Dr Majid Malboubi BSc, MSc, PhD, FHEA

Dr Majid Malboubi

Department of Mechanical Engineering
Dubai Campus Head of Quality Assurance Assistant Professor of Mechanical Engineering

Contact details

Address
Department of Mechanical Engineering
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Dr Majid Malboubi is an assistant professor in Mechanical Engineering.

Inspired by the workings of nature, Dr Malboubi applies the principles of mechanics and design micro-tools to unravel the physics underlying cellular processes and to understand how cells interact with their surroundings. Dr Malboubi completed his PhD at the University of Birmingham and worked on the interaction of biological membranes with solid substrates, and published several articles on this subject, as well as a book (Gigaseal formation in patch clamping, Springer, 2014).

Upon moving to the London Centre of Nanotechnology at UCL, Dr Malboubi worked on the poroelasticity and pressure propagation in cells to explain cells’ ability to sustain transient and prolonged pressure gradients across their cytoplasm in response to extrinsic and intrinsic mechanical stresses. 

Dr Malboubi also developed several microfluidic devices for cancer metastasis and drug screening. Subsequently, Dr Malboubi moved to the University of Oxford to investigate the effects of mechanical loadings, such as compression or stretch on neural electrophysiological responses and the ability of neurons to fire action potentials after trauma.

Qualifications

  • 2019 – 2021 Postgraduate Certificate in Higher Education, University of Birmingham 
  • 2020 Fellow of the Higher Education Academy (FHEA)
  • 2007 – 2011 PhD in Mechanical Engineering, University of Birmingham 

Biography

02/2020 – Present         Head of Quality Assurance, University of Birmingham Dubai

06/2018 – Present         Assistant Professor, Department of Mechanical Engineering, University of Birmingham

05/2016 – 05/2018        Researcher Co-Investigator, Department of Engineering Science, University of Oxford

07/2014 – 05/2016         Postdoctoral Researcher, Institute of Biomedical Engineering, University of Oxford

10/2011 – 07/2014         Postdoctoral Researcher, London Centre for Nanotechnology, University College London

Teaching

  • Mechanics
  • Fluid Mechanics
  • Energy Transfer and Thermodynamics
  • Mechanical Design
  • Manufacturing
  • Mechanics Laboratory
  • Fluid Mechanics Laboratory

Research

  • Gigaseal formation
  • Microfluidics 
  • Cell and tissue mechanics
  • Substrate-Membrane interactions
  • 3D Printing

Funding

  • EPSRC Healthcare Technologies Challenge Awards. Electrophysiological-mechanical coupled pulses in neural membranes: a new paradigm for clinical therapy of SCI and TBI (NeuroPulse), £991,283, [EP/N020987/1], Co-Investigator.

Other activities

Memberships

  • Member of Advance HE
  • Member of Biophysical Society
  • Member of International Association of Engineers
  • Member of The Marine Biological Association (2016 – 2018)
  • Member of The Royal Microscopical Society (2010 – 2016)

 Reviewer

  • Member of Topical Advisory Panel of Micromachines journal

Publications

Book

Book Chapter

Journal Articles

Conference Papers

  • Malboubi M, Ostadi H, Wang S, Gu Y, Jiang K. The effect of pipette tip roughness on gigaseal formation (pdf). The 2009 International Conference of Systems Biology and Bioengineering, World Congress on Engineering. 1-3 July 2009 London. 1849-1852.
  • Malboubi M, Shakeri M, Bakhshi M. Design and fabrication of a prototype two-component strain gauge based grinding dynamometer. International Conference on Advances in Materials and Processing Technologies, 30 July - 01 August 2006 Las Vegas
  • Malboubi M, and Shakeri M. Machine tools with parallel structure and their calibration methods. The 13th International Conference on Mechanical Engineering, 17-19 May 2005 Esfahan
  • Malboubi M, Jerusalem A. Experimental multi-physics measurement of neuronal responses under trauma, Biophysical Journal, 110(2), 149a, 2016
  • Malboubi M, Jayo A, Parsons M, Charras M. An open access microfluidic device for the study of cancer cell deformation during migration. 40th International Conference on Micro Nano Engineering, 22 – 26 September 2014, Lausanne
  • Bove A, Malboubi M, Lowe A, Charras G. A microfluidic device for studying cancer cells competition under controlled conditions. 40th International Conference on Micro Nano Engineering, 22 – 26 September 2014, Lausanne
  • Davies J, Malboubi M, Ivetic A, Charras G. A microfluidic chip to model leukocyte inflammatory responses. 40th International Conference on Micro Nano Engineering, 22-26 September 2014, Lausanne
  • Malboubi M, Behroozi M, Bowen J, Chizari M, Charras G, Jiang K. The effect of aperture size on gigaseal formation. Biophysical Journal, 104(2), 673a, 2013
  • Malboubi M, Gu Y, Jiang K. Surface property characterization of glass micropipettes using SEM stereoscopic technique. 36th International Conference on Micro Nano Engineering, 19-22 September 2010 Genoa
  • Mohammadkhani M, Malboubi M, Anthony C, Jiang K. 3D-reconstruction of nanostructures made by nanosphere lithography using SEM stereoscopic technique. 36th International Conference on Micro Nano Engineering, 19-22 September 2010 Genoa
  • Malboubi M, Gu Y, Jiang K. Investigation of pipette roughness effects on seal formation in patch clamping. 35th International Conference on Micro Nano Engineering, 28 September - 01 October 2009 Ghent
  • Ostadi H, Malboubi M, Jiang K, Prewett P. FIB/SEM Nano-Tomography of a micropipette. 34th International Conference on Micro Nano Engineering, 15-18 September 2008 Athens

View all publications in research portal