Dr Rachel Jordan MA (Cantab), MPH, PhD

Institute of Applied Health Research
Reader in Epidemiology and Primary Care

Contact details

Telephone: +44 (0)121 414 6775
Email: r.e.jordan@bham.ac.uk

Address: The Murray Learning Centre
Institute of Applied Health Research
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham, B15 2TT

Rachel Jordan is a Reader in Epidemiology & Primary Care. Her research focuses mainly on the early diagnosis, management and prognosis of COPD in the primary care setting.

She holds several NIHR grants including a £2.4m programme grant and a £2m Global Health Research Group grant. Rachel is the chair of the research committee of the International Primary Care Respiratory Group (IPCRG) and also the College Academic Lead for Global Health Research.

Other research interests include the effectiveness and uptake of both seasonal and pandemic influenza vaccine in different population groups.

She also teaches and supervises postgraduate and undergraduate students in Medicine and Public Health.

Qualifications

PhD in Epidemiology University of Birmingham, 2007
MPH University of Birmingham, 2000
MA (Cantab) Natural Sciences, University of Cambridge, 1993

Biography

Rachel Jordan qualified with a BA in Natural Sciences from the University of Cambridge (Emmanuel College) in 1993.

After a brief spell in the pharmaceutical industry she went on to take her first post in epidemiology at the Wolfson Institute of Preventive Medicine with Professors Nick Wald and Malcolm Law, undertaking a series of systematic reviews including one which led to the generation of the Polypill idea.

Returning to her home town of Birmingham in 1998, Rachel joined the systematic review team in Public Health & Epidemiology, gaining her MPH and being awarded the Thomas McKeown project prize. In 2000, although still based at the University of Birmingham, Rachel took up a research role with the Health Protection Agency, gaining her PhD part time over a 6-year period, and publishing further related papers, including 3 invited editorials in the BMJ. Most of her work during this period focussed on acute respiratory hospital admissions and the epidemiology of influenza and influenza vaccines.

Following completion of her PhD Rachel became a Lecturer with responsibility for helping to manage the MPH and moving to work more on chronic respiratory diseases, before in 2008 being awarded a research fellowship from the NIHR entitled “Towards a better understanding of the definition, characteristics and health service requirements of patients with COPD in the UK” comprising a series of studies using the Health Survey for England, the GPRD and published literature.

She was an integral part of a team of investigators awarded a £2m NIHR programme grant entitled “COPD in Primary Care: from case finding to improving patient outcomes, co-PI on an HTA-funded evidence review of the effectiveness of self-management for COPD and a key investigator on a number of other related primary and secondary research grants. In 2017 she was awarded an NIHR Global Health Research Group grant on COPD in primary care. Her recent trial “TargetCOPD” was awarded 2016 RCGP Research Paper of the Year for the respiratory category.

In 2011 she was promoted to Senior Lecturer and in 2018 to Reader.

Teaching

Teaching Programmes

IAHR Deputy Director of Teaching
MBChB years 1 & 3
Public Health MPH/PGDip/PGCert
MSc in Primary Care

Research

RESEARCH THEMES

COPD screening; COPD epidemiology (aetiology, prognosis and effectiveness of new interventions); COPD self-management; seasonal and pandemic influenza vaccine epidemiology; systematic reviews; epidemiological studies; health services research; global health

CURRENT PROJECTS

Rachel is the Co-Chief Investigator and Director of Breathe Well; an NIHR-funded Global Health Research Group on COPD in Primary Care (£2M; 2017-2020). The aim of the programme is to foster research in primary care and the community to improve the diagnosis, management and prognosis of COPD patients in low and middle income countries.

NIHR Programme Grant
COPD in Primary Care: from case finding to improving patient outcomes
2011-2018; £2.4m

PREVIOUS GRANTS

NIHR Post-doctoral Research Fellowship
Towards a better understanding of the definition, characteristics and health service requirements of patients with COPD in the UK
2008 – 2013; £337,041

HTA programme
Supported self-management for patients with moderate to severe chronic obstructive pulmonary disease (COPD): an evidence synthesis and economic analysis
2011-2013; £241,472.

