Professor Iseult Lynch PhD, MBA

Professor Iseult Lynch

School of Geography, Earth and Environmental Sciences
Professor of Environmental Nanosciences
Theme lead for Environmental Sciences

Contact details

Address
School of Geography, Earth and Environmental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Professor Iseult Lynch, Chair of Environmental Nanosciences, joined the academic staff at the University of Birmingham in March 2013.

She is an Associate Editor for Environmental Science: Nano, and Deputy director for the Facility for Environmental Nanomaterials Analysis and Characterisation (FENAC) at the University of Birmingham.  Her research focuses on the environmental interactions of nanoparticles and nanostructured surfaces with biological entities from macromolecules to organisms.

She has a very broad overview of all aspects of nanomaterials safety assessment and the data requirements, having served as Chair of the EU Nanosafety Cluster Working Group (NSC WG) on databases for two years (and as co-Chair of the Hazed WG prior to that), as well as being theme editor for the Materials and classification section of the NSC Vision2020 research roadmap (under review for publication in June 2013). Prior to the University of Birmingham she was Strategic Research Manager at the Centre for BioNano Interactions in University College Dublin, where she was instrumental in the development and implementation of numerous large EU-funded projects.

Qualifications

BSc. (Hons) Chemistry (1995)

PhD (Chemistry, 2000)

MBA (2012)

Teaching

Professor Lynch is the undergraduate admissions tutor for Environmental Science.

Leads and contributes to undergraduate modules on the following topics:

  • molecules and materials
  • environmental protection
  • environmental pollution

Deputy director of the MRes in Biological and Environmental Nanoscience, and module leader for the MRes module 'Biological and Environmental Nanoscience'.

Postgraduate supervision

Dr Lynch’s research interests include:

Synthesis of novel composite polymeric materials for biomaterials and environmental applications
Nanoparticle interactions with biomolecules in the environment (natural organic matter, secreted proteins, organic pollutants, etc.) - the “eco-corona” and secondary pollutant effects
Determination of the fate and behavior of nanomaterials in the environment
Development of high throughput screening applications: nano(eco)toxicology, bionanointeractions and assessment of environmental fate of nanomaterials

Research

Understanding the role of the bio-nano interface, and interactions with biomolecules, in determining nanoparticle fate and behaviour in the environment and for human health.

Other activities

Publications

Recent publications

Article

Carrazco-Quevedo, A, Römer, I, Salamanca, MJ, Poynter, A, Lynch, I & Valsami-Jones, E 2019, 'Bioaccumulation and toxic effects of nanoparticulate and ionic silver in Saccostrea glomerata (rock oyster)', Ecotoxicology and Environmental Safety, vol. 179, pp. 127-134. https://doi.org/10.1016/j.ecoenv.2019.04.032

Briffa, SM, Lynch, I, Hapiuk, D & Valsami-Jones, E 2019, 'Physical and chemical transformations of zirconium doped ceria nanoparticles in the presence of phosphate: increasing realism in environmental fate and behaviour experiments', Environmental Pollution, vol. 252, no. Part B, pp. 974-981. https://doi.org/10.1016/j.envpol.2019.06.014

Grintzalis, K, Lawson, TN, Nasser, F, Lynch, I & Viant, MR 2019, 'Metabolomic method to detect a metabolite corona on amino-functionalized polystyrene nanoparticles', Nanotoxicology, vol. 13, no. 6, pp. 783-794. https://doi.org/10.1080/17435390.2019.1577510

Cui, X, Fryer, B, Zhou, D, Lodge, RW, Khlobystov, AN, Valsami-Jones, E & Lynch, I 2019, 'Core-Shell NaHoF4@TiO2 NPs: a labeling method to trace engineered nanomaterials of ubiquitous elements in the environment', ACS Applied Materials & Interfaces, vol. 11, no. 21, pp. 19452-19461. https://doi.org/10.1021/acsami.9b03062

Joossens, E, Macko, P, Palosaari, T, Gerloff, K, Ojea-Jiménez, I, Gilliland, D, Novak, J, Fortaner Torrent, S, Gineste, J-M, Römer, I, Briffa, SM, Valsami-Jones, E, Lynch, I & Whelan, M 2019, 'A high throughput imaging database of toxicological effects of nanomaterials tested on HepaRG cells', Scientific Data, vol. 6, no. 1, 46. https://doi.org/10.1038/s41597-019-0053-2

