Dr Rebecca Jones PhD

Dr Rebecca Jones

Institute of Cancer and Genomic Sciences
Senior Research Fellow

Contact details

Address
Institute of Biomedical Research West
Institute of Cancer and Genomic Sciences
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Rebecca Jones is a Senior Research Fellow in the Institute of Cancer and Genomic Sciences.

Qualifications

  • Associate Fellow of the HEA 2018
  • PhD in Biochemistry, 2010

Teaching

Research

Publications

Jones, R.M., Priego Moreno, S., Gambus, A. (2019). DNA Replication Termination and Genomic Instability in ‘DNA Repair and Replication: Mechanisms and Clinical Significance’. (Grand, R.J.A and Reynolds, J.J., editors). pp 21-35. CRC Press, Boca Raton, FL.

Priego Moreno, S., Jones, R.M., Gambus, A. (2019). DNA Replication and Cell Cycle Control in ‘DNA Repair and Replication: Mechanisms and Clinical Significance’. (Grand, R.J.A and Reynolds, J.J., editors). pp 5-20. CRC Press, Boca Raton, FL.

Priego Moreno, S., Jones, R.M., Poovathumkadavil, D., Gambus, A. (2018). Mitotic replisome disassembly in vertebrates. BioRxiv doi: http://dx.doi.org/10.1101/418368.

Kotsantis, P., Marques Silva, L., Irmscher, S., Jones, R.M., Folkes, L., Gromak, N., Petermann, E. (2016). Increased global transcription activity as a mechanism of replications stress in cancer. Nat. Commun. 7: 13087.

Jones, R.M.,Kotsantis, P., Stewart, G.S., Groth, P., Petermann, E. (2014). BRCA2 and RAD51 promote double-strand break formation and cell death in response to Gemcitabine. Mol. Cancer Ther. 13 (10): 2412-21.

Kotsantis, P., Jones, R.M., Higgs, M.R., Petermann, E. (2014). Cancer therapy and replication stress: forks on the road to perdition. Adv. Clin. Chem. 69: 91-138. 

Jones, R.M., Mortusewicz, O., Afzal, I., Lorvellec, M., Garcia, P., Helleday, T., Petermann, E. (2013). Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress. Oncogene 32: 3744-53.

Feigenbutz, M., Jones, R., Besong, T.M., Harding, S.E., Mitchell, P. 2013. Assembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47. J. Biol. Chem. 288: 15959-70.

Zimmerman, K.M., Jones, R.M., Petermann, E., Jeggo, P.A. 2013. Diminished origin licensing capacity specifically sensitises tumour cells to replication stress. Mol. Cancer Res. 11: 370-80.

Jones, R.M., Petermann, E. (2012). Replication fork dynamics and the DNA damage response. Biochem. J. 443: 13-26.

Costello, J.L., Stead, J.A., Feigenbutz, M., Jones, R.M., Mitchell, P. 2011. The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3’-maturation. J. Biol. Chem. 286: 4535-4543.

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