HTA programme
The cost-effectiveness of community based non-invasive ventilation (NIV) in patients with stable end stage COPD with hypercapnic respiratory failure. A systematic review and economic evaluation
2012-2013; £213,264.

National Schools of Primary Care
Evaluation of the PiKo-6 as a novel screening test for case finding for COPD in primary care
Jan – Dec 2012: £58,957

National Schools of Primary Care
Patient self-management in primary care in patients with COPD
Jan 2013– Dec 2015: £802,000

National Schools of Primary Care
A pilot study to assess the prevalence and characteristics of emphysematous lung change in patients with symptoms of COPD and normal spirometry
Jan – Dec 2012: £50,000

NIHR HS&DR Programme
Enhancing the Health of NHS Staff: eTHOS. A randomised controlled pilot trial of an employee health screening clinic for NHS staff.
2018-2020; £701,136

NIHR HTA programme
Sputum colour charts to guide antibiotic self-treatment of acute exacerbation of COPD (Colour-COPD)
2019-2023; £2,056,942

Other activities

British Lung Foundation Research Committee

Publications

Jolly K, Sidhu M, Bates E, Majothi S, Sitch A, Bayliss S, Kim HJS, Jordan R. Systematic review of the effectiveness of community-based self-management interventions among primary care COPD patients. NPJ Primary Care Respiratory Medicine 2018;28. doi:10.1038/s41533-018-0111-9

Oshagbemi OA, Keene S, Driessen JHM, Jordan R, Wouters EFM, de Boer A, de Vries F, Franssen FME. Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013. Respiratory Medicine 2018; doi:10.1016/j.rmed.2018.09.010

Miller M, Haroon S, Jordan R, Sitch A, Dickens A, Enocson A, Fitzmaurice D, Adab P. Clinical characteristics of patients newly diagnosed with chronic obstructive pulmonary disease by the fixed ratio and lower limit of normal criteria: a cross-sectional analysis of the TargetCOPD trial. International Journal of Chronic Obstructive Pulmonary Disease 2018;13:1979—1986. doi:10.2147/COPD.S146914

Enocson A, Jolly K, Jordan R, Fitzmaurice D, Greenfield S, Adab P, Cheng K, Cooper BG, Daley A, Dickens A, O'Beirne-Elliman J, Haroon S, Jowett S, Kalirai K, Marsh J, Miller MR, Riley R, Stockley R, Turner A. Case-finding for COPD in Primary Care: A qualitative study of patients’ perspectives. International Journal of Chronic Obstructive Pulmonary Disease 2018;13:1623—1632. doi: 10.2147/COPD.S147718

Jolly K, Sidhu M, Hewitt C, Coventry PA, Daley A, Jordan R, Heneghan C, Singh S, Ives N, Adab P, Jowett S, Varghese J, Nunan D, Ahmed K, Dowson L, Fitzmaurice D. Patient self-management in primary care patients with mild COPD - a randomised controlled trial of telephone health coaching. BMJ 2018;361:k2241

Rai K, Adab P, Ayres J, Jordan R. Systematic review: Chronic obstructive pulmonary disease and work-related outcomes. Occupational Medicine 2018; doi 10.1093/occmed/kqy012

Brien SB, Stuart B, Dickens A, Kendrick A, Jordan R, Adab P, Thomas M. 2018. Independent determinants of disease-related quality of life in COPD - scope for non-pharmacological interventions?. International Journal of Chronic Obstructive Pulmonary Disease 2018; 13:247—256. doi: 10.2147/COPD.S152955

Khan, A., Dickens, A., Adab, P. & Jordan, R. Self-management behaviour and support among primary care COPD patients: Cross-sectional analysis of data from the Birmingham Chronic Obstructive Pulmonary Disease Cohort. NPJ Primary Care Respiratory Medicine. 2017; 27(1):46. doi: 10.1038/s41533-017-0046-62017.

