Mwayi’s research interests are mainly on economic evaluations of surgical interventions in low-and middle-income countries (LMICs). His most recent research have been focused pre-trial and preliminary economic evaluation of perioperative interventions among patients undergoing elective and emergency abdominal surgery in LMICs. As part of this work, a preliminary economic evaluation assessing the cost-effectiveness of preoperative mouthwash at reducing pneumonia was presented and the 2021 winter HESG conference and published in PLOS ONE.
Apart from research, Mwayi is also involved in building capacity among surgical staff in LMICs aimed at improving surgery resource allocation. He has been involved in training surgical staff from LMICs in basic health economics and application of the economic principles to resource allocation in surgical interventions.
Mwayi is currently providing health economics input on the planned PENGUIN trial, which aims at assessing the safety and effectiveness of perioperative interventions among abdominal surgery patients.
Mwayi is also involved in estimating the economic burden of untreated surgical conditions across the world focusing on LIMICs.