Recent publications
Article
Elliot, TAE, Lecky, DAJ & Bending, D 2023, 'T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures', Essays in Biochemistry, vol. 2023, EBC20220247. https://doi.org/10.1042/EBC20220247
Whyte, CE, Singh, K, Burton, OT, Aloulou, M, Kouser, L, Veiga, RV, Dashwood, A, Okkenhaug, H, Benadda, S, Moudra, A, Bricard, O, Lienart, S, Bielefeld, P, Roca, CP, Naranjo-Galindo, FJ, Lombard-Vadnais, F, Junius, S, Bending, D, Hochepied, T, Halim, TYF, Schlenner, S, Lesage, S, Dooley, J & Liston, A 2022, 'Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits', The Journal of Experimental Medicine, vol. 219, no. 7, e20212391. https://doi.org/10.1084/jem.20212391
Sheriff, L & Bending, D 2022, 'Flow cytometric analysis of CD4+ T cell re-activation following anti-PD1 immunotherapy in a transgenic mouse model', STAR Protocols, vol. 3, no. 1, 101161. https://doi.org/10.1016/j.xpro.2022.101161
Drummond, RA, Desai, JV, Ricotta, EE, Swamydas, M, Deming, C, Conlan, S, Quinones, M, Matei-Rascu, V, Sherif, L, Lecky, D, Lee, C-CR, Green, NM, Collins, N, Zelazny, AM, Prevots, DR, Bending, D, Withers, D, Belkaid, Y, Segre, JA & Lionakis, MS 2022, 'Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria', Cell Host & Microbe, vol. 30, no. 7, pp. 1020-1033.e6. https://doi.org/10.1016/j.chom.2022.04.013
Elliot, T, Jennings, E, Lecky, D, Rouvray, S, MacKie, G, Scarfe, L, Sheriff, L, Ono, M, Maslowski, K & Bending, D 2022, 'Nur77-Tempo mice reveal T cell steady state antigen recognition', Discovery Immunology, vol. 1, no. 1, kyac009. https://doi.org/10.1093/discim/kyac009
Gudgeon, N, Munford, H, Bishop, EL, Hill, J, Fulton-Ward, T, Bending, D, Roberts, J, Tennant, DA & Dimeloe, S 2022, 'Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation', Cell Reports, vol. 40, no. 7, 111193. https://doi.org/10.1016/j.celrep.2022.111193
Elliot, T, Jennings, E, Lecky, D, Thawait, N, Flores-Langarica, A, Copland, A, Maslowski, K, Wraith, D & Bending, D 2021, 'Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength', Immunity, vol. 54, no. 11, pp. 2481-2496.e6. https://doi.org/10.1016/j.immuni.2021.08.020
Jennings, E, Lecky, D, Ono, M & Bending, D 2021, 'Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry', STAR Protocols, vol. 2, no. 1, 100284. https://doi.org/10.1016/j.xpro.2020.100284
Jennings, E, Elliot, T, Thawait, N, Kanabar, S, Yam-Puc, JC, Ono, M, Toellner, K-M, Wraith, DC, Anderson, G & Bending, D 2020, 'Nr4a1 and Nr4a3 reporter mice are differentially sensitive to T cell receptor signal strength and duration', Cell Reports, vol. 33, no. 5, 108328. https://doi.org/10.1016/j.celrep.2020.108328, https://doi.org/10.1016/j.celrep.2020.108328
Bending, D, Prieto Martin, P, Paduraru, A, Ducker, C, Marzaganov, E, Laviron, M, Kitano, S, Miyachi, H, Crompton, T & Ono, M 2018, 'A Timer for analyzing temporally dynamic changes in transcription during differentiation in vivo', Journal of Cell Biology, vol. 217, no. 8, pp. 2931-2950. https://doi.org/10.1083/jcb.201711048
Bending, D, Paduraru, A, Ducker, C, Prieto Martin, P, Crompton, T & Ono, M 2018, 'A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme', The EMBO journal, vol. 37, no. 16, e99013. https://doi.org/10.15252/embj.201899013
Rosser, E, Lom, H, Bending, D, Duurland, C, Bajaj-Elliott, M & Wedderburn, LR 2018, 'Brief report: Innate lymphoid cells and T-cells contribute to the IL-17A signature detected in the synovial fluid of patients with Juvenile Idiopathic Arthritis', Arthritis and Rheumatology. https://doi.org/10.1002/art.40731
Comment/debate
Sheriff, L, Copland, A & Bending, D 2023, 'T cell biomarkers come to the fore in cancer immunotherapy', Cell Reports Medicine, vol. 4, no. 4, 100989. https://doi.org/10.1016/j.xcrm.2023.100989
Review article
Bending, D & Zikherman, J 2023, 'Nr4a nuclear receptors: markers and modulators of antigen receptor signaling', Current Opinion in Immunology, vol. 81, 102285. https://doi.org/10.1016/j.coi.2023.102285
Working paper
Elliot, TAE, Jennings, EK, Lecky, DAJ, Thawait, N, Flores-Langarica, A, Wraith, DC & Bending, D 2021 'Antigen and checkpoint receptor recalibration of T cell receptor signal strength' bioRxiv, pp. 1-48. https://doi.org/10.1101/2021.03.02.431957
View all publications in research portal