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Damaskinaki, F-N, Jooss, NJ, Martin, EM, Clark, JC, Thomas, MR, Poulter, NS, Emsley, J, Kellam, B, Watson, SP & Slater, A 2023, 'Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization', Journal of thrombosis and haemostasis : JTH, vol. 21, no. 2, pp. 317-328. https://doi.org/10.1016/j.jtha.2022.11.002
Jooss, NJ, Smith, CW, Pike, JA, Farndale, RW, Henskens, YMC, Watson, SP, Heemskerk, JWM & Poulter, NS 2023, 'Platelet glycoprotein VI cluster size is related to thrombus formation and phosphatidylserine exposure in collagen-adherent platelets under arterial shear', Journal of thrombosis and haemostasis : JTH, vol. 21, no. 8, pp. 2260-2267. https://doi.org/10.1016/j.jtha.2023.04.028
Jooss, NJ, Smith, CW, Slater, A, Montague, SJ, Di, Y, O'shea, C, Thomas, MR, Henskens, YMC, Heemskerk, JWM, Watson, SP & Poulter, NS 2022, 'Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling and thrombus formation', Journal of Thrombosis and Haemostasis, vol. 20, no. 11, pp. 2617-2631. https://doi.org/10.1111/jth.15836
Bourne, J, Smith, C, Jooss, N, Di, Y, Brown, H, Montague, S, Thomas, M, Poulter, N, Rayes, J & Watson, SP 2022, 'CLEC-2 supports platelet aggregation in mouse but not human blood at arterial shear', Thrombosis and Haemostasis, vol. 122, no. 12, pp. 1988-2000. https://doi.org/10.1055/a-1896-6992
Maqsood, Z, Clark, JC, Martin, EM, Cheung, YFH, Morán, LA, Watson, SET, Pike, JA, Di, Y, Poulter, NS, Slater, A, Lange, BMH, Nieswandt, B, Eble, JA, Tomlinson, MG, Owen, DM, Stegner, D, Bridge, LJ, Wierling, C & Watson, SP 2022, 'Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins', PLoS Computational Biology, vol. 18, no. 11, e1010708. https://doi.org/10.1371/journal.pcbi.1010708
Neagoe, RAI, Gardiner, EE, Stegner, D, Nieswandt, B, Watson, S & Poulter, N 2022, 'Rac inhibition causes impaired GPVI signalling in human platelets through GPVI shedding and reduction of PLCγ2 phosphorylation', International Journal of Molecular Sciences, vol. 23, no. 7, 3746. https://doi.org/10.3390/ijms23073746
Colicchia, M, Schrottmaier, WC, Perrella, G, Reyat, JS, Begum, J, Slater, A, Price, J, Clark, JC, Zhi, Z, Simpson, M, Bourne, J, Poulter, NS, Khan, AO, Nicolson, PLR, Pugh, MR, Harrison, P, Iqbal, AJ, Rainger, GE, Watson, SP, Thomas, MR, Mutch, NJ, Assinger, A & Rayes, J 2022, 'S100A8/A9 drives the formation of procoagulant platelets through GPIbα', Blood. https://doi.org/10.1182/blood.2021014966
Smith, C, Harbi, M, Garcia Quintanilla, L, Rookes, K, Brown, H, Poulter, N, Watson, S, Nicolson, P & Thomas, MR 2022, 'The Btk inhibitor AB-95-LH34 potently inhibits atherosclerotic plaque-induced thrombus formation and platelet procoagulant activity', Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15899
Koo, CZ, Matthews, AL, Harrison, N, Szyroka, J, Nieswandt, B, Gardiner, E, Poulter, NS & Tomlinson, MG 2022, 'The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors', International Journal of Molecular Sciences, vol. 23, no. 5, 2440. https://doi.org/10.3390/ijms23052440
Jooss, N & Poulter, N 2021, 'A large-scale histological investigation gives insight into the structure of ischemic stroke thrombi', Platelets, vol. 32, no. 2, pp. 147-150. https://doi.org/10.1080/09537104.2020.1869713
Pike, J, Simms, V, Smith, C, Morgan, N, Khan, A, Poulter, N, Styles, I & Thomas, S 2021, 'An adaptable analysis workflow for characterization of platelet spreading and morphology', Platelets, vol. 32, no. 1, pp. 54-58. https://doi.org/10.1080/09537104.2020.1748588
Clark, J, Neagoe, RAI, Zuidscherwoude, M, Kavanagh, D, Slater, A, Martin, E, Soave, M, Stegner, D, Nieswandt, B, Poulter, N, Hummert, J, Herten, D-P, Tomlinson, M, Hill, SJ & Watson, S 2021, 'Evidence that GPVI is expressed as a mixture of monomers and dimers, and that the D2 domain is not essential for GPVI activation: GPVI dimerisation is not critical for ligand binding', Thrombosis and Haemostasis, vol. 2021, no. 00, pp. 1-26. https://doi.org/10.1055/a-1401-5014
Zhi, Z, Jooss, NJ, Sun, Y, Colicchia, M, Slater, A, Moran, LA, Cheung, HYF, Di, Y, Rayes, J, Poulter, NS, Watson, SP & Iqbal, AJ 2021, 'Galectin-9 activates platelet ITAM receptors glycoprotein VI and C-type lectin-like receptor-2', Journal of thrombosis and haemostasis : JTH. https://doi.org/10.1111/jth.15625
Pallini, C, Pike, J, O'Shea, C, Andrews, R, Gardiner, EE, Watson, S & Poulter, N 2021, 'Immobilised collagen prevents shedding and induces sustained GPVI clustering and signalling in platelets', Platelets, vol. 32, no. 1, pp. 59-73. https://doi.org/10.1080/09537104.2020.1849607
Nicolson, P, Nock, SH, Hinds, J, Garcia Quintanilla, L, Smith, C, Campos, J, Brill, A, Pike, J, Khan, A, Poulter, N, Kavanagh, D, Watson, S, Watson, CN, Clifford, H, Huissoon, A, Pollitt, A, Eble, JA, Pratt, D, Watson, S & Hughes, C 2021, 'Low-dose Btk inhibitors selectively block platelet activation by CLEC-2', Haematologica, vol. 106, no. 1, pp. 208-219. https://doi.org/10.3324/haematol.2019.218545
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