Rai K, Adab P, Ayres JG, Jordan RE on behalf of the BLISS research team. Factors associated with work productivity among people with COPD: Birmingham COPD Cohort. Occup Environ Med Online First: 12 September 2017. doi: 10.1136/oemed-2016-104014

Haroon S, Adab P, Riley RD, Fitzmaurice DA, Jordan RE. Predicting risk of undiagnosed COPD: Development and validation of the TargetCOPD score. European Respiratory Journal 2017; 49: 1602191; DOI: 10.1183/13993003.02191-2016

Kosteli M-C, Heneghan N, Roskell C, Williams S, Adab P, Dickens A, Enocson A, Fitzmaurice D, Jolly C, Jordan R, Greenfield S & Cumming J. Barriers and enablers of physical activity engagement for patients with chronic obstructive pulmonary disease (COPD) in primary care. International Journal of Chronic Obstructive Pulmonary Disease. 2016; 12: 1019-1039.

Rai K, Jordan R, Siebert S, Sadhra S, Fitzmaurice D, Sitch A et al. Birmingham COPD Cohort: a cross-sectional analysis of the factors associated with the likelihood of being in paid employment among people with COPD. International Journal of Chronic Obstructive Pulmonary Disease. 2017; 12:233-242.

Dretzke J, Moore D, Dave C, Mukherjee R, Price M, Bayliss S, Jordan R & Turner A. The effect of domiciliary non-invasive ventilation (NIV) on clinical outcomes in stable and recently hospitalized patients with severe obstructive pulmonary disease (COPD): a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease. 2016 Sep 20;11(1):2269—2286. Available from, DOI: 10.2147/COPD.S104238

Jordan RE, Adab P, Sitch A, Enocson A, Blissett D, Jowett S, Marsh J, Riley RD, Miller MR, Cooper BG, Turner AM, Jolly C, Ayres JG, Haroon S, Stockley R, Greenfield S, Siebert W, Daley A, Cheng KK, Fitzmaurice DA. Targeted case finding for COPD versus routine practice in primary care (TargetCOPD): a cluster randomised controlled trial. The Lancet Respiratory Medicine 2016; 4(9):720-30.

Adab P, Fitzmaurice DA, Dickens AP, Ayres JG, Buni H, Cooper BG, Daley AJ, Enocson A, Greenfield S, Jolly K, Jowett S, Kalirai K, Marsh JL, Miller MR, Riley RD, Siebert WS, Stockley RA, Turner AM, Cheng KK, Jordan RE. Cohort Profile: The Birmingham Chronic Obstructive Pulmonary Disease (COPD) Cohort Study. International Journal of Epidemiology 2016; doi: 10.1093/ije/dyv350

Pinnock H, Steed E, Jordan RE. Supported self-management for chronic obstructive pulmonary disease: making progress, but there are still challenges. Invited editorial. Eur Respir J 2016 Jul;48(1):6-9. doi: 10.1183/13993003.00576-2016

Jolly K, Majothi S, Sitch A, Heneghan N, Moore D , Riley R, Bates E, Turner A, Bayliss S, Price M, Singh S, Adab P, Fitzmaurice D & Jordan RE. Self-management of health care behaviors for COPD: a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease. 2016; 11(1):305-326. Available from, DOI: 10.2147/COPD.S90812

Sidhu MS, Daley A, Jordan RE, Coventry PA, Heneghan C, Jowett S et al. Patient self-management in primary care patients with mild COPD - protocol of a randomised controlled trial of telephone health coaching. BMC Pulmonary Medicine. 2015 Feb 22;15. 16. Available from: 10.1186/s12890-015-0011-5

