Sagar N Doshi BSc(Hons) MBChB FRCP MD

Sagar N Doshi

Institute of Cardiovascular Sciences
Honorary Associate Clinical Professor
TAVI Program Director, Consultant Cardiologist & Senior Lecturer

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Sagar N Doshi is an Honorary Associate Clinical Professor at the University of Birmingham, an Interventional Cardiologist and Director of the Transcatheter Aortic Valve Implantation (TAVI) programme at the Queen Elizabeth Hospital Birmingham.

He has a national and international reputation in the field of transcatheter heart interventions and has led the TAVI program at QEHB since its inception in 2008. He was awarded a BHF Junior Research Fellowship in 1999 and undertook a prestigious Interventional Training Fellowship at Mount Sinai Hospital New York, USA, in 2001. His research interests include structural heart interventions, advanced coronary heart disease interventions, haemodynamic support devices and vascular biology with the aim of improving clinical outcomes and technique.

He has regularly lectured nationally and internationally and has a keen interest in post-graduate education. He has run post-graduate courses in rotational atherectomy, intravascular ultrasound, percutaneous left ventricular support devices, trans-septal puncture and trans-axillary TAVI. He is a proctor for a number of biomedical companies and has regularly trained physicians in the United States, Japan and Europe.

He has published in widely in leading cardiology journals including Circulation, Arteriosclerosis Thrombosis and Vascular Biology, Journal of the American College of Cardiology, European Heart Journal, Heart and Eurointervention.

Qualifications

  • FRCP 2011 (Royal College of Physicians, London)
  • MD 2003 (Wales Heart Research Institute)
  • MBChB 1990 (University of Wales)
  • BSc(Hons) 1987 (University of Wales)

Biography

Sagar N Doshi graduated in 1990 from the University of Wales gaining a number of undergraduate prizes and distinctions. He undertook an intercalated BSc(Hons) in anatomy. He commenced his cardiology training on the West Midlands Cardiology rotation in 1994. In 1999 he was awarded a British Heart Foundation Junior research Fellowship and undertook a 2-year period of research at the Wales Heart Research Institute gaining an MD in 2003. His field of research was homocysteine and endothelial dysfunction. In 2001 he was awarded an Interventional Fellowship at Mount Sinai Hospital New York where he trained in complex coronary, structural and peripheral interventions. He completed his cardiology training on the West Midlands rotation and was appointed as a Consultant Interventional Cardiologist at Queen Elizabeth Hospital in 2005. He established the TAVI programme in 2008 and has overseen the continuous expansion of the program. His work focuses mainly on structural heart interventions including mitral and tricuspid Transcatheter Edge to Edge (TEER), balloon mitral valvuloplasty and paravalvular leak closure.

Teaching

  • Clinical tutor for 4th year medical students at University of Birmingham
  • Postgraduate courses - transseptal puncture, percutaneous transaxillary TAVI

Research

  • Transcatheter Aortic Valve Intervention
  • Mitral Valve Disease and interventions
  • Tricuspid Valve Disease and interventions
  • Percutaneous left ventricular assist devices

Research Groups and Centres

Sagar Navin Doshi on ResearchGate

Other activities

Publications

Ali M, Hildick-Smith D, Parker J, Malkin CJ, Cunnington MS, Gurung s, Mailey J, MacCarthy PA, Bharucha A,. Brecker SJ, Hoole SP, Dorman A, Doshi SN, Wiper A, Buch M, Banning AP, Spence M, Blackman DJ.  Long‐term durability of self‐expanding and balloon‐expandable transcatheter aortic valve prostheses: UK TAVI registry. Catheter Cardiovasc Interv March 2023 https://doi.org/10.1002/ccd.30627

Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial. Lancet 2022 Oct 8;400(10359):1195-1205.

Doshi SN, Savvoulidis P, Mechery A, Lawton E, Ludman PF, Nadir A. A Modified Buddy-Wire Technique for Crossing of the Interatrial Septum With the Sapien 3 Valve During Transseptal Mitral Valve-in-Valve/Ring Procedures. CJC Open. 2022 Oct; 4(10): 886–893

Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial. May 2022. JAMA The Journal of the American Medical Association 327(19):1875

Savvoulidis P, Moody WE, Steeds R, Ludman PF, Bradley JR, Singh A, Lawton E, Nadir A, and Sagar N. Doshi. A time-efficient protocol for transthoracic echocardiography during transfemoral transcatheter aortic valve implantation: early identification and effective management of intraprocedural complications. Echo Res Pract. 2022; 9: 3.

Savvoulidis P, Mechery A , Lawton E, Ludman PF , Sharma H , Thompson S , Khalil A , Kalogeropoulos A , Khan SQ , Nadir A  and Sagar N Doshi. Comparison of left ventricular with right ventricular rapid pacing on tamponade during TAVI. Int J Cardiol. 2022 Aug 1;360:46-52.

Umar H, Sharma H, Osheiba M, Roy A, Ludman PF, Townend JN, Nadir A, Doshi SN, George S, Zaphiriou A, Khan SQ. Changing trends in the incidence, management and outcomes of coronary artery perforation over an 11-year period: single-centre experience. Open Heart. 2022; 9(1): e001916.

Sharma H, Yuan M, Shakeel I, Hodson J, Radhakrishnan A, Brown S, May J, O’Connor K, Zia N, Doshi SN, Townend JN, Myerson SG, Ludman PF, Steeds RP, Nadir A. A Longitudinal Study of Mitral Regurgitation Detected after Acute Myocardial Infarction. J Clin Med. 2022 Feb; 11(4): 965

Patterson T, Clayton T, Dodd M, Khawaja Z, Morice MC, Wilson K,  Kim WK,  Meneveau N, Hambrecht R, Byrne J, Carrié D, Fraser D, Roberts DH, Doshi SN, Zaman A, Banning AP, Eltchaninoff H, Le Breton H, Smith D, Cox I, Frank D, Gershlick A, de Belder M, Thomas M, Hildick-Smith D, Prendergast B, Redwood S. ACTIVATION Trial Investigators. ACTIVATION (PercutAneous CoronaryinTervention prIor to transcatheter aortic VAlve implantaTION). JACC Cardiovasc Interv. 2021 Sep 27;14(18):1965-1974

Saia F, Gandolfo C, Palmerini T, Berti S, Doshi SN, Laine M, Marcelli C, Piva T, Ribichini F, De Benedictis M, Cardaioli F, Cannata S, Tarantini G. In-hospital and thirty-day outcomes of the SAPIEN 3 Ultra balloon-expandable transcatheter aortic valve: the S3U registry. EuroIntervention. 2020 Feb 20;15(14):1240-1247. doi: 10.4244/EIJ-D-19-00541.