Dr Zhiling Guo PhD

Dr Zhiling Guo

School of Geography, Earth and Environmental Sciences
Assistant Professor

Contact details

School of Geography, Earth and Environmental Sciences
University of Birmingham
B15 2TT

Dr. Zhiling Guo is an environmental toxicologist interested in understanding the connection between human exposure to pollutants (nanomaterial, micro/nano-plastic, air pollutant, organic pollutant, heavy metal, virus, pollen, and emerging pollutants) and life-long health, and the potential underlying mechanisms. Her research also focuses on establishing the 3R alternatives (i.e. in vitro barrier model, organ-on-chip) as enabling technologies to facilitate investigation of the human and environmental impacts of pollution, and to link across different research areas. She is also interested in understanding the effects of pollutants on ecosystems (terrestrial, aquatic, and marine ecosystem), and developing biosensors to detect the traditional and emerging pollutants in the environmental and biological samples.

She has multidisciplinary expertise in different areas including environmental health, material science, environmental toxicology, molecular toxicology, neurotoxicology, nanotoxicology, and aquatic toxicology. She has published over 50 papers in top-tier journals including Nature Protocol, Nature Plants, Nature Communication, PNAS, Water Research, ES&T, Nano Today, ES&T letter, etc. She is an Associate Editor for journal Frontiers in Toxicology and Guest Editor for Ecotoxicology and Environmental Safety.



  • BSc. Biotechnology (2008)
  • PhD Marine Ecology (2014)


  • BSc Environmental Sciences
  • Global Challenge in the Anthropocene
  • From molecules to materials: Deconstructing the environment

Other activities

  • Outstanding reviewer for Environmental Science: Nano
  • Associate Editor for Frontiers in Toxicology
  • Guest Editor for Ecotoxicology and Environmental Safety
  • Editorial Board member for Ecotoxicology and Environmental Safety
  • Full Member of Society of Toxicology
  • Member of Society of Environmental Toxicology and Chemistry
  • Full Member of Chinese Society of Toxicology


Recent publications


An, C, Huang, B, Jiang, J, Wang, X, Li, N, Liu, H, Shen, Y, Sun, C, Zhan, S, Li, X, Wang, C, Zeng, Z, Cui, H, Wu, Q, Zhang, Y, Guo, Z, Zhang, P, Lynch, I, Gao, J-M & Wang, Y 2024, 'Design and Synthesis of a Water-Based Nanodelivery Pesticide System for Improved Efficacy and Safety', ACS Nano, vol. 18, no. 1, pp. 662-679. https://doi.org/10.1021/acsnano.3c08854

Li, M, Zhang, P, Guo, Z, Zhao, W, Li, Y, Yi, T, Cao, W, Gao, L, Tian, CF, Chen, Q, Ren, F, Rui, Y, White, JC & Lynch, I 2024, 'Dynamic Transformation of Nano-MoS2 in a Soil-Plant System Empowers Its Multifunctionality on Soybean Growth', Environmental Science and Technology, vol. 58, no. 2, pp. 1211-1222. https://doi.org/10.1021/acs.est.3c09004

Yang, K, Wang, X, Lynch, I, Guo, Z, Zhang, P & Wu, L 2024, 'Green construction of MBI corrosion-resistant interfaces modified NZVI@MOFs-regulated 3D PAN cryogel film to enhance Cr(VI) removal', Separation and Purification Technology, vol. 333, 125902. https://doi.org/10.1016/j.seppur.2023.125902

Deng, Y, Wang, X, Lynch, I, Guo, Z, Zhang, P, Wu, L, Wu, X & Li, T 2024, 'Homogeneous dispersion of amorphous nanoscale zero-valent iron supported on chlorella-derived biochar: In-situ synthesis and application mechanism for Cr(VI) removal over a wide pH range', Separation and Purification Technology, vol. 330, 125207. https://doi.org/10.1016/j.seppur.2023.125207

Song, Z, Dang, X, Zhao, L, Hou, H, Guo, Z, Lynch, I, Nadezhda, T & Zhang, P 2024, 'Influence of soil properties and aging on exogenous antimony toxicity to Caenorhabditis elegans in agricultural soil', Environmental Science and Pollution Research, vol. 31, no. 8, pp. 12499-12510. https://doi.org/10.1007/s11356-024-31975-1

