Recent publications
Article
Hall, C, Law, JP, Reyat, JS, Cumberland, MJ, Hang, S, Vo, NTN, Raniga, K, Weston, CJ, O’Shea, C, Townend, JN, Gehmlich, K, Ferro, CJ, Denning, C & Pavlovic, D 2023, 'Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype', Scientific Reports, vol. 13, no. 1, 12137. https://doi.org/10.1038/s41598-023-39369-y
Broadway-Stringer, S, Jiang, H, Wadmore, K, Hooper, C, Douglas, G, Steeples, V, Azad, AJ, Singer, E, Reyat, JS, Galatik, F, Ehler, E, Bennett, P, Kalisch-Smith, JI, Sparrow, DB, Davies, B, Djinovic-Carugo, K, Gautel, M, Watkins, H & Gehmlich, K 2023, 'Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2', Cells, vol. 12, no. 5, 721. https://doi.org/10.3390/cells12050721
McColgan, G, Villarroel, M & Gehmlich, K 2023, 'Should young athletes be screened for cardiomyopathies to reduce the burden of sudden cardiac death in athletes?', Biophysical Reviews, vol. 15, no. 3, pp. 321-327. https://doi.org/10.1007/s12551-023-01085-2
Cumberland, M, Riebel, LL, Roy, A, O'Shea, C, Holmes, A, Denning, C, Kirchhof, P, Rodriguez, B & Gehmlich, K 2022, 'Basic Research Approaches to Evaluate Cardiac Arrhythmia in Heart Failure and Beyond', Frontiers in Physiology, vol. 13, 806366. https://doi.org/10.3389/fphys.2022.806366
O'Reilly, M, Sommerfeld, LC, O'Shea, C, Broadway-Stringer, S, Andaleeb, S, Reyat, JS, Kabir, SN, Stastny, D, Malinova, A, Delbue, D, Fortmueller, L, Gehmlich, K, Pavlovic, D, Skryabin, BV, Holmes, AP, Kirchhof, P & Fabritz, L 2022, 'Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide', EP Europace. https://doi.org/10.1093/europace/euac218
Hall, C, Gehmlich, K, Denning, C & Pavlovic, D 2021, 'Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease', Journal of the American Heart Association, vol. 10, no. 5, e019338. https://doi.org/10.1161/JAHA.120.019338
Jiang, H, Hooper, C, Kelly, M, Steeples, V, Simon, J, Beglov, J, Azad, A, Leinhos, L, Bennett, P, Ehler, E, Kalisch-Smith, J, Sparrow, D, Fischer, R, Heilig, R, Isackson, H, Ehsan, M, Patone, G, Huebner, N, Davies, B, Watkins, H & Gehmlich, K 2021, 'Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant', Basic research in cardiology, vol. 116, no. 1, 14, pp. 14. https://doi.org/10.1007/s00395-021-00853-z
Collier, MP, Alderson, TR, de Villiers, CP, Nicholls, D, Gastall, HY, Allison, TM, Degiacomi, MT, Jiang, H, Mlynek, G, Furst, DO, van der Ven, PFM, Djinovic-Carugo, K, Baldwin, AJ, Watkins, H, Gehmlich, K & Benesch, JLP 2019, 'HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C', Science Advances, vol. 5, no. 5, eaav8421. https://doi.org/10.1126/sciadv.aav8421
Azad, A, Poloni, G, Sontayananon, N, Jiang, H & Gehmlich, K 2019, 'The giant titin: how to evaluate its role in cardiomyopathies', Journal of Muscle Research and Cell Motility, vol. 40, no. 2, pp. 159-167. https://doi.org/10.1007/s10974-019-09518-w
Review article
Noureddine, M & Gehmlich, K 2023, 'Structural and signaling proteins in the Z-disk and their role in cardiomyopathies', Frontiers in Physiology, vol. 14, 1143858. https://doi.org/10.3389/fphys.2023.1143858
Patel, L, Worch, JC, Dove, AP & Gehmlich, K 2023, 'The Utilisation of Hydrogels for iPSC-Cardiomyocyte Research', International Journal of Molecular Sciences, vol. 24, no. 12, 9995. https://doi.org/10.3390/ijms24129995
Wadmore, K, Azad, A & Gehmlich, K 2021, 'The role of Z-disc proteins in myopathy and cardiomyopathy', International Journal of Molecular Sciences, vol. 22, no. 6, 3058, pp. 1-30. https://doi.org/10.3390/ijms22063058
Sontayananon, N, Redwood, C, Davies, B & Gehmlich, K 2020, 'Fluorescent PSC-derived cardiomyocyte reporter lines: generation approaches and their applications in cardiovascular medicine', Biology, vol. 9, no. 11, 402, pp. 1-24. https://doi.org/10.3390/biology9110402
Boycott, H, Nguyen, M, Vrellaku, B, Gehmlich, K & Robinson, P 2020, 'Nitric oxide and mechano-electrical transduction in cardiomyocytes', Frontiers in Physiology, vol. 11, 606740. https://doi.org/10.3389/fphys.2020.606740
Vimalanathan, AK, Ehler, E & Gehmlich, K 2018, 'Genetics of and pathogenic mechanisms in arrhythmogenic right ventricular cardiomyopathy', Biophysical Reviews, vol. 10, no. 4, pp. 973-982. https://doi.org/10.1007/s12551-018-0437-0
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