Dretzke J, Blissett D, Dave C, Mukherjee R, Price M, Bayliss S, Wu X, Jordan RE, Jowett S, Turner AM & Moore D. The cost-effectiveness of domiciliary non-invasive ventilation in patients with end-stage chronic obstructive pulmonary disease: a systematic review and economic evaluation. Health Technology Assessment 2015; 19(81); 1-246. 10.3310/hta19810

Haroon S, Jordan RE, Fitzmaurice DA & Adab P. Case finding for COPD in primary care: a qualitative study of the views of health professionals. International Journal of Chronic Obstructive Pulmonary Disease 2015; 10:1711-1718. 10.2147/COPD.S84247

Haroon SM, Jordan RE, O'Beirne-Elliman J & Adab P. Effectiveness of case finding strategies for COPD in primary care: a systematic review and meta-analysis. NPJ Primary Care Respiratory Medicine 2105; 25:15056. 10.1038/npjpcrm.2015.56

William D-C. Man, Milo A. Puhan, Samantha L. Harrison, Rachel E. Jordan, Jennifer K. Quint, Sally J. Singh. Pulmonary rehabilitation and severe exacerbations of COPD: solution or white elephant? [Invited review]. ERJ Open Research 2015; 1: 00050-2015; DOI: 10.1183/23120541.00050-2015

Jordan R, Majothi S, Heneghan NR, Blissett DB, Riley RD, Sitch AJ, Price MJ, Bates EJ, Turner AM, Bayliss S, Moore D, Singh S, Adab P, Fitzmaurice DA, Jowett S & Jolly K. Supported self-management for patients with moderate to severe chronic obstructive pulmonary disease (COPD): an evidence synthesis and economic analysis. Health Technology Assessment 2015; 19(36). 10.3310/hta19360

Majothi S, Jolly C, Heneghan NR, Price MJ, Riley RD, Turner AM, Bayliss SE, Moore DJ, Singh SJ, Adab P, Fitzmaurice DA & Jordan RE. Supported self-management for patients with COPD who have recently been discharged from hospital: a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease 2015; 10(1):853-867. 10.2147/COPD.S74162

Haroon S, Jordan RE, Takwoingi Y & Adab P. Diagnostic accuracy of screening tests for COPD: a systematic review and meta-analysis. BMJ Open 2015;5:e008133 doi:10.1136/bmjopen-2015-008133

Haroon S, Adab P, Riley RD, Marshall T, Lancashire R & Jordan RE. Predicting risk of COPD in primary care: development and validation of a clinical risk score. BMJ Open Resp Res 2015;2:e000060 doi:10.1136/bmjresp-2014-000060

Jordan R, Adab P, Jowett S, Marsh J, Riley RD, Enocson A et al. TargetCOPD : a pragmatic randomised controlled trial of targeted case finding for COPD versus routine practice in primary care : protocol. BMC Pulmonary Medicine. 2014 Oct 4;14(1). 157. Available from: 10.1186/1471-2466-14-157

Jordan RE, Adab P, Jolly K. Telemonitoring for patients with COPD [Invited editorial]. BMJ 2013;347:f5932. doi: http://dx.doi.org/10.1136/bmj.f5932

Haroon S, Adab P, Griffin C, Jordan R. Case finding for COPD in primary care: a pilot randomised controlled trial. British Journal of General Practice 2013; 63 (606): e55-e62(8)

Beattie A, Palmer K, Rees E, Riddell Z, Roberts C, Jordan R. Factors Affecting the Acceptance of Pandemic A (H1N1) Influenza Vaccine Amongst Essential Service Providers: a Cross Sectional Study. Vaccines 2013; 1 :17-31.

Lee SI, Aung EM, Chin IS, Hing J, Mummadi S, Palaniandy G, Jordan RE. Factors affecting medical students’ uptake of the 2009 pandemic influenza A (H1N1) vaccine. Influenza Research and Treatment. Volume 2012 (2012), Article ID 753164 doi:10.1155/2012/753164.