Zhang, P, Ma, Y, Xie, C, Guo, Z, He, X, Valsami-Jones, E, Lynch, I, Luo, W, Zheng, L & Zhang, Z 2019, 'Plant species-dependent transformation and translocation of ceria nanoparticles', Environmental Science: Nano, vol. 6, no. 1, pp. 60-67 . https://doi.org/10.1039/C8EN01089G

Tibbetts, J, Krause, S, Lynch, I & Sambrook-Smith, G 2018, 'Abundance, distribution, and drivers of microplastic contamination in urban river environments', Water, vol. 10, no. 11, 1597. https://doi.org/10.3390/w10111597

Dekkers, S, Ma-Hock, L, Lynch, I, Russ, M, Miller, MR, Schins, RPF, Keller, J, Römer, I, Küttler, K, Strauss, V, De Jong, WH, Landsiedel, R & Cassee, FR 2018, 'Differences in the toxicity of cerium dioxide nanomaterials after inhalation can be explained by lung deposition, animal species and nanoforms', Inhalation Toxicology. https://doi.org/10.1080/08958378.2018.1516834

Afantitis, A, Melagraki, G, Tsoumanis, A, Valsami-Jones, E & Lynch, I 2018, 'A nanoinformatics decision support tool for the virtual screening of gold nanoparticle cellular association using protein corona fingerprints', Nanotoxicology. https://doi.org/10.1080/17435390.2018.1504998

Mahapatra, I, Clark, JRA, Dobson, PJ, Owen, R, Lynch, I & Lead, JR 2018, 'Expert perspectives on potential environmental risks from nanomedicines and adequacy of the current guideline on environmental risk assessment', Environmental Science: Nano, vol. 5, no. 8, pp. 1873-1889. https://doi.org/10.1039/C8EN00053K

Markiewicz, M, Kumirska, J, Lynch, I, Matzke, M, Köser, J, Bemowsky, S, Docter, D, Stauber, R, Westmeier, D & Stolte, S 2018, 'Changing environments and biomolecule coronas: consequences and challenges for the design of environmentally acceptable engineered nanoparticles', Green Chemistry, vol. 20, no. 18, pp. 4133-4168. https://doi.org/10.1039/c8gc01171k

Briffa, SM, Lynch, I, Trouillet, V, Bruns, M, Hapiuk, D & Valsami-Jones, E 2018, 'Thermal Transformations of Manufactured Nanomaterials as a Proposed Proxy for Ageing', Environmental Science: Nano, vol. 5, no. 7, pp. 1618-1627. https://doi.org/10.1039/C7EN00738H

Editorial

Haase, A & Lynch, I 2018, 'Quality in nanosafety — Towards reliable nanomaterial safety assessment', NanoImpact, vol. 11, pp. 67-68. https://doi.org/10.1016/j.impact.2018.02.005

Review article

Riediker, M, Zink, D, Kreyling, W, Oberdörster, G, Elder, A, Graham, U, Lynch, I, Duschl, A, Ichihara, G, Ichihara, S, Kobayashi, T, Hisanaga, N, Umezawa, M, Cheng, T-J, Handy, R, Gulumian, M, Tinkle, S & Cassee, F 2019, 'Particle toxicology and health - where are we?', Particle and Fibre Toxicology, vol. 16, no. 1, 19. https://doi.org/10.1186/s12989-019-0302-8

Fadeel, B, Farcal, L, Hardy, BJ, Vázquez-Campos, S, Hristozov, D, Marcomini, A, Lynch, I, Valsami-Jones, E, Alenius, H & Savolainen, K 2018, 'Advanced tools for the safety assessment of nanomaterials', Nature Nanotechnology, vol. 13, no. 7, pp. 537-543. https://doi.org/10.1038/s41565-018-0185-0

View all publications in research portal

Expertise

Nanomaterials in the environment (as well as food, cosmetics, consumer products, nanomedicines, nanopesticides etc.); nanomaterials transformations; nanomaterials fate and behaviour; nanomaterials eco/toxicology; Nanosafety assessment; nanoregulation; nanogovernance; Microplastics; nanoplastics; Open data