Recent publications
Article
Wood, H, Acharjee, A, Pearce, H, Quraishi, MN, Powell, R, Rossiter, A, Beggs, A, Ewer, A, Moss, P & Toldi, G 2021, 'Breastfeeding promotes early neonatal regulatory T-cell expansion and immune tolerance of non-inherited maternal antigens', Allergy. https://doi.org/10.1111/all.14736
Crawford, H, Scerif, G, Wilde, L, Beggs, A, Stockton, J, Sandhu, P, Shelley, L, Oliver, C & McCleery, J 2021, 'Genetic modifiers in rare disorders: the case of fragile X syndrome', European Journal of Human Genetics, vol. 29, no. 1, pp. 173–183. https://doi.org/10.1038/s41431-020-00711-x
Whalley, C, Payne, K, Domingo, E, Blake, A, Richman, S, Brooks, J, Batis, N, Spruce, R, Consortium, SC, Mehanna, H, Nankivell, P & Beggs, A 2021, 'Ultra-low DNA Input into whole genome methylation assays and detection of oncogenic methylation and copy number variants in circulating tumour DNA', Epigenomes, vol. 5, no. 1, 6. https://doi.org/10.3390/epigenomes5010006
Quraishi, MN, Acharjee, A, Beggs, AD, Horniblow, R, Tselepis, C, Gkoutos, G, Ghosh, S, Rossiter, A, Loman, N, van Schaik, W, Withers, D, Walters, JRF, Hirschfield, GM & Iqbal, TH 2020, 'A pilot integrative analysis of colonic gene expression, gut microbiota, and immune infiltration in primary sclerosing cholangitis-inflammatory bowel disease: association of disease with bile acid pathways', Journal of Crohn's & Colitis, vol. 14, no. 7, pp. 935-947. https://doi.org/10.1093/ecco-jcc/jjaa021
Pestinger, V, Smith, M, Sillo, T, Findlay, JM, Laes, J-F, Martin, G, Middleton, G, Taniere, P & Beggs, AD 2020, 'Correction to: Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants', Molecular Diagnosis and Therapy, vol. 24, no. 4, pp. 505. https://doi.org/10.1007/s40291-020-00479-2
S:CORT Consortium 2020, 'Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning', Gut. https://doi.org/10.1136/gutjnl-2019-319866
Kwok, MCK, Oldreive, C, Rawstron, AC, Goel, A, Papatzikas, G, Jones, R, Drennan, S, Agathanggelou, A, Sharma-Oates, A, Evans, P, Smith, E, Dalal, S, Mao, J, Hollows, R, Gordon, N, Hamada, M, Davies, N, Parry, H, Beggs, A, Munir, T, Moreton, P, Paneesha, S, Pratt, G, Taylor, M, Forconi, F, Baird, D, Cazier, J-B, Moss, P, Hillmen, P & Stankovic, T 2020, 'Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL: natural history and mechanism of spontaneous CLL regression', Blood, vol. 135, no. 6, pp. 411-428. https://doi.org/10.1182/blood.2019001262
Schwenzer, H, Abdel Mouti, M, Neubert, P, Morris, J, Stockton, J, Bonham, S, Fellermeyer, M, Chettle, J, Fischer, R, Beggs, AD & Blagden, SP 2020, 'LARP1 isoform expression in human cancer cell lines', RNA biology. https://doi.org/10.1080/15476286.2020.1744320
OCCAMS Consortium & Beggs, A 2020, 'Machine learning to predict early recurrence after oesophageal cancer surgery', British Journal of Surgery. https://doi.org/10.1002/bjs.11461
Breeze, J, Bowley, DM, Combes, JG, Baden, J, Orr, L, Beggs, A, DuBose, J & Powers, DB 2020, 'Outcomes following penetrating neck injury during the Iraq and Afghanistan conflicts: A comparison of treatment at US and United Kingdom medical treatment facilities', The Journal of Trauma and Acute Care Surgery, vol. 88, no. 5, pp. 696-703. https://doi.org/10.1097/TA.0000000000002625
Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative 2020, 'Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial', The Lancet, vol. 395, no. 10222, pp. 417-426. https://doi.org/10.1016/S0140-6736(19)32637-6
Bosworth, A, Whalley, C, Poxon, C, Wanigasooriya, K, Pickles, O, Aldera, EL, Papakonstantinou, D, Morley, GL, Walker, EM, Zielinska, AE, McLoughlin, D, Webster, C, Plant, T, Ellis, A, Richter, A, Kidd, IM & Beggs, AD 2020, 'Rapid implementation and validation of a cold-chain free SARS-CoV-2 diagnostic testing workflow to support surge capacity', Journal of Clinical Virology, vol. 128, 104469. https://doi.org/10.1016/j.jcv.2020.104469
Stockton, JD, Nieto, T, Wroe, E, Poles, A, Inston, N, Briggs, D & Beggs, AD 2020, 'Rapid, highly accurate and cost-effective open-source simultaneous complete HLA typing and phasing of class I and II alleles using nanopore sequencing', HLA, vol. 96, no. 2, pp. 163-178. https://doi.org/10.1111/tan.13926
Review article
Tyler, R, Wanigasooriya, K, Taniere, P, Almond, M, Ford, S, Desai, A & Beggs, A 2020, 'A review of retroperitoneal liposarcoma genomics', Cancer Treatment Reviews, vol. 86, 102013. https://doi.org/10.1016/j.ctrv.2020.102013
Wanigasooriya, K, Tyler, R, Barros-Silva, JD, Sinha, Y, Ismail, T & Beggs, AD 2020, 'Radiosensitising Cancer Using Phosphatidylinositol-3-Kinase (PI3K), Protein Kinase B (AKT) or Mammalian Target of Rapamycin (mTOR) Inhibitors', Cancers, vol. 12, no. 5, 1278. https://doi.org/10.3390/cancers12051278
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