Janks M, Cooke S, Odedra A, Kang H, Bellman M, Jordan RE. Factors affecting acceptance and intention to receive pandemic influenza A H1N1 vaccine among primary school children: a cross-sectional study in Birmingham. Influenza Research & Treatment. Volume 2012 (2012), Article ID 182575

Hothersall EJ, de Bellis-Ayres S, Jordan R. Factors associated with uptake of pandemic influenza vaccine among general practitioners and practice nurses in Shropshire. Prim Care Respir J 2012;21(3):302-307. http://dx.doi.org/10.4104/pcrj.2012.00056

Haroon SMM, Adab PA, Jordan RE. Case finding for COPD in primary care: a systematic review (protocol). Prim Care Respir J 2012;21(3):354-357. DOI: http://dx.doi.org/10.4104/pcrj.2012.00060

Jordan RE, Miller MR, Lam KBH, Cheng KK, Adab P. Sex, smoking and Chronic Obstructive Pulmonary Disease. Cross sectional analysis of the Health Survey for England. Thorax 2012; doi:10.1136/thoraxjnl-2011-201384 http://thorax.bmj.com/content/67/7/600.full.pdf+html?sid=b24e18cb-9dae-48ad-958d-d9a658a69e9d

Heneghan N, Adab P, Balanos GM, Jordan RE. Manual therapy for Chronic Obstructive Pulmonary Disease: a systematic review of current evidence. Manual Therapy 2012; DOI: 10.1016/j.math.2012.05.004

Jordan RE, Cheng KK, Miller MR, Adab P. Passive smoking and chronic obstructive pulmonary disease: cross-sectional analysis of data from the Health Survey for England. BMJ Open 2011;1:e000153 doi:10.1136/bmjopen-2011-000153 http://bmjopen.bmj.com/content/1/2/e000153.full.pdf+html?sid=fc2b662f-5b4b-4682-a608-830f9ba2b193

Jordan RE, Lancashire RJ, Adab P. An evaluation of Birmingham Own Health telephone care management service among patients with poorly controlled diabetes. A retrospective comparison with the General Practice Research Database. BMC Public Health 2011, 11:707doi:10.1186/1471-2458-11-707 http://www.biomedcentral.com/1471-2458/11/707/

Jordan RE, Lam K-BH, Cheng KK, Miller MR, Marsh JL, Ayres JG, Fitzmaurice D, Adab P. Case finding for chronic obstructive pulmonary disease: a model for optimizing a targeted approach. Thorax 2010; 65: 492-8. http://thorax.bmj.com/content/65/6/492.full.pdf+html?sid=61701ba1-532c-4f9b-9205-850cd553025c

Jordan R. Hayward A. Should healthcare workers have the swine flu vaccine? [Invited editorial]. BMJ. 339:b3398, 2009. http://www.bmj.com/content/339/bmj.b3398.extract

Lam KB, Jiang CQ, Jordan RE, Miller MR, Zhang WS, Cheng KK, Lam TH, Adab P. Prior tuberculosis, smoking and airflow obstruction: A cross-sectional analysis of the Guangzhou Biobank Cohort Study. Chest 2009; 137(3): 593-600.

Lam KH, Jordan RE, Jiang CQ, Thomas GN, Miller MR, Zhang WS,LamTH, Cheng KK, Adab P. Airflow obstruction and the metabolic syndrome: the Guangzhou Biobank Cohort Study. Eur Respir J 2009, doi:10.1183/09031936.00024709

Jordan RE, Hawker JI, Ayres JG, Adab P, Tunnicliffe W, Olowokure B, Kai J, McManus RJ, Salter R, Cheng KK. The effect of social factors on winter respiratory admissions: A case-control study among older people in the UK. Br J Gen Prac 2008;58:400-402. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2419018/pdf/bjgp58-e1.pdf

Jordan RE, Hawker JI. Influenza vaccine in the over 65’s. [Invited Editorial]. BMJ 2008; 337:1183-4.

