mar 22;3(1):26-34. doi: 10.1159/000347113. eCollection 2013. PMID: 24052792

Saunders DH, Greig CA. Evidence for exercise and fitness training after stroke. In: Exercise and Fitness Training After Stroke, Eds: Mead G, van Wijck F. Churchill Livingstone Edinburgh 2013

Nicholson S, Sniehotta FF, van Wijck F, Greig CA, Johnston M, McMurdo ME, Dennis M, Mead GE. A systematic review of perceived barriers and motivators to physical activity after stroke. Int J Stroke. 2013 Jul;8(5):357-64. doi: 10.1111/j.1747-4949.2012.00880.x. Epub 2012 Sep 13.] PMID: 22974010

Johns N, Greig C, Fearon KC. Is tissue cross-talk important in cancer cachexia? Crit Rev Oncog. 2012;17(3):263-76. Review. PMID: 22831157

Brazzelli M, Saunders DH, Greig CA, Mead GE. Physical fitness training for patients with stroke: updated review. Stroke. 2012 Apr;43(4):e39-e40. Review

Rimer J, Dwan K, Lawlor DA, Greig CA, McMurdo M, Morley W, Mead GE. Exercise for depression. Cochrane Database Syst Rev. 2012 Jul 11;7:CD004366. doi: 10.1002/14651858.CD004366.pub5. Review

Stephens NA, Gray C, MacDonald AJ, Tan BH, Gallagher IJ, Skipworth RJE, Ross JA, Fearon KCH, Greig CA. Sexual dimorphism modulates the impact of cancer cachexia on lower limb muscle mass and function Clin Nutr. 2012 Aug;31(4):499-505. Doi 10.1016/j.clnu.2011.12.008. Epub 2012 Jan 31

Stephens NA. Gallager IJ, MacDonald A, Skipworth RJE, Husi H, Greig CA, Ross JA, Timmons JA, Fearon KCH. Suppression of skeletal muscle turnover in cancer cachexia: evidence from the transcriptome in sequential human muscle biopsies. Clin Cancer Res. 2012 May 15;18(10):2817-27. Epub 2012 Mar 27

Carroll SL, Greig CA, Lewis SJ, McMurdo MET, Sniehotta FF, Johnston M, Johnston DW, Scopes J, Mead GE. The use of pedometers in stroke survivors: are they feasible and how well do they detect steps? Arch Phys Med Rehabil. 2012 Mar;93(3):466-70

Duncan F, Kutlubaev M, Dennis M, Greig C, Mead,GE. Fatigue after stroke: a systematic review of associations with impaired physical fitness. Int J Stroke. 2012 Feb;7(2):157-62. doi: 10.1111/j.1747-4949.2011.00741.x. Review

Ferriolli E, Skipworth RJE, Hendry P, Scott A, , Stensteth J, Dahele M, Wall L, Greig C, Fallon
M, Strasser F, Preston T, Fearon KCH.  Physical activity monitoring: a responsive and meaningful patient-centred outcome for surgery, chemotherapy or radiotherapy? J Pain Symptom Manage. 2012 Jun;43(6):1025-35. doi: 10.1016/j.jpainsymman.2011.06.013. Epub 2012 Jan 24.

Chastin SFM, Ferriolli E, Stephens NA, Fearon KCH, Greig C. Relationship between sedentary behaviour, physical activity, muscle quality and body composition in healthy older adults. Age Ageing 2012 Jan;41(1):111-4

Brazzelli M, Saunders DH, Greig CA, Mead GE. Physical fitness training for stroke patients. Cochrane Database of SystematicReviews 2011, Issue 11. Art. No.: CD003316. DOI: 10.1002/14651858.CD003316.pub4

MacDonald A, Greig CA, Baracos V. The advantages and limitations of cross-sectional body composition analysis. Current opinion in supportive and palliative care 2011, 5: 342-349

Barreto PS, Greig CA, Ferrandez A-M. Detecting and categorising frailty status in older adults using a self-report screening instrument. Archives of Gerontology and Geriatrics. Arch. Gerontol. Geriatr. (2011), doi:10.1016/j.archger.2011.08.003

Greig CA, Gray C, Rankin D, Young A, Mann V, Noble B, Atherton PA.
Blunting of adaptive responses to resistance exercise training in women over 75 y. J Exp Gerontol. 2011 Nov; 46(11):884-90

Stephens NA, Skipworth RJE, MacDonald A, Greig CA, Ross JA, Fearon KCH.
Intramyocellular lipid droplets increase with progression of weight loss in cancer patients. J Cachex Sarcopenia Muscle. 2011 Jun;2(2):111-117. Epub 2011 May 31

