Recent publications
Article
Cumberland, M, Euchner, J, Azad, A, Vo, NTN, Kirchhof, P, Holmes, A, Denning, C & Gehmlich, K 2024, 'Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model [version 1; peer review: 1 approved, 2 approved with reservations]', F1000Research, vol. 12, 1224. https://doi.org/10.12688/f1000research.139482.1
Sommerfeld, LC, Holmes, AP, Yu, TY, O'Shea, C, Kavanagh, DM, Pike, JM, Wright, T, Syeda, F, Aljehani, A, Kew, T, Cardoso, VR, Kabir, SN, Hepburn, C, Menon, PR, Broadway‐Stringer, S, O'Reilly, M, Witten, A, Fortmueller, L, Lutz, S, Kulle, A, Gkoutos, GV, Pavlovic, D, Arlt, W, Lavery, GG, Steeds, R, Gehmlich, K, Stoll, M, Kirchhof, P & Fabritz, L 2024, 'Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse', The Journal of Physiology. https://doi.org/10.1113/jp284597
Hall, C, Law, JP, Reyat, JS, Cumberland, MJ, Hang, S, Vo, NTN, Raniga, K, Weston, CJ, O’Shea, C, Townend, JN, Gehmlich, K, Ferro, CJ, Denning, C & Pavlovic, D 2023, 'Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype', Scientific Reports, vol. 13, no. 1, 12137. https://doi.org/10.1038/s41598-023-39369-y
Gehmlich, K & Krause, S 2023, 'How we name academic prizes matters', Nature Human Behaviour. https://doi.org/10.1038/s41562-023-01773-9
Broadway-Stringer, S, Jiang, H, Wadmore, K, Hooper, C, Douglas, G, Steeples, V, Azad, AJ, Singer, E, Reyat, JS, Galatik, F, Ehler, E, Bennett, P, Kalisch-Smith, JI, Sparrow, DB, Davies, B, Djinovic-Carugo, K, Gautel, M, Watkins, H & Gehmlich, K 2023, 'Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2', Cells, vol. 12, no. 5, 721. https://doi.org/10.3390/cells12050721
Patel, L, Roy, A, Mia B Alvor, A, Yuan, M, Baig, S, V Bunting, K, Hodson, J, Gehmlich, K, M Lord, J, Geberhiwot, T & Paul Steeds, R 2023, 'Phenoage and longitudinal changes on transthoracic echocardiography in Alström Syndrome: A disease of accelerated ageing?', GeroScience. https://doi.org/10.1007/s11357-023-00959-3
McColgan, G, Villarroel, M & Gehmlich, K 2023, 'Should young athletes be screened for cardiomyopathies to reduce the burden of sudden cardiac death in athletes?', Biophysical Reviews, vol. 15, no. 3, pp. 321-327. https://doi.org/10.1007/s12551-023-01085-2
Cumberland, M, Riebel, LL, Roy, A, O'Shea, C, Holmes, A, Denning, C, Kirchhof, P, Rodriguez, B & Gehmlich, K 2022, 'Basic Research Approaches to Evaluate Cardiac Arrhythmia in Heart Failure and Beyond', Frontiers in Physiology, vol. 13, 806366. https://doi.org/10.3389/fphys.2022.806366
O'Reilly, M, Sommerfeld, LC, O'Shea, C, Broadway-Stringer, S, Andaleeb, S, Reyat, JS, Kabir, SN, Stastny, D, Malinova, A, Delbue, D, Fortmueller, L, Gehmlich, K, Pavlovic, D, Skryabin, BV, Holmes, AP, Kirchhof, P & Fabritz, L 2022, 'Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide', EP Europace. https://doi.org/10.1093/europace/euac218
Hall, C, Gehmlich, K, Denning, C & Pavlovic, D 2021, 'Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease', Journal of the American Heart Association, vol. 10, no. 5, e019338. https://doi.org/10.1161/JAHA.120.019338
Jiang, H, Hooper, C, Kelly, M, Steeples, V, Simon, J, Beglov, J, Azad, A, Leinhos, L, Bennett, P, Ehler, E, Kalisch-Smith, J, Sparrow, D, Fischer, R, Heilig, R, Isackson, H, Ehsan, M, Patone, G, Huebner, N, Davies, B, Watkins, H & Gehmlich, K 2021, 'Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant', Basic research in cardiology, vol. 116, no. 1, 14, pp. 14. https://doi.org/10.1007/s00395-021-00853-z
Review article
Noureddine, M & Gehmlich, K 2023, 'Structural and signaling proteins in the Z-disk and their role in cardiomyopathies', Frontiers in Physiology, vol. 14, 1143858. https://doi.org/10.3389/fphys.2023.1143858
Patel, L, Worch, JC, Dove, AP & Gehmlich, K 2023, 'The Utilisation of Hydrogels for iPSC-Cardiomyocyte Research', International Journal of Molecular Sciences, vol. 24, no. 12, 9995. https://doi.org/10.3390/ijms24129995
Wadmore, K, Azad, A & Gehmlich, K 2021, 'The role of Z-disc proteins in myopathy and cardiomyopathy', International Journal of Molecular Sciences, vol. 22, no. 6, 3058, pp. 1-30. https://doi.org/10.3390/ijms22063058
Sontayananon, N, Redwood, C, Davies, B & Gehmlich, K 2020, 'Fluorescent PSC-derived cardiomyocyte reporter lines: generation approaches and their applications in cardiovascular medicine', Biology, vol. 9, no. 11, 402, pp. 1-24. https://doi.org/10.3390/biology9110402
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