Jordan RE, Hawker JI, Ayres JG, Tunnicliffe W, Adab P, Olowokure B, et al . A case–control study of elderly patients with acute respiratory illness: Effect of influenza vaccination on admission to hospital in winter 2003–2004. Vaccine 2007; 25:7909-13.

Jordan RE, Hawker JI. Influenza in elderly people in care homes: New evidence strengthens policy to vaccinate healthcare workers [Invited Editorial]. BMJ 2006; 333:1229-30.

Burls AJ, Jordan RE, Barton P, Olowokure B,Wake B, Albon E, Hawker JI. Vaccinating healthcare workers against influenza to protect the vulnerable - is it a good use of healthcare resources? A systematic review of the evidence and an economic evaluation. Vaccine 2006; 24(19):4212-4221.

Jordan RE, Connock M, Albon E, Fry-Smith A, Olowokure B, Hawker J and Burls A. Universal vaccination of children against influenza: Are there indirect benefits to the community?: A systematic review of the evidence. Vaccine 2006; 24:1047-1062.

Jordan RE, Verlander N, Olowokure B, Hawker JI,. Age, sex, material deprivation and respiratory mortality. Respiratory Medicine 2006; 100(7):1282-1285.

Zhang D, Yin P, Freemantle N, Jordan R, Zhong N, Cheng KK . An assessment of the quality of randomised controlled trials conducted in China. Trials [Electronic Resource]. 9:22, 2008. [Impact factor 2.02]

Law MR, Morris J, Jordan RE, Wald NJ. Headaches and the treatment of blood pressure: results from a meta-analysis of 94 randomised placebo controlled trials with 24000 participants. Circulation 2005; 112: 2301 - 2306

Jordan RE, Olowokure B. Indirect community protection against influenza by vaccinating children: A review of two recent studies from Italy and the United States. Eurosurveillance Weekly 2004:8 (51): 7-9.

Law MR. Wald NJ. Morris JK. Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ. 326(7404):1427-1434, 2003 Jun 28.

Jordan R. Carter T. Cummins C. A systematic review of the utility of electrodiagnostic testing in carpal tunnel syndrome. British Journal of General Practice. 52(481):670-3, 2002 Aug.

Jordan R. Gold L. Cummins C. Hyde C. Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy. BMJ. 324(7340):757-766, 2002 Mar 30.

Stewart A. Cummins C. Gold L. Jordan R. Phillips W. The effectiveness of the levonorgestrel-releasing intrauterine system in menorrhagia: a systematic review. BJOG: an International Journal of Obstetrics & Gynaecology. 108(1):74-86, 2001 Jan.

Jordan R, Cummins C, Burls A. Laser resurfacing of the skin for the improvement of facial acne scarring: a systematic review of the evidence. British Journal of Dermatology 2000; 142: 413-423.

Jordan R, Cummins C, Burls A, Seukeran D. Laser resurfacing for facial acne scars (Cochrane Review). In: The Cochrane Library, Issue 1, 2001. Oxford:Update Software.

Branas P. Jordan R. Fry-Smith A. Burls A. Hyde C. Treatments for fatigue in multiple sclerosis: a rapid and systematic review. Health Technology Assessment (Winchester, England). 4(27):1-61, 2000.

Jordan RE, Law MR. An appraisal of the efficacy and cost effectiveness of antenatal screening for hepatitis B. Journal of Medical Screening 1997; 4(3): 117-127

Jordan R, Law M. Screening Brief: Hepatoma and chronic liver disease from maternally transmitted hepatitis B infection. Journal of Medical Screening 1998; 5: 54

Jordan RE, Smart D, Grimson P, Suman-Chauhan N, McKnight AT. Activation of the cloned human NK₃ receptor in Chinese Hamster Ovary cells characterised by the cellular acidification response using the Cytosensor microphysiometer. British Journal of Pharmacology 1998; 125: 761-766.

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