Piberger, L, Bowry, A, Kelly, R, Walker, A, Gonzalez-Acosta, D, Bailey, L, Doherty, A, Mendez, J, Morris, J, Bryant, HE & Petermann, E 2020, 'PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts', Nature Communications. <https://nature-research-under-consideration.nature.com/posts/60731-primpol-dependent-single-stranded-gap-formation-mediates-homologous-recombination-at-bulky-dna-adducts>
Bowry, A, Piberger, AL, Rojas, P, Saponaro, M & Petermann, E 2018, 'BET inhibition induces HEXIM1- and RAD51-dependent conflicts between transcription and replication', Cell Reports, vol. 25, no. 8, pp. 2061–2069. https://doi.org/10.1016/j.celrep.2018.10.079
Kotsantis, P, Marques Silva, L, Irmscher, S, Jones, R, Folkes, L, Gromak, N & Petermann, E 2016, 'Increased global transcription activity as a mechanism of replication stress in cancer', Nature Communications, vol. 7, 13087. https://doi.org/10.1038/ncomms13087
Jones, R, Kotsantis, P, Stewart, G, Groth, P & Petermann, E 2014, 'BRCA2 and RAD51 promote double-strand break formation and cell death in response to Gemcitabine', Molecular Cancer Therapeutics, vol. 13, no. 10, pp. 2412-2421. https://doi.org/10.1158/1535-7163.MCT-13-0862
Jones, R, Mortusewicz, O, Afzal, I, Lorvellec, M, García, P, Helleday, T & Petermann, E 2012, 'Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress', Oncogene. https://doi.org/10.1038/onc.2012.387
Nazeer, R, Qashqari, F, Albalawi, A, Piberger, AL, Tilotta, M, Read, M, Hu, S, Davis, S, McCabe, C, Petermann, E & Turnell, A 2019, 'Adenovirus E1B 55-kilodalton protein targets SMARCAL1 for degradation during infection and modulates cellular DNA replication', Journal of virology, vol. 93, no. 13, e00402-19. https://doi.org/10.1128/JVI.00402-19
Benedict, B, van Harn, T, Dekker, M, Hermsen, S, Kucukosmanoglu, A, Pieters, W, Delzenne-Goette, E, C Dorsman, J, Petermann, E, Foijer, F & te Riele, H 2018, 'Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells', Elife, vol. 7, e37868. https://doi.org/10.7554/eLife.37868
Bayley, R, Blakemore, D, Cancian, L, Dumon, S, Volpe, G, Ward, C, Al Maghrabi, R, Gujar, J, Reeve, N, Raghavan, M, Higgs, M, Stewart, G, Petermann, E & Garcia, P 2018, 'MYBL2 supports DNA double strand break repair in haematopoietic stem cells', Cancer Research, vol. 78, no. 20, pp. 5767-5779. https://doi.org/10.1158/0008-5472.CAN-18-0273
Ronson, G, Piberger, AL, Higgs, M, Olsen, A, Stewart, G, McHugh, P, Petermann, E & Lakin, N 2018, 'PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation', Nature Communications, vol. 9, 746. https://doi.org/10.1038/s41467-018-03159-2
Kwok, M, Davies, N, Agathanggelou, A, Smith, E, Oldreive, C, Petermann, E, Stewart, G, Brown, J, Lau, A, Pratt, G, Parry, H, Taylor, M, Moss, P, Hillmen, P & Stankovic, T 2016, 'ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53 or ATM defective chronic lymphocytic leukemia cells', Blood, vol. 127, no. 5, pp. 582-595. https://doi.org/10.1182/blood-2015-05-644872
Kotsantis, P, Jones, R, Higgs, M & Petermann, E 2015, Cancer Therapy and Replication Stress: Forks on the Road to Perdition. in GS Makowski (ed.), Advances in Clinical Chemistry. vol. 69, Academic Press (Elsevier), pp. 91-138. <http://www.sciencedirect.com/science/article/pii/S0065242314000420>
Petermann, E 2018, Homologous Recombination at Replication Forks. in R Grand & J Reynolds (eds), DNA Repair and Replication: Mechanisms and Clinical Significance. Routledge.
Kwok, M, Davies, N, Agathanggelou, A, Smith, E, Petermann, E, Yates, E, Brown, J, Lau, A & Stankovic, T 2015, 'Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway', The Lancet, vol. 385 Suppl 1, pp. S58. https://doi.org/10.1016/S0140-6736(15)60373-7
Bowry, A, Piberger, AL & Petermann, E 2018, 'BET inhibition induces transcription-replication conflicts that depend on HEXIM1 and RAD51', RNA and genome maintenance, Mainz, Germany, 10/10/18 - 13/10/18.
Piberger, AL & Petermann, E 2018, 'Mechanisms of Benzo[a]pyrene-induced recombination', 42nd Annual Meeting of the United Kingdom Environmental Mutagen Society (UKEMS), Oxford, United Kingdom, 2/09/18 - 5/09/18.
Tang, HM, Kotsantis, P, Gromak, N & Petermann, E 2018, 'RNA/DNA hybrid metabolism and replication stress in cancer', RNA and genome maintenance, Mainz, Germany, 10/10/18 - 13/10/18.
Kotsantis, P, Marques Silva, L, Irmscher, S, Jones, R, Folkes, L, Gromak, N & Petermann, E 2017, 'Increased global transcription activity as a mechanism of oncogene-induced replication stress', 2nd DNA Replication as a Source of DNA Damage Conference, Rome, Italy, 3/07/17 - 6/07/17.
Kotsantis, P, Marques Silva, L, Irmscher, S, Jones, R, Folkes, L, Gromak, N & Petermann, E 2016, 'Increased global transcription activity as a mechanism of replication stress in cancer', Mutagenesis Gordon Research Conference, Girona, Spain, 5/06/16 - 10/06/16.
Kotsantis, P, Irmscher, S, Jones, R, Gromak, N & Petermann, E 2015, 'Oncogenic RAS causes replication stress by deregulating transcription', Keystone Symposium DNA Replication and Recombination, Whistler, Canada, 1/03/15 - 6/03/15.
Kotsantis, P, Petermann, E & Boulton, SJ 2018, 'Mechanisms of oncogene-induced replication stress: jigsaw falling into place', Cancer Discovery, vol. 8, no. 5, pp. 537-555. https://doi.org/10.1158/2159-8290.CD-17-1461
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