Husi H, Stephens N, Cronshaw A, MacDonald A, Gallagher I, Greig C, Fearon KCH, Ross J.
Proteomic analysis of urinary upper gastrointestinal cancer markers. Proteomics Clin Appl. 2011 Jun;5(5-6):289-99. doi: 10.1002/prca.201000107. Epub 2011 Apr 28

Ratkevicius A, Joyson A, Selmer I, Dhanani T, Grierson C, Tommasi AM, DeVries A, Rauchhaus P, Crowther D, Alesci S, Yaworsky P, Gilbert F, Redpath TW, Brady J, Fearon KCH, Reid D, Greig CA, Wackerhage H. Serum concentrations of myostatin and myostatin-interacting proteins do not differ between young and sarcopenic, elderly men. J Gerontol A Biol Sci Med Sci. 2011 Mar 7

Lewis SJ, Barugh AJ, Greig CA,  Saunders DH, Fitzsimons C, Dinan-Young S, Young A, Mead
GE. Is Fatigue After Stroke Associated With Physical Deconditioning? A Cross-Sectional Study in Ambulatory Stroke Survivors. Arch Phys Med Rehabil. 2011 Feb;92 (2):295-8

Gray C, MacGillivray TJ, Eeley C, Stephens NA, Fearon KCH, Greig CA. Magnetic resonance imaging with k-means clustering objectively measures whole muscle volume compartments in sarcopenia/cancer cachexia. Clinical Nutrition 2011; 30: 106-111

Greig CA, Atherton PJ, Rennie MJ. Can an NSAID a day keep muscle wasting away? Clinical Perspective. J Physiol 587.24 (2009) pp 5799–5800

Jones DA, Greig CA. The control of muscle contraction, Surgery (2009), doi:10.1016/ j.mpsur.2009.10.017

Greig CA, Jones DA. Muscle physiology, Surgery (2009), doi:10.1016/ j.mpsur.2009.10.019

Saunders D, Greig C, Young A, Mead G. 2010 Physical Fitness Training for Patients with Stroke: An Updated Review.Stroke 2009, 41(3), pp. 160-161

MacGillivray T J, Ross E, Simpson AHRW, Greig CA. 3D Freehand Ultrasound for in vivo Determination of Human Skeletal MuscleVolume Ultrasound in Medicine and Biology. 2009, 35 (6): 928-935

Saunders D, Greig C, Young A, Mead G. Physical fitness training for stroke patients.Updated systematic review for the Cochrane Database of Systematic Reviews, Vol. Issue 4 2009

Mead GE, Morley W, Campbell P, Greig CA, McMurdo M, Lawlor DA.  Exercise for depression. Cochrane Database of Systematic Reviews 2008, Issue 4. Art. No.: CD004366. DOI: 10.1002/14651858.CD004366.pub3

Carin-Levy G, Greig CA, Lewis SJ, Stewart A, Young A, Mead GE. The effect of different body positions on anthropometric measurements and derived estimates of body composition. International Journal of Body Composition Research 2008; 6 (1): 17-20

Saunders DH, Greig CA, Young A, Mead GE. Association of activity limitations and lower-limb explosive extensor power in ambulatory people with stroke. Arch Phys Med Rehabil 2008; 89 (4): 677-683

Lynch J, Mead GE, Greig CA, Young A, Lewis S, Sharpe M. Development and evaluation of a case definition for fatigue after stroke. J Psychosom Res 2007; 63:539-544

Mead GE, Greig CA, Cunningham I, Lewis SJ, Dinan S, Saunders DH, Fitzsimons C, Young A. Stroke: a randomized trial of exercise or relaxation. J Am Geriatr Soc 2007; 55 (6): 892-899

Mead G, Lynch J, Greig C, Young A, Lewis S, Sharpe M. Evaluation of fatigue scales in stroke patients Stroke. 2007 Jul; 38 (7): 2090-5. Epub 2007 May 24

Fitzsimons, C.F, Simpson, AHRW, Young, A, Greig C. Oxygen uptake kinetics measured at the onset of comfortable self-paced walking in elderly women after hip fracture. Eur J Appl Physiol. 2007 Jun; 100 (3): 355-62. Epub 2007 Apr 12

Greig CA, Hameed M, Young A, Goldspink G, Noble B.  Skeletal muscle IGF-I isoform expression in healthy women after isometric exercise. Growth Horm IGF Res. 2006 Oct Dec;16(5-6):373-6

Carin-Levy G, Greig C, Lewis S, Hannan J, Young A, Mead G. Longitudinal changes in muscle strength and mass after stroke. Cerebrovasc Dis 2006;21:201-207

