Dr Mohammed Hadis BSc (Hons), PhD

Dr Mohammed Hadis

School of Dentistry
Research Fellow

Contact details

Mohammed Hadis is a Research Fellow in Biomaterials at the School of Dentistry in the Institute of Clinical Sciences. His areas of research include the interaction of light with materials as well at the biological interface. As such his research areas cover photochemistry, photobiology and photophysics.

Qualifications

  • PhD Biomaterials 2011: “Polymerisation kinetics and optical phenomena of photoactive dental resins”.
  • BSc (Hons) (Chemistry and Pharmacology) 2007.

Biography

Mohammed Hadis graduated with a BSc (hons) in Chemistry and Pharmacology from the University of Birmingham in 2004 and went onto study a PhD in Biomaterials at the School of Dentistry. Following his graduation in 2011, he was appointed as a Research Fellow to continue his research in the development of novel biomaterials and technologies for biomedical applications. His research interests and expertise relates to biomedical applications of lights from photo-curing of composite materials to interaction of light with cells, tissue, molecules and micro-organisms. He provides key skills in the field of photonics for the development of novel technologies and currently working on projects funded by the National Institute of Health Research and The Ministry of Defence as well as other private investors. His research has been awarded several prestigious awards including the Paffenbarger Award for outstanding research and the Heraeus Kulzer Award for innovative testing design.

Teaching

Teaching, assessment, supervision and lab training:

  • BMedSc
  • MSc (GDP)

Research

After completing his PhD in 2011 he was appointed as a Research Fellow and has worked alongside a multidisciplinary team developing advanced polymer biomaterials for dental applications and novel therapeutic medical technologies. He has worked on several research projects including those funded by The National Institute of Health Research (NHIR), The Ministry of Defence (MoD), Engineering and Physical Sciences Research Council (ESPRC) and other projects funded by private investors. Many of those projects have forged important collaborations internally, nationally and internationally to provide unique interdisciplinary research groups in related fields that will underpin current and future biomaterial technology development. His research areas include:

  • Photochemistry

 Understanding the complex mechanism of using light energy for spatial and temporal control of polymerisation reaction. This area of research relates specifically to his PhD which was an ESPRC funded collaborative National Physical Laboratory (NPL) project (EP/EO26257/1) in which a bespoke interferometer was developed (DynacureTM) for measurement of optical and physical properties of light curable dental materials. The equipment has been used to explore fundamental aspects photoinitiator and  materials chemistry in order to further understand and improve polymerisation efficiency. The work has led to productive collaborations both nationally and internationally.

  • Applied Biomaterials

 As part of the internationally recognised Biomaterials Unit that has a strong materials science-biological interface, we are routinely involved in mechanical and physical characterisation of materials using a range of  physical, optical and analytical techniques. The Biomaterials Unit has attracted funding through a range of funding streams including ESPRC, NIHR, BBSRC and private investors. The funding has led to greater understanding of material behaviour has enabled the realisation of better chemistries for potentially more effective and reliable biomedical applications. We are also currently developing novel biomaterials and smart biomaterials for biomedical applications.

  • Applied Biophotonics

Our expertise in photophysics and photochemistry has allowed for a transition into an exciting new area of research which involves photobiology (photobiomodulation) and has led to the establishment of the Biophotonics Group. Photobiomodulation is the use of light energy to obtain therapeutic effects clinically which include accelerating tissue healing, reducing inflammation and inducing analgesia. This area of research has attracted both internal and external collaborations and has led to several successful funding bids including those from the NIHR and MoD. We are currently developing a range of novel therapeutic biomedical technologies.

