Ms Janine Dretzke

Janine Dretzke

Institute of Applied Health Research
Senior Systematic Reviewer

Contact details

Biostatistics, Evidence Synthesis and Test Evaluation (BESaTE)
University of Birmingham
B15 2TT

Janine has considerable experience in conducting evidence syntheses, systematic reviews, meta-analyses and health technology assessments (HTA) to inform local and national healthcare decision making. Research outputs include reports commissioned by the National Institute for Health and Care Excellence (NICE) and the NIHR Health Technology Assessment (HTA) Programme. Janine has an interest in evidence synthesis methodologies as applied to different types of health care questions and study designs (e.g. effectiveness, test accuracy, adverse events, prognostic factors and models).  Janine lectures in study design and the methodology of undertaking evidence syntheses and is a module coordinator of the Systematic Reviews and Evidence Synthesis module (MPH (HTA)).


  • MSc Health Technology Assessment (University of Birmingham 2003)
  • MSc Environmental Management (University of Stirling 1996)
  • BSc Biological Sciences with Microbiology (University of Warwick 1995)


Other activities

Module coordinator for the Systematic Reviews and Evidence Synthesis Module of the MPH (HTA)


Recent publications


Dretzke, J, Wang, J, Yao, M, Guan, N, Ling, M, Zhang, E, Mukherjee, D, Hall, J, Jowett, S, Mukherjee, R, Moore, DJ & Turner, AM 2022, 'Home non-invasive ventilation in COPD: a global systematic review', Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, vol. 9, no. 2, pp. 237-251.

Hall, J, Turner, A, Dretzke, J, Moore, D & Jowett, S 2021, 'Cost-effectiveness of domiciliary non-invasive ventilation in patients with chronic obstructive pulmonary disease', Thorax.

Cochrane COVID-19 Diagnostic Test Accuracy Group 2021, 'Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection', Cochrane Database of Systematic Reviews, vol. 2021, no. 3, CD013705.

Deeks, J, Dinnes, J, Takwoingi, Y, Davenport, C, Spijker, R, Taylor-Phillips, S, Adriano, A, Beese, S, Dretzke, J, Ferrante di Ruffano, L, Harris, I, Price, M, Dittrich, S, Emperador, D, Hooft, L, Leeflang, MMG, Van De Bruel, A, McInnes, MDF, Stuyf, T, Domen, J, Horn, S, Yang, B, Langendam, M, Ochodo, E, Guleid, F, Holtman, G, Verbakel, J, Wang, J, Stegeman, I, Salameh , JP, McGrath , TA, van der Pol , CB, Frank , RA, Prager , R, Hare , SS, Dennie , C, Jenniskens, K, Korevaar , DA, Cohen , JF, van de Wijgert, J, Damen , JAAG, Agarwal, R, Baldwin, S, Berhane, S, Herd, C, Kristunas, C, Quinn, L & Scholefield, B 2020, 'Antibody tests for identification of current and past infection with SARS-CoV-2', Cochrane Library, vol. 2020, no. 6, CD013652.

Dretzke, J, Chuchu, N, Agarwal, R, Herd, C, Chua, WWL, Fabritz, L, Bayliss, S, Kotecha, D, Deeks, J, Kirchhof, P & Takwoingi, Y 2020, 'Predicting recurrent atrial fibrillation after catheter ablation: a systematic review of prognostic models', Europace, vol. 22, no. 5, pp. 748–760.

Harris, IM, Lee, KC, Deeks, J, Moore, D, Moiemen, N & Dretzke, J 2020, 'Pressure‐garment therapy for preventing hypertrophic scarring after burn injury', Cochrane Database of Systematic Reviews, vol. 2020, no. 1, CD013530.

Cochrane COVID-19 Diagnostic Test Accuracy Group, Dinnes, J, Deeks, J, Adriano, A, Berhane, S, Davenport, C, Dittrich, S, Emperador, D, Takwoingi, Y, Cunningham , J, Beese, S, Dretzke, J, Ferrante di Ruffano, L, Harris, I, Price, M, Taylor-Phillips, S, Hooft, L, Leeflang, MMG, Spijker, R & Van De Bruel, A 2020, 'Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection (Review)', Cochrane Database of Systematic Reviews, no. 8, CD013705. 10.1002/14651858.CD013705.

Malouf, R, Tomlinson, C, Henderson, J, Opondo, C, Brocklehurst, P, Alderdice, F, Phalguni, A & Dretzke, J 2020, 'The impact of obstetric unit closures, travel time and distance to obstetric services on maternal and neonatal outcomes in high-income countries: a systematic review', BMJ open.

Beese, S, Harris, I, Dretzke, J & Moore, D 2019, 'Body image dissatisfaction in patients with inflammatory bowel disease: a systematic review', BMJ Open Gastroenterology, vol. 6, no. 1, e000255.

Dretzke, J, Chuchu, N, Chua, W, Fabritz, L, Bayliss, S, Kotecha, D, Deeks, JJ, Kirchhof, P & Takwoingi, Y 2019, 'Prognostic models for predicting incident or recurrent atrial fibrillation: protocol for a systematic review', Systematic Reviews, vol. 8, no. 1, 221.

Nieto, T, Smith, C, Dretzke, J, Bayliss, S, Price, M, Dilworth, M, Beggs, AD & Tucker, O 2018, 'A systematic review of epigenetic biomarkers in progression from non-dysplastic Barrett’s oesophagus to oesophageal adenocarcinoma', BMJ open, vol. 8, e020427.

Beese, S, Harris, I, Moore, D & Dretzke, J 2018, 'Body image dissatisfaction in patients with inflammatory bowel disease: a systematic review protocol', BMC Systematic Reviews, vol. 7, 184.

Patel, V, Champaneria, R, Dretzke, J & Yeung, J 2018, 'Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review', BMJ open, vol. 8, no. 12, e020757.

Bennett, P, Stewart, SK, Dretzke, J, Bem, D & Penn-Barwell, JG 2018, 'Preclinical therapies to prevent or treat fracture non-union: a systematic review', PLoS ONE, vol. 13, no. 8, e0201077.

Review article

Farooq, S, Khandavilli, S, Dretzke, J, Moore, D, Nankivell, P, Sharma, N, de Almeida, JR, Winter, S, Simon, C, Paleri, V, De, M, Siddiq, S, Holsinger, C, Ferris, RL & Mehanna, H 2019, 'Transoral tongue base mucosectomy for the identification of the primary site in the work-up of cancers of unknown origin: systematic review and metaanalysis', Oral Oncology, vol. 91, pp. 97-106.

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