Professor Iseult Lynch PhD, MBA

Professor Iseult Lynch

School of Geography, Earth and Environmental Sciences
Professor of Environmental Nanosciences
Theme lead for Environmental Sciences

Contact details

Address
School of Geography, Earth and Environmental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Professor Iseult Lynch, Chair of Environmental Nanosciences, joined the academic staff at the University of Birmingham in March 2013.

She is an Associate Editor for Environmental Science: Nano, and Deputy director for the Facility for Environmental Nanomaterials Analysis and Characterisation (FENAC) at the University of Birmingham.  Her research focuses on the environmental interactions of nanoparticles and nanostructured surfaces with biological entities from macromolecules to organisms.

She has a very broad overview of all aspects of nanomaterials safety assessment and the data requirements, having served as Chair of the EU Nanosafety Cluster Working Group (NSC WG) on databases for two years (and as co-Chair of the Hazed WG prior to that), as well as being theme editor for the Materials and classification section of the NSC Vision2020 research roadmap (under review for publication in June 2013). Prior to the University of Birmingham she was Strategic Research Manager at the Centre for BioNano Interactions in University College Dublin, where she was instrumental in the development and implementation of numerous large EU-funded projects.

Iseult is part of the Birmingham Plastics Network, an interdisciplinary team of more than 40 academics working together to shape the fate and sustainable future of plastics.  This unique team brings together chemists, environmental scientists, philosophers, linguists, economists, and experts in many other fields, to holistically address the global plastics problem.

Qualifications

BSc. (Hons) Chemistry (1995)

PhD (Chemistry, 2000)

MBA (2012)

Teaching

Professor Lynch is the undergraduate admissions tutor for Environmental Science.

Leads and contributes to undergraduate modules on the following topics:

  • molecules and materials
  • environmental protection
  • environmental pollution

Deputy director of the MRes in Biological and Environmental Nanoscience, and module leader for the MRes module 'Biological and Environmental Nanoscience'.

Postgraduate supervision

Dr Lynch’s research interests include:

Synthesis of novel composite polymeric materials for biomaterials and environmental applications
Nanoparticle interactions with biomolecules in the environment (natural organic matter, secreted proteins, organic pollutants, etc.) - the “eco-corona” and secondary pollutant effects
Determination of the fate and behavior of nanomaterials in the environment
Development of high throughput screening applications: nano(eco)toxicology, bionanointeractions and assessment of environmental fate of nanomaterials

Research

Understanding the role of the bio-nano interface, and interactions with biomolecules, in determining nanoparticle fate and behaviour in the environment and for human health.

Other activities

Publications

Recent publications

Article

Mouchlis, VD, Afantitis, A, Serra, A, Fratello, M, Papadiamantis, AG, Aidinis, V, Lynch, I, Greco, D & Melagraki, G 2021, 'Advances in De Novo Drug Design: From Conventional to Machine Learning Methods', International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22041676

Nel, HA, Chetwynd, AJ, Kelleher, L, Lynch, I, Mansfield, I, Margenat, H, Onoja, S, Goldberg Oppenheimer, P, Sambrook Smith, GH & Krause, S 2021, 'Detection limits are central to improve reporting standards when using Nile red for microplastic quantification', Chemosphere, vol. 263, 127953, pp. 1-9. https://doi.org/10.1016/j.chemosphere.2020.127953

Saarimäki, LA, Federico, A, Lynch, I, Papadiamantis, AG, Tsoumanis, A, Melagraki, G, Afantitis, A, Serra, A & Greco, D 2021, 'Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials', Scientific Data, vol. 8, no. 1, 49. https://doi.org/10.1038/s41597-021-00808-y

Monikh, FA, Chupani, L, Arenas-Lago, D, Guo, Z, Zhang, P, Darbha, GK, Valsami-Jones, E, Lynch, I, Vijver, MG, Bodegom, PMV & Peijnenburg, WJGM 2021, 'Particle number-based trophic transfer of gold nanomaterials in an aquatic food chain', Nature Communications, vol. 12, no. 1, 899. https://doi.org/10.1038/s41467-021-21164-w

Quevedo, AC, Lynch, I & Valsami-Jones, E 2021, 'Silver nanoparticle induced toxicity and cell death mechanisms in embryonic zebrafish cells', Nanoscale, vol. 13, no. 12, pp. 6142-6161. https://doi.org/10.1039/d0nr09024g

