Research interests
Professor Thomas' research is at the cutting edge of understanding cardiometabolic conditions that place a significant burden on healthcare services and society as a whole. This understanding is coupled with intervention studies that inform disease prevention and patient care.
There are three main components to his research: Firstly, epidemiological studies which are designed to investigate environmental (air pollution, temperature), lifestyle (diet, physical activity, sleep) and genetic factors contributing to cardiometabolic disease (Type 2 diabetes, obesity, hypertension and dyslipidaemia) and associated morbidity and mortality, and; secondly in the treatment and prevention of these conditions, using pharmacological agents and lifestyle/behavioural modifications; thirdly better understanding and redesigning/optimising care pathways to improve patient care including with digital technologies. His contribution to the first component has resulted in greater appreciation of the pathogenesis of these diseases and has helped in development of more effective therapeutic interventions, which can be used intensively in those identified to be at greatest risk. In this manner, the application of this scientific research has been directly used to alleviate morbidity and mortality in patients with these conditions and thus provide direct benefit. Work related to the second component has led to a series of interventional studies targeting physical activity and diet and specific pharmacological agents in general populations and in specific patient groups to improve health indicators and reduce morbidity and mortality. The third package has led to service changes and is introducing/adapting digital technologies to optimise patient management.
Research themes
Ageing, Care pathways, Cardiovascular disease, Diabetes, Epidemiology, Lifestyle, Patient management, Public health.