Other activities

  • Member of the International Association of Dental Research (IADR)
  • Member of the Academy of Dental Materials (ADM) 
  • Postdoctoral/ Early Researcher Career Development and Training (PERCAT) representative:
  • Editorial Board Member for European Journal of Prosthodontics and Restorative Dentistry

 Awards

  • Paffenbarger Award, Academy of Dental Materials, 2009. “Photoinitiator type and applicability of exposure reciprocity law in filled and unfilled photoactive resins”. J Leprince, M Hadis, AC Shortall, JL Ferracane, J Devaux, G Leloup, WM Palin
  • Heraeus Kulzer Award for innovation in materials testing, International Association for Dental Research, Barcelona, 2010. “Competitive light absorbers in curing photoactive resins”. M Hadis, AC Shortall, WM Palin

Publications

  • Shaw K, Martins R, Hadis MA, Burke T and Palin W (2016). ‘Own-Label’ Versus Branded Commercial Dental Resin Composite Materials: Mechanical and Physical Property Comparison. EJPRD, doi: 10.1922/EJPRD_01559Shaw08
  • Hadis MA, Zainal SA, Holder MJ, Carroll JD, Cooper PR, Milward MR and Palin WM (2016). The dark art of light measurement: accurate radiometry for low-level light therapy. Lasers Med Sci, 31: 789-809
  • Milward MR, Hadis MA, Cooper PR, Gorecki P and Palin WM (2015). Biomodulatory effects of laser irradiation on dental pulp cells in vitro. SPIE Proc. SPIE 9309, Mechanisms of low-light therapy X, 930906, doi: 10.1117/12.2077717
  • Hadis MA, Cooper PR, Milward MR, Gorecki P, Tarte E, Churm J and Palin WM (2015). The effect of UV-Vis to near-infrared light on the biological response of human dental pulp cells. Proc. SPIE 9309, Mechanisms for low-light therapy X, 930906, doi: 10.1117/12.2077645
  • Palin WM, Hadis MA, Milward MR, Cooper PR (2015). Beam profile measurements for dental phototherapy: the effect of distance, wavelength and tissue thickness. Proc. SPIE 9309, Mechanisms for low-light therapy X, 930906, doi: 10.1117/12.2077628
  • Milward MR., Holder MJ, Palin WM, Hadis MA, Carroll JD and Cooper PR (2014). Low level light therapy (LLLT) for the treatment and management of dental and oral diseases. Dental Update: 763-772
  • Carroll JD, Milward MR, Cooper PR., Hadis M and Palin WM (2014). Developments in low level light therapy (LLLT) for dentistry. Dental Materials, 30: 465-475
  • Palin WM, Hadis MA, Leprince JG, Leloup G, Boland L, Fleming GJP, Krastl G and Watts DC (2014). Reduced polymerization stress of MAPO-containing resin composites with increased curing speed, degree of conversion and mechanical properties. Dental Materials, 30: 507-516
  • Leprince J, Palin WM,  Hadis M, Devaux J, Leloup G (2013). Progress in Dimethacrylate-based dental composite technology and curing efficiency. Dental Materials,  29: 139-156
  • Leprince J, Hadis M, Devaux J, Leloup G and Palin W (2012). Phoshine oxide-based adhesives: Reduced curing time and increased polymer conversion. Dental Materials 28, e10
  • Hadis M, Shortall AC, Palin WM (2012). Specimen aspect ratio and light transmission in photoactive dental resins. Dental Materials, 28: 1154-1161
  • Holder MJ, Milward MR, Palin WM, Hadis MA, Cooper PR (2012). Red light emitting diode effects on dental pulp cells. Journal of Dental Research, 91: 961-966
  • Hadis M, Shortall AC, Palin WM (2012) . Competitive light absorbers in photo-active dental resin based materials. Dental Materials,  28: 831-841
  • Hadis M, Leprince J, Shortall AC, Devaux J, Leloup G, Palin WM (2011). High irradiance curing and anomalies of exposure reciprocity law in resin based materials. Journal of Dentistry, 39: 549-557
  • Leprince J, Hadis M, Shortall AC, Ferracane JL, Devaux J, Leloup G, Palin WM (2011). Photoinitiator type and applicability of exposure reciprocity in filled and unfilled photoactive resins. Dental Materials, 27: 157:164
  • Leprince J, Hadis M, Ferracane JL, Shortall AC, Leloup G and Palin WM. Lucirin-TPO: Photoinitiator reactivity and curing time reduction (2010). Dental Materials, 26: e127-e128
  • Hadis M, Tomlins P, Shortall AC, Palin WM (2010). Dynamic monitoring of refractive index change through photoactive resins. Dental Materials, 26: 1106-111