Kraftl, P, Lynch, I, Jarman, P, Menzel, A, Walker, A, Till, R & Hadfield-Hill, S 2021, 'So you’re literally taking the piss?! Critically analysing and accounting for ethics (and risk) in interdisciplinary research on children and plastics', Children's Geographies. https://doi.org/10.1080/14733285.2021.1875124

Zhang, P, Wu, X, Guo, Z, Yang, X, Hu, X & Lynch, I 2021, 'Stress Response and Nutrient Homeostasis in Lettuce (Lactuca sativa) Exposed to Graphene Quantum Dots Are Modulated by Particle Surface Functionalization', Advanced Biology, pp. 2000778. https://doi.org/10.1002/adbi.202000778

Bobyk, L, Tarantini, A, Beal, D, Veronesi, G, Kieffer, I, Motellier, S, Valsami-Jones, E, Lynch, I, Jouneau, P-H, Pernet-Gallay, K, Aude-Garcia, C, Sauvaigo, S, Douki, T, Rabilloud, T & Carriere, M 2021, 'Toxicity and chemical transformation of silver nanoparticles in A549 lung cells: dose-rate-dependent genotoxic impact', Environmental Science: Nano, vol. 2021, no. 00, pp. 1-16. https://doi.org/10.1039/D0EN00533A

Khodaparast, Z, van Gestel, CAM, Papadiamantis, AG, Gonçalves, SF, Lynch, I & Loureiro, S 2021, 'Toxicokinetics of silver nanoparticles in the mealworm Tenebrio molitor exposed via soil or food', Science of the Total Environment, vol. 777, 146071. https://doi.org/10.1016/j.scitotenv.2021.146071

Ammar, A, Bonaretti, S, Winckers, L, Quik, J, Bakker, M, Maier, D, Lynch, I, Rijn, JV & Willighagen, E 2020, 'A Semi-Automated Workflow for FAIR Maturity Indicators in the Life Sciences', Nanomaterials, vol. 10, no. 10, 2068, pp. 1-14. https://doi.org/10.3390/nano10102068

Halappanavar, S, Ede, JD, Mahapatra, I, Krug, HF, Kuempel, ED, Lynch, I, Vandebriel, RJ & Shatkin, JA 2020, 'A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment', Nanotoxicology, pp. 1-24. https://doi.org/10.1080/17435390.2020.1851419

Xu, Y, Wang, W, Ma, L, Cui, X, Lynch, I & Wu, G 2020, 'Acute toxicity of Zinc Oxide nanoparticles to silkworm (Bombyx mori L.)', Chemosphere, vol. 259, pp. 127481. https://doi.org/10.1016/j.chemosphere.2020.127481

Editorial

Lynch, I, Afantitis, A, Greco, D, Dusinska, M, Banares, MA & Melagraki, G 2021, 'Editorial for the special issue From Nanoinformatics to Nanomaterials Risk Assessment and Governance', Nanomaterials, vol. 11, no. 1, 121. https://doi.org/10.3390/nano11010121

Review article

Krause, S, Baranov, V, Nel, HA, Drummond, JD, Kukkola, A, Hoellein, T, Sambrook Smith, GH, Lewandowski, J, Bonnet, B, Packman, AI, Sadler, J, Inshyna, V, Allen, S, Allen, D, Simon, L, Mermillod-Blondin, F & Lynch, I 2021, 'Gathering at the top? Environmental controls of microplastic uptake and biomagnification in freshwater food webs', Environmental Pollution, vol. 268, no. Pt A, 115750. https://doi.org/10.1016/j.envpol.2020.115750

Kukkola, A, Krause, S, Lynch, I, Sambrook Smith, GH & Nel, H 2021, 'Nano and microplastic interactions with freshwater biota - Current knowledge, challenges and future solutions', Environment International, vol. 152, 106504. https://doi.org/10.1016/j.envint.2021.106504

View all publications in research portal

Expertise

Nanomaterials in the environment (as well as food, cosmetics, consumer products, nanomedicines, nanopesticides etc.); nanomaterials transformations; nanomaterials fate and behaviour; nanomaterials eco/toxicology; Nanosafety assessment; nanoregulation; nanogovernance; Microplastics; nanoplastics; Open data