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Jooss, NJ, Smith, CW, Slater, A, Montague, SJ, Di, Y, O'shea, C, Thomas, MR, Henskens, YMC, Heemskerk, JWM, Watson, SP & Poulter, NS 2022, 'Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling and thrombus formation', Journal of Thrombosis and Haemostasis, vol. 20, no. 11, pp. 2617-2631. https://doi.org/10.1111/jth.15836
Maqsood, Z, Clark, JC, Martin, EM, Cheung, YFH, Morán, LA, Watson, SET, Pike, JA, Di, Y, Poulter, NS, Slater, A, Lange, BMH, Nieswandt, B, Eble, JA, Tomlinson, MG, Owen, DM, Stegner, D, Bridge, LJ, Wierling, C & Watson, SP 2022, 'Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins', PLoS Computational Biology, vol. 18, no. 11, e1010708. https://doi.org/10.1371/journal.pcbi.1010708
Neagoe, RAI, Gardiner, EE, Stegner, D, Nieswandt, B, Watson, S & Poulter, N 2022, 'Rac inhibition causes impaired GPVI signalling in human platelets through GPVI shedding and reduction of PLCγ2 phosphorylation', International Journal of Molecular Sciences, vol. 23, no. 7, 3746. https://doi.org/10.3390/ijms23073746
Colicchia, M, Schrottmaier, WC, Perrella, G, Reyat, JS, Begum, J, Slater, A, Price, J, Clark, JC, Zhi, Z, Simpson, M, Bourne, J, Poulter, NS, Khan, AO, Nicolson, PLR, Pugh, MR, Harrison, P, Iqbal, AJ, Rainger, GE, Watson, SP, Thomas, MR, Mutch, NJ, Assinger, A & Rayes, J 2022, 'S100A8/A9 drives the formation of procoagulant platelets through GPIbα', Blood. https://doi.org/10.1182/blood.2021014966
Smith, C, Harbi, M, Garcia Quintanilla, L, Rookes, K, Brown, H, Poulter, N, Watson, S, Nicolson, P & Thomas, MR 2022, 'The Btk inhibitor AB-95-LH34 potently inhibits atherosclerotic plaque-induced thrombus formation and platelet procoagulant activity', Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15899
Koo, CZ, Matthews, AL, Harrison, N, Szyroka, J, Nieswandt, B, Gardiner, E, Poulter, NS & Tomlinson, MG 2022, 'The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors', International Journal of Molecular Sciences, vol. 23, no. 5, 2440. https://doi.org/10.3390/ijms23052440
Jooss, N & Poulter, N 2021, 'A large-scale histological investigation gives insight into the structure of ischemic stroke thrombi', Platelets, vol. 32, no. 2, pp. 147-150. https://doi.org/10.1080/09537104.2020.1869713
Pike, J, Simms, V, Smith, C, Morgan, N, Khan, A, Poulter, N, Styles, I & Thomas, S 2021, 'An adaptable analysis workflow for characterization of platelet spreading and morphology', Platelets, vol. 32, no. 1, pp. 54-58. https://doi.org/10.1080/09537104.2020.1748588
Clark, J, Neagoe, RAI, Zuidscherwoude, M, Kavanagh, D, Slater, A, Martin, E, Soave, M, Stegner, D, Nieswandt, B, Poulter, N, Hummert, J, Herten, D-P, Tomlinson, M, Hill, SJ & Watson, S 2021, 'Evidence that GPVI is expressed as a mixture of monomers and dimers, and that the D2 domain is not essential for GPVI activation: GPVI dimerisation is not critical for ligand binding', Thrombosis and Haemostasis, vol. 2021, no. 00, pp. 1-26. https://doi.org/10.1055/a-1401-5014
Zhi, Z, Jooss, NJ, Sun, Y, Colicchia, M, Slater, A, Moran, LA, Cheung, HYF, Di, Y, Rayes, J, Poulter, NS, Watson, SP & Iqbal, AJ 2021, 'Galectin-9 activates platelet ITAM receptors glycoprotein VI and C-type lectin-like receptor-2', Journal of thrombosis and haemostasis : JTH. https://doi.org/10.1111/jth.15625
Pallini, C, Pike, J, O'Shea, C, Andrews, R, Gardiner, EE, Watson, S & Poulter, N 2021, 'Immobilised collagen prevents shedding and induces sustained GPVI clustering and signalling in platelets', Platelets, vol. 32, no. 1, pp. 59-73. https://doi.org/10.1080/09537104.2020.1849607
Nicolson, P, Nock, SH, Hinds, J, Garcia Quintanilla, L, Smith, C, Campos, J, Brill, A, Pike, J, Khan, A, Poulter, N, Kavanagh, D, Watson, S, Watson, CN, Clifford, H, Huissoon, A, Pollitt, A, Eble, JA, Pratt, D, Watson, S & Hughes, C 2021, 'Low-dose Btk inhibitors selectively block platelet activation by CLEC-2', Haematologica, vol. 106, no. 1, pp. 208-219. https://doi.org/10.3324/haematol.2019.218545
The UK GAPP Study Group, Stapley, R, Poulter, N, Khan, A, Smith, C, Bignell, P, Fratter, C, Lester, W, Lowe, G & Morgan, N 2021, 'Rare missense variants in Tropomyosin-4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects and excessive bleeding', Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15584
Slater, A, Di, Y, Clark, J, Jooss, N, Martin, E, Alenazy, F, Thomas, MR, Ariëns, RAS, Herr, AB, Poulter, N, Emsley, J & Watson, S 2021, 'Structural characterisation of a novel GPVI nanobody-complex reveals a biologically active domain-swapped GPVI dimer', Blood, vol. 2021, no. 00, pp. 1-20. https://doi.org/10.1182/blood.2020009440
Yule, J, Morgan, N & Poulter, N 2020, 'New insights into Glycoprotein Ibα desialylation-mediated platelet clearance', Platelets, vol. 31, no. 5, pp. 621-623. https://doi.org/10.1080/09537104.2020.1764922
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