Pachnio A, Ciaurriz M, Begum J, Lal N, Zuo J, Beggs A, Moss P. Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium. PLoS Pathog. 2016 Sep 8;12(9):e1005832.
Beggs AD, Dilworth MP, Domingo E, Midgely R, Kerr D, Tomlinson IP, Middleton GW. Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer. Oncoscience. 2015 Mar 23;2(5):508-16.
Lal N, Beggs AD, Wilcox B, Middleton GW. An immunogenomic stratifier of colorectal cancer: implications for the development of targeted immunotherapy. Oncoimmunology 4:3, e976052 DOI: 10.4161/ 2162402X.2014.976052
Mussai F, Egan S, Higginbotham-Jones J, Perry T, Beggs A, Odintsova E, Loke J, Pratt G, U KP, Lo A, Ng M, Kearns P, Cheng P, De Santo C. Blood. 2015 Feb 20. pii: blood-2014-09-600643.
Beggs AD, Dilworth MP. Surgery in the era of the ‘omics revolution. Br J Surg. 2015 Jan;102(2):e29-40.
Leong KJ, Beggs A, James J, Morton DG, Matthews GM, Bach SP. Biomarker-based treatment selection in early-stage rectal cancer to promote organ preservation. Br J Surg. 2014 Sep;101(10):1299-309.
Beggs AD, Jones A, Shepherd N, Arnaout A, Finlayson C, Abulafi AM, Morton DG, Matthews GM, Hodgson SV, Tomlinson IP. Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation. PLoS Genet. 2013 May;9(5):e1003488.
Beggs AD, Domingo E, Abulafi M, Hodgson SV, Tomlinson IP. A study of genomic instability in early preneoplastic colonic lesions. Oncogene Dec 2012. doi: 10.1038/ onc.2012.584.
Beggs AD, Domingo E, McGregor M, Presz M, Johnstone E, Midgley R, Kerr D, Oukrif D, Novelli M, Abulafi M, Hodgson SV, Fadhil W, Ilyas M, Tomlinson IP. Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN. Oncotarget, 3(10).
Beggs AD, Jones A, El-Bahwary M, Abulafi M, Hodgson SV, Tomlinson IP. Whole-genome methylation analysis of benign and malignant colorectal tumours. J Pathol. 2012 Oct 24. doi: 10.1002/path.4132.
Jones AM, Beggs AD, Carvajal-Carmona L, Walker M, Howarth K, Farrington S, Campbell H, Zauber A, Bertagnolli M, Kerr D, Hodgson SV, Dunlop M, Tomlinson I. Longer telomeres and TERC polymorphisms are associated with an increased risk of colorectal carcinoma and adenoma. Gut. 2012 Feb;61(2):248-54.
Beggs AD, Hodgson SV et al. Peutz-Jeghers Syndrome: Systematic review and management recommendations. Gut 2010;59:975-986
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