Wang, X, Jiang, M, Lynch, I, Guo, Z, Zhang, P, Wu, L & Ma, J 2023, 'Construction of urchin-like core-shell Fe/Fe2O3@UiO-66 hybrid for effective tetracycline reduction and photocatalytic oxidation', Environmental Pollution, vol. 336, 122280. https://doi.org/10.1016/j.envpol.2023.122280

Guo, Z, Zhang, P, Xie, C, Voyiatzis, E, Faserl, K, Chetwynd, AJ, Monikh, FA, Melagraki, G, Zhang, Z, Peijnenburg, WJGM, Afantitis, A, Chen, C & Lynch, I 2023, 'Defining the Surface Oxygen Threshold That Switches the Interaction Mode of Graphene Oxide with Bacteria', ACS Nano, vol. 17, no. 7, pp. 6350-6361. https://doi.org/10.1021/acsnano.2c10961

Yang, K, Wang, X, Lynch, I, Guo, Z, Zhang, P, Wu, L & Ma, J 2023, 'Design of cryogel based CNTs-anchored polyacrylonitrile honeycomb film with ultra-high S-NZVI incorporation for enhanced synergistic reduction of Cr(VI)', Journal of Hazardous Materials, vol. 442, 129923. https://doi.org/10.1016/j.jhazmat.2022.129923

Wu, X, Wang, X, Lynch, I, Guo, Z, Zhang, P, Wu, L, Ning, P & Ren, N 2023, 'Exceptional photo-elimination of antibiotic by a novel Z-scheme heterojunction catalyst composed of nanoscale zero valent iron embedded with carbon quantum dots (CQDs)-black TiO2', Journal of Hazardous Materials, vol. 460, 132323. https://doi.org/10.1016/j.jhazmat.2023.132323

Xie, C, Li, X, Guo, Z, Dong, Y, Zhang, S, Li, A, Ma, S, Xu, J, Pang, Q, Peijnenburg, WJGM, Lynch, I & Zhang, P 2023, 'Graphene oxide disruption of homeostasis and regeneration processes in freshwater planarian Dugesia japonica via intracellular redox deviation and apoptosis', Ecotoxicology and Environmental Safety, vol. 249, 114431. https://doi.org/10.1016/j.ecoenv.2022.114431

Review article

Zhang, P, Jiang, Y, Schwab, F, Monikh, FA, Grillo, R, White, JC, Guo, Z & Lynch, I 2024, 'Strategies for Enhancing Plant Immunity and Resilience Using Nanomaterials for Sustainable Agriculture', Environmental Science and Technology, vol. 58, no. 21, pp. 9051-9060. https://doi.org/10.1021/acs.est.4c03522

Li, X, Chen, Y, Xu, J, Lynch, I, Guo, Z, Xie, C & Zhang, P 2023, 'Advanced nanopesticides: Advantage and action mechanisms', Plant physiology and biochemistry : PPB, vol. 203, 108051. https://doi.org/10.1016/j.plaphy.2023.108051

Reilly, K, Bradford, L, Davoudi, HH, Supian, S, Maia, MT, Silva, GH, Guo, Z, Martinez, DST & Lynch, I 2023, 'Daphnia as a model organism to probe biological responses to nanomaterials—from individual to population effects via adverse outcome pathways', Frontiers in toxicology, vol. 5, 1178482. https://doi.org/10.3389/ftox.2023.1178482

Li, X, Chen, Y, Zhang, S, Dong, Y, Pang, Q, Lynch, I, Xie, C, Guo, Z & Zhang, P 2023, 'From marine to freshwater environment: A review of the ecotoxicological effects of microplastics', Ecotoxicology and Environmental Safety, vol. 251, 114564. https://doi.org/10.1016/j.ecoenv.2023.114564

Ali, A, Javed, R, Farhangi, S, Shah, T, Ullah, S, ul Ain, N, Liu, T, Guo, Z, Lynch, I, Raza, F, Zhang, P & Rui, YK 2023, 'Metal phenolic networks (MPNs)-based pH-sensitive stimulus responsive nanosystems for drug delivery in tumor microenvironment', Journal of Drug Delivery Science and Technology, vol. 84, 104536. https://doi.org/10.1016/j.jddst.2023.104536

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