Fitzsimons C, Greig C, Saunders D, Lewis S, Shenkin S, Lavery C, Young A. Response to walking speed instructions: Implications for health promotion in old age. Journal of Physical Activity and Aging 2005, 13: 172-183

Saunders DH, Greig CA, Young A, Mead GE. Physical fitness training for stroke patients. Stroke 2004, 35: 2235

Saunders DH, Greig CA, Young A, Mead GE. Physical fitness training for stroke patients. (Cochrane Review). In: The Cochrane Library, Issue 1, 2004. Chichester UK: John Wiley & Sons, Ltd

Greig CA. The trainability of elderly people. Age and Ageing 2002, 31: 223-224. (Invited Editorial)

Malbut-Shennan KM, Greig C, Young A. Aerobic Exercise. In: Section on ‘Muscle’, section ed. A.Young, In: Oxford Textbook of  Geriatric Medicine 2nd Edition, eds. J.G. Evans, T.F. Williams, B.L. Beattie, J.-P. Michel, G.K. Wilcock, pp. 972-979.Oxford University Press, Oxford, 2000

Skelton DA, Young A, Greig CA. Muscle function of women aged 65-89 years meeting two sets of health criteria. Aging: Clinical and Experimental Research 1997, 9: 106-111

Skelton DA, Young A, Greig CA, Malbut KE. Effects of resistance training on strength, power, and selected functional abilities of women aged 75 and older. Journal of the American Geriatrics Society 1995, 43: 1081-1087

Skelton DA, Greig CA, Davies JM, Young A. Strength, power and related functional ability of healthy people aged 65-89 years. Age and Ageing 1994, 23: 371-377

Young A, Botella J, Greig CA, Skelton DA. Functional performance assessment in old age. In: Physical Activity Aging and Sports 111; Toward Healthy Aging – International Perspectives. Part 1, Physiological and  Biomedical Aspects. Eds. S. Harris, H. Suominen, P. Era, W.S. Harris, pp.149-159. Center for the Study of Aging; Albany, New York, 1994

Greig CA, Young A, Skelton DA, Pippet E, Butler FMM, Mahmud SM. Exercise studies with elderly volunteers. Age and Ageing 1994, 23 : 185-189

Greig CA, Butler FMM, Skelton DA, Mahmud SM, Young A. Treadmill walking may not reproduce the real-life situation. Journal of the American Geriatrics Society 1993, 41: 15-18

Greig CA, Botella J, Young A. The quadriceps strength of healthy elderly people remeasured after eight years. Muscle and Nerve 1993, 16: 6-10

Greig CA, Young A. Aerobic Exercise. In: Section on ‘Muscle’, section ed. A. Young. In: Oxford Textbook of Geriatric Medicine. Eds. J.G. Evans, T.F. Williams. Ch. 19.2, pp. 601-604. Oxford University Press, Oxford, 1992

Davies SW, Greig CA, Jordan SL, Grieve DW, Lipkin DP. Short-stepping gait in severe heart failure. British Heart Journal 1992, 55: 469-472

Ebrahim, S.B.J., Patel, N., Coats, M., Greig, C.A., Gilley, J., Bangham, C., Stacey, S. Prevalence and severity of morbidity amongst Gujurati Asian elders: a controlled comparison. Family Practice, 8: 57-62, 1991

Sargeant AJ, Greig C. Effect of fatigue on emg and force during maximal short-term exercise. In: Intenational Series on Biomechanics. Biomechanics X1B, 903-906. Eds. G. de Groot, A.P. Hollander, P.A. Huijing, G.J. van Ingen Schenau. Free University Press, Amsterdam, 1988

Sargeant AJ, Greig C. Maximum leg force and proportional utilisation during cycling. In: International Series on Biomechanics. Biomechanics X1B, 907-910. Eds. G. de Groot, A.P.Hollander, P.A. Huijing, G.J. van Ingen Schenau. Free University Press,              Amsterdam, 1988

Greig C, Finch KM, Jones DA, Cooper M, Sargeant AJ, Forte CA. The effect of oral supplementation with L-carnitine on maximum and submaximum exercise capacity. European Journal of Applied Physiology 1987, 56: 457-460

Davidson R, Greig CA, Husain A, Saunders KB. Within-breath changes of airway calibre in patients with airflow obstruction by continuous measurement of respiratory impedance. British Journal of Diseases of the Chest 1986, 80: 4, 335-352

Rutherford OM, Greig CA, Sargeant AJ, Jones DA. Strength-training and power output. Transference effects in the human quadriceps muscle. Journal of Sports Science 1986, 4: 101-107