Sanchez-Bailon M-P, ChoiS-Y, Dufficy E.R, SharmaK, McNee G.S, Gunnel E, ChiangK, Sahay D, MaslenS, Stewart G.S, Skehel J.M, Dreveny I and Davies C.C (2021). Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair. Nat. Commun. 12, 6313.
Gunnell EA, Al-Noori A, Muhsen U, Davies CC, Dowden J, Dreveny I (2020). Structural and Biochemical Evaluation of Bisubstrate Inhibitors of Protein Arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Biochem J 28;477(4):787-800. doi: 10.1042/BCJ20190826.
Jarrold J and Davies C.C., (2019). PRMTs and arginine methylation: Cancer’s best kept secret? Trends Mol. Med. S1471-4914 (19) 30124-8
Chiang K and Davies CC (2018). Linking PRMT5 to breast cancer stem cells: New therapeutic opportunities? Mol Cell Oncol 5 (3):e1441628
Chiang K, Zielinska AE, Shaaban AM, Sanchez-Bailon MP, Jarrold J, Clarke TL, Zhang J, Francis A, Jones LJ, Smith S, Barbash O, Guccione E, Farnie G, Smalley MJ, Davies CC (2017). PRMT5 is a critical regulator of breast cancer stem cells via histone methylation and FOXP1 expression. Cell Rep. 21(12):3498-3513.
Clarke TL, Sanchez-Bailon MP, Chiang K, Reynolds JJ, Herrero-Ruiz J, Bandeiras TM, Matias PM, Maslen SL, Skehel JM, Stewart GS, Davies CC (2017). PRMT5-dependent methylation of the TIP60 coactivator RUVBL1 is a key regulator of homologous recombination. Molecular Cell. 65(5):900-916.e7.
McNee G, Eales KL, Wei W, Williams DS, Barkhuizen A, Bartlett DB, Essex S, Anandram S, Filer A, Moss PA, Pratt G, Basu S, Davies CC, Tennant DA (2017). Citruillination of Histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma. Leukemia;31(2):373-381
Carneiro DG, Clarke T, Davies CC, Bailey D (2016). Identifying novel protein interactions: Proteomic methods, optimisation approaches and data analysis pipelines. Methods. 15;95:46-54. doi: 10.1016/j.ymeth.2015.08.022.
Davies CC, Harvey E, McMahon R, Finegan KG, Connor F, Davies RJ, Tuveson DA, Tournier C (2014) Conditional deletion of mkk4 and mkk7 cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma in mice. Cancer Research 74 (12), 3344-56.
Davies CC and Behrens A (2013) Arginine methylation: Making its mark on AP-1 gene activation. Cell Cycle 12:15, 2333–2334.
Davies CC, Chakraborty A, Diefenbacher ME, Skehel M, and Behrens A (2013) Arginine methylation of the c-Jun co-activator RACO-1 is required for c-Jun/AP-1 activation. The EMBO Journal 32, 1556 – 1567.
Davies C and Tournier C (2012). Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological processes to design novel therapeutic stratagies. Biochem Soc Trans. (40):85-9.
Davies CC, Chakraborty A, Cipriani F, Haigh K, Haigh JJ and Behrens A (2010). RACO-1 links AP-1 activity to growth
factor signalling. Nature Cell Biology, (10): 963-72 *Signalling Gatway Featured Article of the Week
Davies CC, Mak TW, Young LS, Eliopoulos AG (2005). TRAF6 is required for TRAF2 dependent CD40 signal
transduction in nonhemopoietic cells. Mol. Cell Biol. (25): 9806-19
Davies CC, Bem D, Young LS, Eliopoulos AG (2005). NF-kB overrides the apoptotic program of TNF receptor 1 but
not CD40 in carcinoma cells. Cell Signal (17): 723-38
Davies CC, Mason J, Wakelam MJ, Young LS, Eliopoulos AG (2004). Inhibition of PI3K and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells. J Biol Chem. (279): 1010-19
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